SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ci2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_A_115A2_2
(HMG-COA REDUCTASE)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 8 GLU B 107
LEU B 100
ALA B 160
LEU B  98
 None
 0.87A 1hwiB-4ci2B:
undetectable		 1hwiB-4ci2B:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_C_115C4_2
(HMG-COA REDUCTASE)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 8 GLU B 107
LEU B 100
ALA B 160
LEU B  98
 None
 0.89A 1hwiD-4ci2B:
undetectable		 1hwiD-4ci2B:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_D_115D3_1
(HMG-COA REDUCTASE)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 8 GLU B 107
LEU B 100
ALA B 160
LEU B  98
 None
 0.89A 1hwiC-4ci2B:
undetectable		 1hwiC-4ci2B:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 6 GLY B 162
ILE B  93
GLN B  96
VAL B 123
 None
 1.06A 1rs7B-4ci2B:
undetectable		 1rs7B-4ci2B:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_T_NCTT1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 8 LEU B 342
TYR B  60
THR B  56
TYR B 351
 None
 1.42A 1uw6P-4ci2B:
undetectable
1uw6T-4ci2B:
undetectable		 1uw6P-4ci2B:
18.94
1uw6T-4ci2B:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA6_B_STRB402_1
(MINERALOCORTICOID
RECEPTOR)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		5 / 12 LEU B  98
ALA B 160
LEU B  85
LEU B 114
THR B  72
 None
 1.46A 2aa6B-4ci2B:
undetectable		 2aa6B-4ci2B:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		5 / 12 CYH B 328
LEU B 424
LEU B 419
CYH B 396
LEU B 370
 ZN  B1428 (-2.2A)
None
None
ZN  B1428 (-2.2A)
None
 1.24A 2bxfA-4ci2B:
2.1		 2bxfA-4ci2B:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FW3_B_ETSB303_1
(CARBONIC ANHYDRASE 4)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		5 / 12 HIS B  58
VAL B 352
ILE B 358
LEU B  98
THR B  97
 None
 0.86A 3fw3B-4ci2B:
undetectable		 3fw3B-4ci2B:
20.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CI1_B_EF2B1429_1
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		10 / 10 ASN B 353
PRO B 354
HIS B 355
HIS B 359
HIS B 380
SER B 381
TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-4.1A)
LVY  B1429 (-4.7A)
LVY  B1429 (-4.5A)
LVY  B1429 ( 4.8A)
LVY  B1429 (-4.0A)
LVY  B1429 (-3.8A)
LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.08A 4ci1B-4ci2B:
58.1		 4ci1B-4ci2B:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CI1_B_EF2B1429_1
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		6 / 10 ASN B 353
PRO B 354
HIS B 359
HIS B 380
SER B 381
PHE B 383
 LVY  B1429 (-4.1A)
LVY  B1429 (-4.7A)
LVY  B1429 ( 4.8A)
LVY  B1429 (-4.0A)
LVY  B1429 (-3.8A)
None
 1.36A 4ci1B-4ci2B:
58.1		 4ci1B-4ci2B:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CI3_B_Y70B1429_1
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		10 / 10 ASN B 353
PRO B 354
HIS B 355
HIS B 359
HIS B 380
SER B 381
TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-4.1A)
LVY  B1429 (-4.7A)
LVY  B1429 (-4.5A)
LVY  B1429 ( 4.8A)
LVY  B1429 (-4.0A)
LVY  B1429 (-3.8A)
LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.12A 4ci3B-4ci2B:
58.3		 4ci3B-4ci2B:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 6 GLY B 162
ILE B  93
GLN B  96
VAL B 123
 None
 1.07A 4d39B-4ci2B:
undetectable		 4d39B-4ci2B:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVC_B_HFGB1602_0
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		5 / 12 LEU B  98
VAL B  90
GLU B 107
THR B 173
GLY B 177
 None
 1.26A 4hvcB-4ci2B:
undetectable		 4hvcB-4ci2B:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA505_0
(RNA POLYMERASE
3D-POL)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		3 / 3 CYH B 320
ASN B 318
LYS B 336
 None
 1.42A 4k50A-4ci2B:
undetectable		 4k50A-4ci2B:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_ACTA803_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 6 GLY B 162
ILE B  93
GLN B  96
VAL B 123
 None
 1.07A 4kcnA-4ci2B:
undetectable		 4kcnA-4ci2B:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L78_A_ACTA1327_0
(PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 4 VAL B 108
THR B 155
GLU B 147
GLU B 148
 None
 1.35A 4l78A-4ci2B:
undetectable		 4l78A-4ci2B:
15.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TZ4_C_LVYC502_1
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		9 / 9 ASN B 353
PRO B 354
HIS B 355
HIS B 380
SER B 381
TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-4.1A)
LVY  B1429 (-4.7A)
LVY  B1429 (-4.5A)
LVY  B1429 (-4.0A)
LVY  B1429 (-3.8A)
LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.26A 4tz4C-4ci2B:
18.0		 4tz4C-4ci2B:
87.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TZC_A_EF2A504_1
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 5 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.29A 4tzcA-4ci2B:
17.6		 4tzcA-4ci2B:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TZC_C_EF2C502_1
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 5 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.24A 4tzcC-4ci2B:
17.4		 4tzcC-4ci2B:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TZC_D_EF2D505_1
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 8 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.21A 4tzcB-4ci2B:
16.9
4tzcD-4ci2B:
16.9		 4tzcB-4ci2B:
21.88
4tzcD-4ci2B:
21.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TZU_A_Y70A504_1
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 5 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.25A 4tzuA-4ci2B:
17.4		 4tzuA-4ci2B:
90.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TZU_B_Y70B505_1
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 7 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.23A 4tzuB-4ci2B:
17.7
4tzuC-4ci2B:
17.5		 4tzuB-4ci2B:
90.74
4tzuC-4ci2B:
90.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TZU_C_Y70C504_1
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 7 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.27A 4tzuB-4ci2B:
17.7
4tzuC-4ci2B:
17.5		 4tzuB-4ci2B:
90.74
4tzuC-4ci2B:
90.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TZU_D_Y70D503_1
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 5 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.34A 4tzuD-4ci2B:
17.8		 4tzuD-4ci2B:
90.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Y_A_EF2A151_1
(CEREBLON ISOFORM 4)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		5 / 7 ASN B 353
PRO B 354
TRP B 382
TRP B 388
TRP B 402
 LVY  B1429 (-4.1A)
LVY  B1429 (-4.7A)
LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
 0.42A 4v2yA-4ci2B:
15.9		 4v2yA-4ci2B:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Y_B_EF2B151_1
(CEREBLON ISOFORM 4)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		5 / 7 ASN B 353
PRO B 354
TRP B 382
TRP B 388
TRP B 402
 LVY  B1429 (-4.1A)
LVY  B1429 (-4.7A)
LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
 0.42A 4v2yB-4ci2B:
16.3		 4v2yB-4ci2B:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Y_C_EF2C151_1
(CEREBLON ISOFORM 4)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		5 / 7 ASN B 353
PRO B 354
TRP B 382
TRP B 388
TRP B 402
 LVY  B1429 (-4.1A)
LVY  B1429 (-4.7A)
LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
 0.66A 4v2yC-4ci2B:
14.9		 4v2yC-4ci2B:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_A_Y70A151_1
(CEREBLON ISOFORM 4)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		5 / 7 ASN B 353
PRO B 354
TRP B 382
TRP B 388
TRP B 402
 LVY  B1429 (-4.1A)
LVY  B1429 (-4.7A)
LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
 0.41A 4v2zA-4ci2B:
15.9		 4v2zA-4ci2B:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_B_Y70B151_1
(CEREBLON ISOFORM 4)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		5 / 8 ASN B 353
PRO B 354
TRP B 382
TRP B 388
TRP B 402
 LVY  B1429 (-4.1A)
LVY  B1429 (-4.7A)
LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
 0.42A 4v2zB-4ci2B:
16.2		 4v2zB-4ci2B:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_C_Y70C151_1
(CEREBLON ISOFORM 4)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		5 / 8 ASN B 353
PRO B 354
TRP B 382
TRP B 388
TRP B 402
 LVY  B1429 (-4.1A)
LVY  B1429 (-4.7A)
LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
 0.62A 4v2zC-4ci2B:
14.7		 4v2zC-4ci2B:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V30_A_LVYA151_1
(CEREBLON ISOFORM 4)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		5 / 7 ASN B 353
PRO B 354
TRP B 382
TRP B 388
TRP B 402
 LVY  B1429 (-4.1A)
LVY  B1429 (-4.7A)
LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
 0.45A 4v30A-4ci2B:
16.0		 4v30A-4ci2B:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V30_B_LVYB151_1
(CEREBLON ISOFORM 4)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		5 / 8 ASN B 353
PRO B 354
TRP B 382
TRP B 388
TRP B 402
 LVY  B1429 (-4.1A)
LVY  B1429 (-4.7A)
LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
 0.42A 4v30B-4ci2B:
16.3		 4v30B-4ci2B:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V30_C_LVYC151_1
(CEREBLON ISOFORM 4)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		5 / 7 ASN B 353
PRO B 354
TRP B 382
TRP B 388
TRP B 402
 LVY  B1429 (-4.1A)
LVY  B1429 (-4.7A)
LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
 0.58A 4v30C-4ci2B:
14.5		 4v30C-4ci2B:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V32_A_EF2A151_1
(CEREBLON ISOFORM 4)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		6 / 7 ASN B 353
PRO B 354
TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-4.1A)
LVY  B1429 (-4.7A)
LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.41A 4v32A-4ci2B:
15.9		 4v32A-4ci2B:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V32_B_EF2B151_1
(CEREBLON ISOFORM 4)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		6 / 7 ASN B 353
PRO B 354
TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-4.1A)
LVY  B1429 (-4.7A)
LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.46A 4v32B-4ci2B:
16.4		 4v32B-4ci2B:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V32_C_EF2C151_1
(CEREBLON ISOFORM 4)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		6 / 7 ASN B 353
PRO B 354
TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-4.1A)
LVY  B1429 (-4.7A)
LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.60A 4v32C-4ci2B:
14.5		 4v32C-4ci2B:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_B_RTZB602_2
(CYTOCHROME P450 2D6)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		3 / 3 GLU B 360
ILE B 298
ALA B 287
 None
 0.51A 4wnwB-4ci2B:
undetectable		 4wnwB-4ci2B:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_A_AZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		5 / 11 HIS B  58
VAL B 352
LEU B  98
THR B  97
ALA B 160
 None
 1.03A 4ygfA-4ci2B:
undetectable		 4ygfA-4ci2B:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_C_AZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		5 / 11 HIS B  58
VAL B 352
LEU B  98
THR B  97
ALA B 160
 None
 1.04A 4ygfC-4ci2B:
undetectable		 4ygfC-4ci2B:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_D_AZMD303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		5 / 11 HIS B  58
VAL B 352
LEU B  98
THR B  97
ALA B 160
 None
 1.09A 4ygfD-4ci2B:
undetectable		 4ygfD-4ci2B:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_G_AZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		5 / 12 HIS B  58
VAL B 352
LEU B  98
THR B  97
ALA B 160
 None
 1.03A 4ygfG-4ci2B:
undetectable		 4ygfG-4ci2B:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_A_MZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		5 / 12 HIS B  58
VAL B 352
LEU B  98
THR B  97
ALA B 160
 None
 1.11A 4yhaA-4ci2B:
undetectable		 4yhaA-4ci2B:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_B_MZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		5 / 10 HIS B  58
VAL B 352
LEU B  98
THR B  97
ALA B 160
 None
 1.06A 4yhaB-4ci2B:
undetectable		 4yhaB-4ci2B:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_D_MZMD302_1
(ALPHA-CARBONIC
ANHYDRASE)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		5 / 11 HIS B  58
VAL B 352
LEU B  98
THR B  97
ALA B 160
 None
 1.05A 4yhaD-4ci2B:
undetectable		 4yhaD-4ci2B:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_E_MZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		5 / 12 HIS B  58
VAL B 352
LEU B  98
THR B  97
ALA B 160
 None
 1.09A 4yhaE-4ci2B:
undetectable		 4yhaE-4ci2B:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_F_MZMF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		5 / 10 HIS B  58
VAL B 352
LEU B  98
THR B  97
ALA B 160
 None
 1.25A 4yhaF-4ci2B:
undetectable		 4yhaF-4ci2B:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_G_MZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		5 / 12 HIS B  58
VAL B 352
LEU B  98
THR B  97
ALA B 160
 None
 1.07A 4yhaG-4ci2B:
undetectable		 4yhaG-4ci2B:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_H_MZMH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		5 / 10 HIS B  58
VAL B 352
LEU B  98
THR B  97
ALA B 160
 None
 1.07A 4yhaH-4ci2B:
undetectable		 4yhaH-4ci2B:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMH_A_EF2A151_1
(CEREBLON ISOFORM 4)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		5 / 7 ASN B 353
PRO B 354
TRP B 382
TRP B 388
TRP B 402
 LVY  B1429 (-4.1A)
LVY  B1429 (-4.7A)
LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
 0.49A 5amhA-4ci2B:
16.2		 5amhA-4ci2B:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_A_EF2A151_1
(CEREBLON ISOFORM 4)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		5 / 7 ASN B 353
PRO B 354
TRP B 382
TRP B 388
TRP B 402
 LVY  B1429 (-4.1A)
LVY  B1429 (-4.7A)
LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
 0.43A 5amiA-4ci2B:
16.2		 5amiA-4ci2B:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_B_EF2B151_1
(CEREBLON ISOFORM 4)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		6 / 8 ASN B 353
PRO B 354
SER B 381
TRP B 382
TRP B 388
TRP B 402
 LVY  B1429 (-4.1A)
LVY  B1429 (-4.7A)
LVY  B1429 (-3.8A)
LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
 0.39A 5amiB-4ci2B:
16.4		 5amiB-4ci2B:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMJ_A_EF2A151_1
(CEREBLON ISOFORM 4)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		5 / 7 ASN B 353
PRO B 354
TRP B 382
TRP B 388
TRP B 402
 LVY  B1429 (-4.1A)
LVY  B1429 (-4.7A)
LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
 0.37A 5amjA-4ci2B:
16.0		 5amjA-4ci2B:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMJ_B_EF2B151_1
(CEREBLON ISOFORM 4)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		5 / 7 ASN B 353
PRO B 354
TRP B 382
TRP B 388
TRP B 402
 LVY  B1429 (-4.1A)
LVY  B1429 (-4.7A)
LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
 0.39A 5amjB-4ci2B:
16.3		 5amjB-4ci2B:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMK_A_EF2A151_1
(CEREBLON ISOFORM 4)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		5 / 8 ASN B 353
PRO B 354
TRP B 382
TRP B 388
TRP B 402
 LVY  B1429 (-4.1A)
LVY  B1429 (-4.7A)
LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
 0.46A 5amkA-4ci2B:
16.2		 5amkA-4ci2B:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMK_B_EF2B151_1
(CEREBLON ISOFORM 4)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		5 / 7 ASN B 353
PRO B 354
TRP B 382
TRP B 388
TRP B 402
 LVY  B1429 (-4.1A)
LVY  B1429 (-4.7A)
LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
 0.46A 5amkB-4ci2B:
16.3		 5amkB-4ci2B:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB5_A_010A609_0
(HNL ISOENZYME 5)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		5 / 11 ALA B 160
ALA B 140
VAL B 123
LEU B 102
VAL B  88
 None
 1.06A 5eb5A-4ci2B:
undetectable		 5eb5A-4ci2B:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB5_B_010B607_0
(HNL ISOENZYME 5)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		5 / 10 ALA B 160
ALA B 140
VAL B 123
LEU B 102
VAL B  88
 None
 1.13A 5eb5B-4ci2B:
undetectable		 5eb5B-4ci2B:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECO_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 6 THR B 120
ALA B 140
THR B 139
VAL B 123
 None
 0.98A 5ecoA-4ci2B:
undetectable		 5ecoA-4ci2B:
21.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FQD_B_LVYB1438_1
(PROTEIN CEREBLON
CASEIN KINASE I
ISOFORM ALPHA)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		8 / 11 ASN B 353
PRO B 354
HIS B 355
HIS B 380
TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-4.1A)
LVY  B1429 (-4.7A)
LVY  B1429 (-4.5A)
LVY  B1429 (-4.0A)
LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.36A 5fqdB-4ci2B:
53.5
5fqdC-4ci2B:
0.0		 5fqdB-4ci2B:
79.32
5fqdC-4ci2B:
21.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FQD_B_LVYB1438_1
(PROTEIN CEREBLON
CASEIN KINASE I
ISOFORM ALPHA)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		6 / 11 GLU B 379
HIS B 380
TRP B 382
TRP B 388
TRP B 402
PHE B 404
 None
LVY  B1429 (-4.0A)
LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.87A 5fqdB-4ci2B:
53.5
5fqdC-4ci2B:
0.0		 5fqdB-4ci2B:
79.32
5fqdC-4ci2B:
21.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FQD_E_LVYE1438_1
(PROTEIN CEREBLON
CASEIN KINASE I
ISOFORM ALPHA)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		9 / 12 ASN B 353
PRO B 354
HIS B 355
HIS B 380
SER B 381
TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-4.1A)
LVY  B1429 (-4.7A)
LVY  B1429 (-4.5A)
LVY  B1429 (-4.0A)
LVY  B1429 (-3.8A)
LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.34A 5fqdE-4ci2B:
51.1
5fqdF-4ci2B:
0.0		 5fqdE-4ci2B:
79.32
5fqdF-4ci2B:
21.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FQD_E_LVYE1438_1
(PROTEIN CEREBLON
CASEIN KINASE I
ISOFORM ALPHA)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		7 / 12 GLU B 379
HIS B 380
SER B 381
TRP B 382
TRP B 388
TRP B 402
PHE B 404
 None
LVY  B1429 (-4.0A)
LVY  B1429 (-3.8A)
LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.83A 5fqdE-4ci2B:
51.1
5fqdF-4ci2B:
0.0		 5fqdE-4ci2B:
79.32
5fqdF-4ci2B:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GTR_A_ESTA601_2
(ESTROGEN RECEPTOR)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 5 LEU B 310
LEU B 290
PHE B 282
LEU B 263
 None
 1.03A 5gtrA-4ci2B:
undetectable		 5gtrA-4ci2B:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_A_EF2A202_0
(CEREBLON ISOFORM 4)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		5 / 7 ASN B 353
PRO B 354
TRP B 382
TRP B 388
TRP B 402
 LVY  B1429 (-4.1A)
LVY  B1429 (-4.7A)
LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
 0.46A 5oh1A-4ci2B:
16.0		 5oh1A-4ci2B:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_B_EF2B202_0
(CEREBLON ISOFORM 4)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		5 / 7 ASN B 353
PRO B 354
TRP B 382
TRP B 388
TRP B 402
 LVY  B1429 (-4.1A)
LVY  B1429 (-4.7A)
LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
 0.52A 5oh1B-4ci2B:
16.3		 5oh1B-4ci2B:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_C_9UQC202_0
(CEREBLON ISOFORM 4)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		5 / 8 ASN B 353
PRO B 354
TRP B 382
TRP B 388
TRP B 402
 LVY  B1429 (-4.1A)
LVY  B1429 (-4.7A)
LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
 0.69A 5oh1C-4ci2B:
14.7		 5oh1C-4ci2B:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH3_A_9V2A202_0
(CEREBLON ISOFORM 4)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		5 / 7 ASN B 353
PRO B 354
TRP B 382
TRP B 388
TRP B 402
 LVY  B1429 (-4.1A)
LVY  B1429 (-4.7A)
LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
 0.38A 5oh3A-4ci2B:
16.1		 5oh3A-4ci2B:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH3_B_9V2B202_0
(CEREBLON ISOFORM 4)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		5 / 7 ASN B 353
PRO B 354
TRP B 382
TRP B 388
TRP B 402
 LVY  B1429 (-4.1A)
LVY  B1429 (-4.7A)
LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
 0.46A 5oh3B-4ci2B:
16.4		 5oh3B-4ci2B:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		5 / 10 HIS B  58
VAL B 352
LEU B  98
THR B  97
ALA B 160
 None
 1.06A 5tt3A-4ci2B:
undetectable		 5tt3A-4ci2B:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_B_EZLB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		5 / 9 HIS B  58
VAL B 352
LEU B  98
THR B  97
ALA B 160
 None
 1.03A 5tt3B-4ci2B:
undetectable		 5tt3B-4ci2B:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_C_EZLC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		5 / 10 HIS B  58
VAL B 352
LEU B  98
THR B  97
ALA B 160
 None
 1.06A 5tt3C-4ci2B:
undetectable		 5tt3C-4ci2B:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_E_EZLE303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		5 / 9 HIS B  58
VAL B 352
LEU B  98
THR B  97
ALA B 160
 None
 1.05A 5tt3E-4ci2B:
undetectable		 5tt3E-4ci2B:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_G_EZLG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		5 / 9 HIS B  58
VAL B 352
LEU B  98
THR B  97
ALA B 160
 None
 1.10A 5tt3G-4ci2B:
undetectable		 5tt3G-4ci2B:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		5 / 8 HIS B  58
VAL B 352
LEU B  98
THR B  97
ALA B 160
 None
 1.08A 5tt3H-4ci2B:
undetectable		 5tt3H-4ci2B:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_C_HFGC1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		5 / 12 LEU B  98
VAL B  90
GLU B 107
THR B 173
GLY B 177
 None
 1.24A 5xipC-4ci2B:
undetectable		 5xipC-4ci2B:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YIZ_A_EF2A501_1
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 5 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.27A 5yizA-4ci2B:
17.2		 5yizA-4ci2B:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YIZ_B_EF2B501_1
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 5 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.20A 5yizb-4ci2B:
17.4		 5yizb-4ci2B:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YIZ_D_EF2D501_1
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 5 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.27A 5yizD-4ci2B:
17.2		 5yizD-4ci2B:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YIZ_E_EF2E501_1
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 5 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.20A 5yize-4ci2B:
17.7		 5yize-4ci2B:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YIZ_G_EF2G501_1
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 7 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.28A 5yizG-4ci2B:
17.2
5yizY-4ci2B:
17.7		 5yizG-4ci2B:
17.79
5yizY-4ci2B:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YIZ_H_EF2H501_1
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 5 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.23A 5yizh-4ci2B:
17.3		 5yizh-4ci2B:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YIZ_J_EF2J501_1
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 5 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.25A 5yizJ-4ci2B:
17.5		 5yizJ-4ci2B:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YIZ_K_EF2K501_1
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 7 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.23A 5yizk-4ci2B:
17.7
5yizt-4ci2B:
17.1		 5yizk-4ci2B:
17.79
5yizt-4ci2B:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YIZ_M_EF2M501_1
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 5 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.22A 5yizM-4ci2B:
17.7		 5yizM-4ci2B:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YIZ_N_EF2N501_1
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 5 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.24A 5yizn-4ci2B:
17.5		 5yizn-4ci2B:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YIZ_P_EF2P501_1
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 5 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.19A 5yizP-4ci2B:
17.4		 5yizP-4ci2B:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YIZ_Q_EF2Q501_1
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 5 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.19A 5yizq-4ci2B:
17.5		 5yizq-4ci2B:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YIZ_S_EF2S501_1
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 5 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.22A 5yizS-4ci2B:
17.5		 5yizS-4ci2B:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YIZ_T_EF2T501_1
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 7 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.26A 5yizk-4ci2B:
17.7
5yizt-4ci2B:
17.1		 5yizk-4ci2B:
17.79
5yizt-4ci2B:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YIZ_V_EF2V501_1
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 5 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.23A 5yizV-4ci2B:
17.3		 5yizV-4ci2B:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YIZ_Y_EF2Y501_1
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 7 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.21A 5yizG-4ci2B:
17.2
5yizY-4ci2B:
17.7		 5yizG-4ci2B:
17.79
5yizY-4ci2B:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ0_A_EF2A501_1
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 5 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.26A 5yj0A-4ci2B:
17.2		 5yj0A-4ci2B:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ0_B_EF2B501_1
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 5 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.20A 5yj0b-4ci2B:
17.4		 5yj0b-4ci2B:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ0_D_EF2D501_1
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 5 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.28A 5yj0D-4ci2B:
17.1		 5yj0D-4ci2B:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ0_E_EF2E501_1
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 5 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.19A 5yj0e-4ci2B:
17.7		 5yj0e-4ci2B:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ0_G_EF2G501_1
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 7 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.27A 5yj0G-4ci2B:
17.2
5yj0Y-4ci2B:
17.7		 5yj0G-4ci2B:
17.79
5yj0Y-4ci2B:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ0_H_EF2H501_1
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 5 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.24A 5yj0h-4ci2B:
17.3		 5yj0h-4ci2B:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ0_J_EF2J501_1
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 5 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.27A 5yj0J-4ci2B:
17.5		 5yj0J-4ci2B:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ0_K_EF2K501_1
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 7 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.19A 5yj0k-4ci2B:
17.8
5yj0t-4ci2B:
17.0		 5yj0k-4ci2B:
17.79
5yj0t-4ci2B:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ0_M_EF2M501_1
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 5 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.20A 5yj0M-4ci2B:
17.7		 5yj0M-4ci2B:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ0_N_EF2N501_1
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 5 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.26A 5yj0n-4ci2B:
17.5		 5yj0n-4ci2B:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ0_P_EF2P501_1
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 5 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.20A 5yj0P-4ci2B:
17.5		 5yj0P-4ci2B:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ0_Q_EF2Q501_1
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 5 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.21A 5yj0q-4ci2B:
17.5		 5yj0q-4ci2B:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ0_S_EF2S501_1
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 5 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.21A 5yj0S-4ci2B:
17.5		 5yj0S-4ci2B:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ0_T_EF2T501_1
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 7 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.27A 5yj0k-4ci2B:
17.8
5yj0t-4ci2B:
17.0		 5yj0k-4ci2B:
17.79
5yj0t-4ci2B:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ0_V_EF2V501_1
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 5 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.25A 5yj0V-4ci2B:
17.3		 5yj0V-4ci2B:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ0_Y_EF2Y501_1
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 7 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.20A 5yj0G-4ci2B:
17.2
5yj0Y-4ci2B:
17.7		 5yj0G-4ci2B:
17.79
5yj0Y-4ci2B:
17.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YJ1_A_6ELA501_0
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 5 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.30A 5yj1A-4ci2B:
17.2		 5yj1A-4ci2B:
34.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YJ1_B_6ELB501_0
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 5 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.25A 5yj1b-4ci2B:
17.3		 5yj1b-4ci2B:
34.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YJ1_D_6ELD501_0
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 5 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.28A 5yj1D-4ci2B:
17.2		 5yj1D-4ci2B:
34.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YJ1_E_6ELE501_0
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 5 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.20A 5yj1e-4ci2B:
17.4		 5yj1e-4ci2B:
34.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YJ1_G_6ELG501_0
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 8 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.28A 5yj1G-4ci2B:
17.0
5yj1Y-4ci2B:
17.4		 5yj1G-4ci2B:
34.47
5yj1Y-4ci2B:
34.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YJ1_G_6ELG501_0
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 8 TRP B 388
TRP B 402
PHE B 404
HIS B 355
 LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
LVY  B1429 (-4.5A)
 1.21A 5yj1G-4ci2B:
17.0
5yj1Y-4ci2B:
17.4		 5yj1G-4ci2B:
34.47
5yj1Y-4ci2B:
34.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YJ1_H_6ELH501_0
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 5 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.24A 5yj1h-4ci2B:
17.2		 5yj1h-4ci2B:
34.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YJ1_J_6ELJ501_0
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 5 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.25A 5yj1J-4ci2B:
17.4		 5yj1J-4ci2B:
34.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YJ1_K_6ELK501_0
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 7 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.25A 5yj1k-4ci2B:
17.6
5yj1t-4ci2B:
17.1		 5yj1k-4ci2B:
34.47
5yj1t-4ci2B:
34.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YJ1_M_6ELM501_0
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 5 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.22A 5yj1M-4ci2B:
17.4		 5yj1M-4ci2B:
34.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YJ1_N_6ELN501_0
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 5 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.24A 5yj1n-4ci2B:
17.4		 5yj1n-4ci2B:
34.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YJ1_P_6ELP501_0
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 5 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.21A 5yj1P-4ci2B:
17.3		 5yj1P-4ci2B:
34.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YJ1_Q_6ELQ501_0
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 5 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.24A 5yj1q-4ci2B:
17.4		 5yj1q-4ci2B:
34.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YJ1_S_6ELS501_0
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 5 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.22A 5yj1S-4ci2B:
17.4		 5yj1S-4ci2B:
34.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YJ1_T_6ELT501_0
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 8 HIS B 355
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-4.5A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 1.19A 5yj1k-4ci2B:
17.6
5yj1t-4ci2B:
17.1		 5yj1k-4ci2B:
34.47
5yj1t-4ci2B:
34.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YJ1_T_6ELT501_0
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 8 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.30A 5yj1k-4ci2B:
17.6
5yj1t-4ci2B:
17.1		 5yj1k-4ci2B:
34.47
5yj1t-4ci2B:
34.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YJ1_V_6ELV501_0
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 5 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.22A 5yj1V-4ci2B:
17.2		 5yj1V-4ci2B:
34.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YJ1_Y_6ELY501_0
(PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		4 / 7 TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.21A 5yj1G-4ci2B:
17.0
5yj1Y-4ci2B:
17.4		 5yj1G-4ci2B:
34.47
5yj1Y-4ci2B:
34.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_D_GLYD713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		3 / 3 ARG B  71
HIS B  69
ARG B 119
 None
 1.10A 6dwdD-4ci2B:
undetectable		 6dwdD-4ci2B:
22.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H0F_B_Y70B502_0
(IKAROS (IKZF1)
PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		8 / 12 ASN B 353
PRO B 354
HIS B 355
HIS B 380
TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-4.1A)
LVY  B1429 (-4.7A)
LVY  B1429 (-4.5A)
LVY  B1429 (-4.0A)
LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.43A 6h0fB-4ci2B:
29.9
6h0fC-4ci2B:
undetectable		 6h0fB-4ci2B:
46.28
6h0fC-4ci2B:
4.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H0F_B_Y70B502_0
(IKAROS (IKZF1)
PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		6 / 12 GLU B 379
HIS B 380
TRP B 382
TRP B 388
TRP B 402
PHE B 404
 None
LVY  B1429 (-4.0A)
LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.96A 6h0fB-4ci2B:
29.9
6h0fC-4ci2B:
undetectable		 6h0fB-4ci2B:
46.28
6h0fC-4ci2B:
4.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H0F_E_Y70E502_0
(IKAROS (IKZF1)
PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		8 / 12 ASN B 353
PRO B 354
HIS B 355
HIS B 380
TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-4.1A)
LVY  B1429 (-4.7A)
LVY  B1429 (-4.5A)
LVY  B1429 (-4.0A)
LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.43A 6h0fE-4ci2B:
29.8
6h0fF-4ci2B:
undetectable		 6h0fE-4ci2B:
46.28
6h0fF-4ci2B:
4.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H0F_E_Y70E502_0
(IKAROS (IKZF1)
PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		6 / 12 GLU B 379
HIS B 380
TRP B 382
TRP B 388
TRP B 402
PHE B 404
 None
LVY  B1429 (-4.0A)
LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.95A 6h0fE-4ci2B:
29.8
6h0fF-4ci2B:
undetectable		 6h0fE-4ci2B:
46.28
6h0fF-4ci2B:
4.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H0F_H_Y70H502_0
(IKAROS (IKZF1)
PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		8 / 12 ASN B 353
PRO B 354
HIS B 355
HIS B 380
TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-4.1A)
LVY  B1429 (-4.7A)
LVY  B1429 (-4.5A)
LVY  B1429 (-4.0A)
LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.42A 6h0fH-4ci2B:
29.9
6h0fI-4ci2B:
undetectable		 6h0fH-4ci2B:
46.28
6h0fI-4ci2B:
4.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H0F_H_Y70H502_0
(IKAROS (IKZF1)
PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		6 / 12 GLU B 379
HIS B 380
TRP B 382
TRP B 388
TRP B 402
PHE B 404
 None
LVY  B1429 (-4.0A)
LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.93A 6h0fH-4ci2B:
29.9
6h0fI-4ci2B:
undetectable		 6h0fH-4ci2B:
46.28
6h0fI-4ci2B:
4.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H0F_K_Y70K502_0
(IKAROS (IKZF1)
PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		8 / 12 ASN B 353
PRO B 354
HIS B 355
HIS B 380
TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-4.1A)
LVY  B1429 (-4.7A)
LVY  B1429 (-4.5A)
LVY  B1429 (-4.0A)
LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.43A 6h0fK-4ci2B:
29.7
6h0fL-4ci2B:
undetectable		 6h0fK-4ci2B:
46.28
6h0fL-4ci2B:
4.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H0F_K_Y70K502_0
(IKAROS (IKZF1)
PROTEIN CEREBLON)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		6 / 12 GLU B 379
HIS B 380
TRP B 382
TRP B 388
TRP B 402
PHE B 404
 None
LVY  B1429 (-4.0A)
LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.95A 6h0fK-4ci2B:
29.7
6h0fL-4ci2B:
undetectable		 6h0fK-4ci2B:
46.28
6h0fL-4ci2B:
4.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H0G_B_Y70B502_0
(PROTEIN CEREBLON
ZINC FINGER PROTEIN
692)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		8 / 11 ASN B 353
PRO B 354
HIS B 355
HIS B 380
TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-4.1A)
LVY  B1429 (-4.7A)
LVY  B1429 (-4.5A)
LVY  B1429 (-4.0A)
LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.45A 6h0gB-4ci2B:
50.7
6h0gC-4ci2B:
undetectable		 6h0gB-4ci2B:
46.28
6h0gC-4ci2B:
8.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H0G_E_Y70E502_0
(PROTEIN CEREBLON
ZINC FINGER PROTEIN
692)		 4ci2 PROTEIN CEREBLON
(Gallus
gallus) 		9 / 12 ASN B 353
PRO B 354
HIS B 355
HIS B 380
SER B 381
TRP B 382
TRP B 388
TRP B 402
PHE B 404
 LVY  B1429 (-4.1A)
LVY  B1429 (-4.7A)
LVY  B1429 (-4.5A)
LVY  B1429 (-4.0A)
LVY  B1429 (-3.8A)
LVY  B1429 (-3.1A)
LVY  B1429 (-3.5A)
LVY  B1429 (-3.7A)
LVY  B1429 (-4.5A)
 0.34A 6h0gE-4ci2B:
50.4
6h0gF-4ci2B:
undetectable		 6h0gE-4ci2B:
46.28
6h0gF-4ci2B:
8.91