SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ci6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMI_A_BHSA1610_1
(NITRIC OXIDE
SYNTHASE)		 4ci6 PROTEIN KINASE YOPO
(Yersinia
enterocolitica) 		4 / 8 SER B 628
ALA B 630
TRP B 629
PHE B 683
 None
 0.99A 1dmiA-4ci6B:
undetectable
1dmiB-4ci6B:
undetectable		 1dmiA-4ci6B:
22.46
1dmiB-4ci6B:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OSV_B_CHCB201_2
(BILE ACID RECEPTOR)		 4ci6 PROTEIN KINASE YOPO
(Yersinia
enterocolitica) 		4 / 5 HIS B 179
ARG B 292
ILE B 268
HIS B 257
 None
 1.21A 1osvB-4ci6B:
undetectable		 1osvB-4ci6B:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9Q_A_CHDA459_0
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 4ci6 PROTEIN KINASE YOPO
(Yersinia
enterocolitica) 		4 / 6 ASP B 212
LEU B 157
VAL B 158
ILE B 147
 None
 0.93A 1s9qA-4ci6B:
undetectable		 1s9qA-4ci6B:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DPZ_A_TYLA2001_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 4ci6 PROTEIN KINASE YOPO
(Yersinia
enterocolitica) 		4 / 6 LEU B 190
ALA B 176
HIS B 265
ASP B 321
 None
 1.30A 2dpzA-4ci6B:
undetectable		 2dpzA-4ci6B:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OUZ_A_C3DA999_0
(ESTROGEN RECEPTOR)		 4ci6 PROTEIN KINASE YOPO
(Yersinia
enterocolitica) 		5 / 12 LEU B 252
LEU B 251
ILE B 385
HIS B 402
LEU B 405
 None
 0.99A 2ouzA-4ci6B:
undetectable		 2ouzA-4ci6B:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_A_CHDA502_0
(FERROCHELATASE)		 4ci6 PROTEIN KINASE YOPO
(Yersinia
enterocolitica) 		4 / 8 PRO B 297
SER B 291
VAL B 311
GLY B 312
 None
 1.02A 2qd3A-4ci6B:
undetectable		 2qd3A-4ci6B:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		 4ci6 PROTEIN KINASE YOPO
(Yersinia
enterocolitica) 		4 / 6 ILE B 247
ARG B 250
LEU B 251
LEU B 419
 None
 0.71A 2rlfA-4ci6B:
undetectable
2rlfD-4ci6B:
undetectable		 2rlfA-4ci6B:
5.41
2rlfD-4ci6B:
5.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L4D_D_TPFD490_1
(STEROL 14-ALPHA
DEMETHYLASE)		 4ci6 PROTEIN KINASE YOPO
(Yersinia
enterocolitica) 		4 / 8 PHE B 404
TYR B 378
ALA B 248
LEU B 223
 None
 1.04A 3l4dD-4ci6B:
2.8		 3l4dD-4ci6B:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL6_A_NIMA614_1
(LACTOPEROXIDASE)		 4ci6 PROTEIN KINASE YOPO
(Yersinia
enterocolitica) 		4 / 7 HIS B 249
GLU B 318
ARG B 400
PRO B 394
 None
 1.26A 3ql6A-4ci6B:
undetectable		 3ql6A-4ci6B:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WAR_A_NIOA401_1
(CASEIN KINASE II
SUBUNIT ALPHA)		 4ci6 PROTEIN KINASE YOPO
(Yersinia
enterocolitica) 		4 / 8 VAL B 158
LYS B 160
ILE B 285
ASP B 286
 None
 0.71A 3warA-4ci6B:
18.0		 3warA-4ci6B:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1W_A_STRA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 4ci6 PROTEIN KINASE YOPO
(Yersinia
enterocolitica) 		4 / 7 TYR B 181
VAL B 284
ILE B 285
LEU B 209
 None
 1.01A 4l1wA-4ci6B:
undetectable		 4l1wA-4ci6B:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L3G_F_ACTF401_0
(METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN)		 4ci6 PROTEIN KINASE YOPO
(Yersinia
enterocolitica) 		3 / 3 ARG B 720
LEU B 724
GLU B 727
 None
 0.62A 4l3gF-4ci6B:
undetectable		 4l3gF-4ci6B:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4ci6 PROTEIN KINASE YOPO
(Yersinia
enterocolitica) 		4 / 8 PRO B 297
SER B 291
VAL B 311
GLY B 312
 None
 1.03A 4mk4A-4ci6B:
undetectable		 4mk4A-4ci6B:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_C_ADNC501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 4ci6 PROTEIN KINASE YOPO
(Yersinia
enterocolitica) 		5 / 12 VAL B 572
SER B 468
LEU B 461
GLY B 464
ASP B 469
 None
 1.48A 4pevC-4ci6B:
undetectable		 4pevC-4ci6B:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BOJ_A_4TXA201_1
(TRANSTHYRETIN)		 4ci6 PROTEIN KINASE YOPO
(Yersinia
enterocolitica) 		4 / 6 LEU B 608
LEU B 605
SER B 602
THR B 600
 None
 1.03A 5bojA-4ci6B:
undetectable		 5bojA-4ci6B:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWZ_B_BEZB301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 4ci6 PROTEIN KINASE YOPO
(Yersinia
enterocolitica) 		3 / 3 MET B 661
GLN B 660
ARG B 659
 None
 0.92A 5ewzB-4ci6B:
7.0		 5ewzB-4ci6B:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M35_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 4ci6 PROTEIN KINASE YOPO
(Yersinia
enterocolitica) 		3 / 3 MET B 661
GLN B 660
ARG B 659
 None
 0.82A 5m35B-4ci6B:
6.6		 5m35B-4ci6B:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M36_A_BEZA303_0
(14-3-3 PROTEIN
ZETA/DELTA)		 4ci6 PROTEIN KINASE YOPO
(Yersinia
enterocolitica) 		3 / 3 MET B 661
GLN B 660
ARG B 659
 None
 0.80A 5m36A-4ci6B:
4.4		 5m36A-4ci6B:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4ci6 PROTEIN KINASE YOPO
(Yersinia
enterocolitica) 		4 / 8 HIS B 563
LEU B 566
VAL B 599
SER B 602
 None
 1.03A 5m8rC-4ci6B:
undetectable		 5m8rC-4ci6B:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_D_MMSD509_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4ci6 PROTEIN KINASE YOPO
(Yersinia
enterocolitica) 		4 / 8 HIS B 563
LEU B 566
VAL B 599
SER B 602
 None
 1.01A 5m8rD-4ci6B:
undetectable		 5m8rD-4ci6B:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1808_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 4ci6 PROTEIN KINASE YOPO
(Yersinia
enterocolitica) 		4 / 5 LYS B 245
ALA B 248
LEU B 251
LEU B 405
 None
 0.70A 5vkqA-4ci6B:
4.0
5vkqD-4ci6B:
4.1		 5vkqA-4ci6B:
17.29
5vkqD-4ci6B:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 4ci6 PROTEIN KINASE YOPO
(Yersinia
enterocolitica) 		4 / 5 LEU B 405
LYS B 245
ALA B 248
LEU B 251
 None
 0.70A 5vkqA-4ci6B:
4.2
5vkqB-4ci6B:
4.2		 5vkqA-4ci6B:
17.29
5vkqB-4ci6B:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 4ci6 PROTEIN KINASE YOPO
(Yersinia
enterocolitica) 		4 / 5 LEU B 405
LYS B 245
ALA B 248
LEU B 251
 None
 0.64A 5vkqB-4ci6B:
4.1
5vkqC-4ci6B:
4.1		 5vkqB-4ci6B:
17.29
5vkqC-4ci6B:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 4ci6 PROTEIN KINASE YOPO
(Yersinia
enterocolitica) 		4 / 5 LEU B 405
LYS B 245
ALA B 248
LEU B 251
 None
 0.74A 5vkqC-4ci6B:
4.1
5vkqD-4ci6B:
4.1		 5vkqC-4ci6B:
17.29
5vkqD-4ci6B:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_A_CVIA301_0
(REGULATORY PROTEIN
TETR)		 4ci6 PROTEIN KINASE YOPO
(Yersinia
enterocolitica) 		5 / 12 ALA B 316
SER B 320
LEU B 324
ILE B 268
TYR B 177
 None
 1.42A 5vlmA-4ci6B:
3.5		 5vlmA-4ci6B:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9M_X_NIOX401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 4ci6 PROTEIN KINASE YOPO
(Yersinia
enterocolitica) 		4 / 8 VAL B 158
LYS B 160
ILE B 285
ASP B 286
 None
 0.64A 5y9mX-4ci6B:
12.0		 5y9mX-4ci6B:
8.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF9_B_NIOB401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 4ci6 PROTEIN KINASE YOPO
(Yersinia
enterocolitica) 		4 / 7 VAL B 158
LYS B 160
ILE B 285
ASP B 286
 None
 0.65A 5yf9B-4ci6B:
18.0		 5yf9B-4ci6B:
8.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YWM_X_NIOX403_0
(CASEIN KINASE II
SUBUNIT ALPHA')		 4ci6 PROTEIN KINASE YOPO
(Yersinia
enterocolitica) 		4 / 7 VAL B 158
LYS B 160
ILE B 285
ASP B 286
 None
 0.69A 5ywmX-4ci6B:
18.2		 5ywmX-4ci6B:
8.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0L_B_TA1B502_1
(TUBULIN BETA CHAIN)		 4ci6 PROTEIN KINASE YOPO
(Yersinia
enterocolitica) 		5 / 12 LEU B 252
HIS B 402
LEU B 405
GLY B 387
LEU B 386
 None
 1.06A 6b0lB-4ci6B:
undetectable		 6b0lB-4ci6B:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FN9_A_BEZA302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 4ci6 PROTEIN KINASE YOPO
(Yersinia
enterocolitica) 		3 / 3 MET B 661
GLN B 660
ARG B 659
 None
 0.83A 6fn9A-4ci6B:
6.5		 6fn9A-4ci6B:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNA_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 4ci6 PROTEIN KINASE YOPO
(Yersinia
enterocolitica) 		3 / 3 MET B 661
GLN B 660
ARG B 659
 None
 0.81A 6fnaB-4ci6B:
6.5		 6fnaB-4ci6B:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNB_A_BEZA301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 4ci6 PROTEIN KINASE YOPO
(Yersinia
enterocolitica) 		3 / 3 MET B 661
GLN B 660
ARG B 659
 None
 0.83A 6fnbA-4ci6B:
6.5		 6fnbA-4ci6B:
20.00