SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ckb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1A27_A_ESTA350_1 (17-BETA-HYDROXYSTERO ID-DEHYDROGENASE)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	5 / 12	GLY A 283 LEU A 282 TYR A 278 VAL A 468 MET A 221	None	1.49A	1a27A-4ckbA: 7.6	1a27A-4ckbA: 15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1A4G_A_ZMRA466_1 (NEURAMINIDASE)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	5 / 12	ARG A 655 ASP A 598 GLU A 652 ALA A 625 ARG A 548	SAH A1845 (-3.3A) SAH A1845 (-3.5A) None SAH A1845 ( 4.7A) SAH A1845 (-3.4A)	1.40A	1a4gA-4ckbA: undetectable	1a4gA-4ckbA: 19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DFO_A_FFOA1002_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	4 / 5	TYR A 457 TYR A 164 PHE A 407 PRO A 414	None	1.23A	1dfoB-4ckbA: undetectable	1dfoB-4ckbA: 19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DFO_B_FFOB2002_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	4 / 5	TYR A 457 TYR A 164 PHE A 407 PRO A 414	None	1.24A	1dfoA-4ckbA: undetectable	1dfoA-4ckbA: 19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DFO_C_FFOC3002_2 (SERINE HYDROXYMETHYLTRANSFE RASE)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	4 / 5	TYR A 457 TYR A 164 PHE A 407 PRO A 414	None	1.23A	1dfoD-4ckbA: undetectable	1dfoD-4ckbA: 19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DFO_D_FFOD4002_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	4 / 5	TYR A 457 TYR A 164 PHE A 407 PRO A 414	None	1.23A	1dfoC-4ckbA: 2.0	1dfoC-4ckbA: 19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DMI_A_BHSA1610_1 (NITRIC OXIDE SYNTHASE)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	4 / 8	VAL A 203 ALA A 19 PHE A 156 GLU A 207	None	1.07A	1dmiA-4ckbA: undetectable 1dmiB-4ckbA: undetectable	1dmiA-4ckbA: 19.91 1dmiB-4ckbA: 19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FM4_A_DXCA1002_0 (MAJOR POLLEN ALLERGEN BET V 1-L)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	5 / 12	ILE A 219 TYR A 284 VAL A 227 ILE A 286 TYR A 288	None	1.24A	1fm4A-4ckbA: undetectable	1fm4A-4ckbA: 10.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FM6_D_BRLD503_2 (PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	4 / 4	ILE A 341 LEU A 314 VAL A 300 ILE A 268	None	0.83A	1fm6D-4ckbA: undetectable	1fm6D-4ckbA: 15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HXB_A_ROCA100_2 (HIV-1 PROTEASE)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	3 / 3	ARG A 548 THR A 759 VAL A 553	SAH A1845 (-3.4A) None None	0.95A	1hxbA-4ckbA: undetectable	1hxbA-4ckbA: 8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HZE_A_RBFA98_1 (RIBOFLAVIN SYNTHASE ALPHA CHAIN)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	5 / 9	LEU A 115 LEU A 121 ILE A 193 THR A 10 ILE A 11	None	1.36A	1hzeA-4ckbA: undetectable 1hzeB-4ckbA: undetectable	1hzeA-4ckbA: 8.32 1hzeB-4ckbA: 8.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HZE_B_RBFB99_1 (RIBOFLAVIN SYNTHASE ALPHA CHAIN)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	5 / 9	THR A 10 ILE A 11 LEU A 115 LEU A 121 ILE A 193	None	1.35A	1hzeA-4ckbA: undetectable 1hzeB-4ckbA: undetectable	1hzeA-4ckbA: 8.32 1hzeB-4ckbA: 8.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1I18_B_RBFB99_1 (RIBOFLAVIN SYNTHASE ALPHA CHAIN)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	5 / 10	THR A 10 ILE A 11 LEU A 115 LEU A 121 ILE A 193	None	1.39A	1i18A-4ckbA: undetectable 1i18B-4ckbA: undetectable	1i18A-4ckbA: 8.32 1i18B-4ckbA: 8.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1N2X_A_SAMA401_0 (S-ADENOSYL-METHYLTRA NSFERASE MRAW)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	5 / 12	THR A 280 GLU A 467 VAL A 468 TYR A 278 ARG A 493	None	1.20A	1n2xA-4ckbA: 14.8	1n2xA-4ckbA: 15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QZR_B_CDXB901_1 (DNA TOPOISOMERASE II)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	4 / 7	THR A 13 TYR A 14 ASN A 113 LEU A 40	None	0.75A	1qzrA-4ckbA: undetectable	1qzrA-4ckbA: 20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QZR_B_CDXB901_2 (DNA TOPOISOMERASE II)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	4 / 7	THR A 13 TYR A 14 ASN A 113 LEU A 40	None	0.61A	1qzrB-4ckbA: undetectable	1qzrB-4ckbA: 20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RI4_A_SAMA299_0 (MRNA CAPPING ENZYME)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	5 / 12	LYS A 573 GLY A 600 GLN A 678 PHE A 679 TYR A 683	SAH A1845 (-2.8A) SAH A1845 (-3.4A) None None SAH A1845 (-3.5A)	0.38A	1ri4A-4ckbA: 27.5	1ri4A-4ckbA: 16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CML_A_ZMRA1477_1 (NEURAMINIDASE)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	5 / 12	ARG A 655 ASP A 598 GLU A 652 ALA A 625 ARG A 548	SAH A1845 (-3.3A) SAH A1845 (-3.5A) None SAH A1845 ( 4.7A) SAH A1845 (-3.4A)	1.47A	2cmlA-4ckbA: undetectable	2cmlA-4ckbA: 19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CML_B_ZMRB2477_1 (NEURAMINIDASE)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	5 / 12	ARG A 655 ASP A 598 GLU A 652 ALA A 625 ARG A 548	SAH A1845 (-3.3A) SAH A1845 (-3.5A) None SAH A1845 ( 4.7A) SAH A1845 (-3.4A)	1.46A	2cmlB-4ckbA: undetectable	2cmlB-4ckbA: 19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CML_C_ZMRC3477_1 (NEURAMINIDASE)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	5 / 12	ARG A 655 ASP A 598 GLU A 652 ALA A 625 ARG A 548	SAH A1845 (-3.3A) SAH A1845 (-3.5A) None SAH A1845 ( 4.7A) SAH A1845 (-3.4A)	1.48A	2cmlC-4ckbA: undetectable	2cmlC-4ckbA: 19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CML_D_ZMRD4477_1 (NEURAMINIDASE)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	5 / 12	ARG A 655 ASP A 598 GLU A 652 ALA A 625 ARG A 548	SAH A1845 (-3.3A) SAH A1845 (-3.5A) None SAH A1845 ( 4.7A) SAH A1845 (-3.4A)	1.48A	2cmlD-4ckbA: undetectable	2cmlD-4ckbA: 19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2GLU_B_SAMB302_0 (YCGJ)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	5 / 12	GLY A 600 GLY A 602 ALA A 618 THR A 619 ALA A 625	SAH A1845 (-3.4A) None None None SAH A1845 ( 4.7A)	1.03A	2gluB-4ckbA: 15.6	2gluB-4ckbA: 12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HTU_A_BCZA801_1 (NEURAMINIDASE)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	4 / 4	ARG A 655 ASP A 598 GLU A 652 ARG A 548	SAH A1845 (-3.3A) SAH A1845 (-3.5A) None SAH A1845 (-3.4A)	1.42A	2htuA-4ckbA: undetectable	2htuA-4ckbA: 17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HYY_B_STIB600_2 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	4 / 6	LEU A 88 VAL A 445 VAL A 405 ILE A 415	None	1.09A	2hyyB-4ckbA: undetectable	2hyyB-4ckbA: 15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2J0D_A_ERYA1498_0 (CYTOCHROME P450 3A4)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	5 / 12	PHE A 42 SER A 216 ILE A 11 ILE A 15 ALA A 151	None	1.12A	2j0dA-4ckbA: undetectable	2j0dA-4ckbA: 21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V0M_B_KLNB1499_1 (CYTOCHROME P450 3A4)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	4 / 7	PHE A 240 PHE A 685 ILE A 681 ILE A 597	None	0.95A	2v0mB-4ckbA: undetectable	2v0mB-4ckbA: 21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VMY_A_FFOA505_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	4 / 6	TYR A 457 TYR A 164 PHE A 407 PRO A 414	None	1.25A	2vmyA-4ckbA: undetectable	2vmyA-4ckbA: 19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3D4S_A_TIMA401_2 (BETA-2 ADRENERGIC RECEPTOR/T4-LYSOZYME CHIMERA)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	3 / 3	THR A 13 SER A 9 PHE A 220	None	0.60A	3d4sA-4ckbA: undetectable	3d4sA-4ckbA: 20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3K37_B_BCZB468_0 (NEURAMINIDASE)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	5 / 12	ARG A 655 ASP A 598 GLU A 652 ALA A 625 ARG A 548	SAH A1845 (-3.3A) SAH A1845 (-3.5A) None SAH A1845 ( 4.7A) SAH A1845 (-3.4A)	1.43A	3k37B-4ckbA: undetectable	3k37B-4ckbA: 17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3K5V_A_STIA2_2 (TYROSINE-PROTEIN KINASE ABL1)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	4 / 6	LEU A 88 VAL A 445 VAL A 405 ILE A 415	None	1.15A	3k5vA-4ckbA: undetectable	3k5vA-4ckbA: 16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3K5V_B_STIB2_2 (TYROSINE-PROTEIN KINASE ABL1)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	4 / 6	LEU A 88 VAL A 445 VAL A 405 ILE A 415	None	1.15A	3k5vB-4ckbA: undetectable	3k5vB-4ckbA: 16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LXI_B_CAMB423_0 (CYTOCHROME P450)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	5 / 11	LEU A 250 GLY A 249 THR A 359 VAL A 363 VAL A 362	None	1.18A	3lxiB-4ckbA: undetectable	3lxiB-4ckbA: 18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3Q5R_A_KANA2002_1 (MULTIDRUG-EFFLUX TRANSPORTER 1 REGULATOR)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	5 / 11	PRO A 476 VAL A 474 ASN A 55 ILE A 477 ILE A 149	None	1.48A	3q5rA-4ckbA: undetectable	3q5rA-4ckbA: 16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TIC_A_ZMRA1002_1 (NEURAMINIDASE)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	5 / 12	ARG A 655 ASP A 598 GLU A 652 ALA A 625 ARG A 548	SAH A1845 (-3.3A) SAH A1845 (-3.5A) None SAH A1845 ( 4.7A) SAH A1845 (-3.4A)	1.44A	3ticA-4ckbA: undetectable	3ticA-4ckbA: 20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TIC_B_ZMRB1002_1 (NEURAMINIDASE)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	5 / 12	ARG A 655 ASP A 598 GLU A 652 ALA A 625 ARG A 548	SAH A1845 (-3.3A) SAH A1845 (-3.5A) None SAH A1845 ( 4.7A) SAH A1845 (-3.4A)	1.45A	3ticB-4ckbA: undetectable	3ticB-4ckbA: 20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TIC_C_ZMRC1002_1 (NEURAMINIDASE)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	5 / 12	ARG A 655 ASP A 598 GLU A 652 ALA A 625 ARG A 548	SAH A1845 (-3.3A) SAH A1845 (-3.5A) None SAH A1845 ( 4.7A) SAH A1845 (-3.4A)	1.45A	3ticC-4ckbA: undetectable	3ticC-4ckbA: 20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TIC_D_ZMRD1002_1 (NEURAMINIDASE)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	5 / 12	ARG A 655 ASP A 598 GLU A 652 ALA A 625 ARG A 548	SAH A1845 (-3.3A) SAH A1845 (-3.5A) None SAH A1845 ( 4.7A) SAH A1845 (-3.4A)	1.45A	3ticD-4ckbA: undetectable	3ticD-4ckbA: 20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TJ7_C_ACTC608_0 (GBAA_1210 PROTEIN)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	4 / 5	GLU A 39 ARG A 77 LYS A 161 GLU A 194	None	1.36A	3tj7C-4ckbA: 7.7	3tj7C-4ckbA: 12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CPN_A_ZMRA700_1 (NEURAMINIDASE)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	5 / 12	ARG A 655 ASP A 598 GLU A 652 ALA A 625 ARG A 548	SAH A1845 (-3.3A) SAH A1845 (-3.5A) None SAH A1845 ( 4.7A) SAH A1845 (-3.4A)	1.35A	4cpnA-4ckbA: undetectable	4cpnA-4ckbA: 20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CPN_B_ZMRB700_1 (NEURAMINIDASE)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	5 / 12	ARG A 655 ASP A 598 GLU A 652 ALA A 625 ARG A 548	SAH A1845 (-3.3A) SAH A1845 (-3.5A) None SAH A1845 ( 4.7A) SAH A1845 (-3.4A)	1.43A	4cpnB-4ckbA: undetectable	4cpnB-4ckbA: 20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CPZ_C_ZMRC1470_1 (NEURAMINIDASE)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	5 / 12	ARG A 655 ASP A 598 GLU A 652 ALA A 625 ARG A 548	SAH A1845 (-3.3A) SAH A1845 (-3.5A) None SAH A1845 ( 4.7A) SAH A1845 (-3.4A)	1.38A	4cpzC-4ckbA: undetectable	4cpzC-4ckbA: 20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CPZ_E_ZMRE1471_1 (NEURAMINIDASE)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	5 / 12	ARG A 655 ASP A 598 GLU A 652 ALA A 625 ARG A 548	SAH A1845 (-3.3A) SAH A1845 (-3.5A) None SAH A1845 ( 4.7A) SAH A1845 (-3.4A)	1.41A	4cpzE-4ckbA: undetectable	4cpzE-4ckbA: 20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CPZ_F_ZMRF1470_1 (NEURAMINIDASE)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	5 / 12	ARG A 655 ASP A 598 GLU A 652 ALA A 625 ARG A 548	SAH A1845 (-3.3A) SAH A1845 (-3.5A) None SAH A1845 ( 4.7A) SAH A1845 (-3.4A)	1.42A	4cpzF-4ckbA: undetectable	4cpzF-4ckbA: 20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CPZ_G_ZMRG1471_1 (NEURAMINIDASE)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	5 / 12	ARG A 655 ASP A 598 GLU A 652 ALA A 625 ARG A 548	SAH A1845 (-3.3A) SAH A1845 (-3.5A) None SAH A1845 ( 4.7A) SAH A1845 (-3.4A)	1.40A	4cpzG-4ckbA: undetectable	4cpzG-4ckbA: 20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CPZ_H_ZMRH1470_1 (NEURAMINIDASE)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	5 / 12	ARG A 655 ASP A 598 GLU A 652 ALA A 625 ARG A 548	SAH A1845 (-3.3A) SAH A1845 (-3.5A) None SAH A1845 ( 4.7A) SAH A1845 (-3.4A)	1.41A	4cpzH-4ckbA: undetectable	4cpzH-4ckbA: 20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4I13_A_FOLA201_1 (DIHYDROFOLATE REDUCTASE)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	3 / 3	ASP A 545 ARG A 748 THR A 653	None	0.86A	4i13A-4ckbA: 2.8	4i13A-4ckbA: 9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JQ4_B_IMNB401_1 (ALDO-KETO REDUCTASE FAMILY 1 MEMBER C2)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	5 / 10	TYR A 452 VAL A 54 ILE A 149 LEU A 145 LEU A 162	None	1.49A	4jq4B-4ckbA: undetectable	4jq4B-4ckbA: 16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M6T_A_SAMA201_0 (RNA POLYMERASE II-ASSOCIATED FACTOR 1 HOMOLOG, LINKER, RNA POLYMERASE-ASSOCIATE D PROTEIN LEO1)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	4 / 4	ILE A 613 VAL A 617 VAL A 594 ARG A 592	None	1.26A	4m6tA-4ckbA: undetectable	4m6tA-4ckbA: 12.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4P3R_A_FOLA201_1 (DIHYDROFOLATE REDUCTASE)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	3 / 3	ASP A 545 ARG A 748 THR A 653	None	0.87A	4p3rA-4ckbA: undetectable	4p3rA-4ckbA: 9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PFJ_A_ADNA502_2 (ADENOSYLHOMOCYSTEINA SE)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	4 / 7	THR A 756 HIS A 682 ASN A 550 SER A 740	None None SAH A1845 (-4.1A) None	0.97A	4pfjA-4ckbA: 5.2	4pfjA-4ckbA: 18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4POO_B_SAMB301_0 (PUTATIVE RNA METHYLASE)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	5 / 12	GLY A 600 ASN A 601 ASP A 604 ASP A 620 SER A 684	SAH A1845 (-3.4A) None SAH A1845 ( 4.2A) SAH A1845 (-2.7A) SAH A1845 ( 4.8A)	0.93A	4pooB-4ckbA: 13.2	4pooB-4ckbA: 13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZZB_C_ACTC401_0 (PROTON-GATED ION CHANNEL)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	4 / 7	ILE A 266 PHE A 279 VAL A 312 ILE A 345	None	0.96A	4zzbC-4ckbA: undetectable 4zzbD-4ckbA: undetectable	4zzbC-4ckbA: 17.79 4zzbD-4ckbA: 17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LG3_J_Z80J401_1 (GAMMA-AMINOBUTYRIC-A CID RECEPTOR SUBUNIT BETA-1)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	5 / 12	ILE A 444 VAL A 424 GLU A 413 ASN A 455 ILE A 477	None	0.95A	5lg3J-4ckbA: undetectable	5lg3J-4ckbA: 15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ODH_G_ACTG710_0 (HETERODISULFIDE REDUCTASE, SUBUNIT A)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	4 / 4	ARG A 592 ILE A 613 TYR A 608 ILE A 577	None	1.17A	5odhG-4ckbA: undetectable	5odhG-4ckbA: 23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5V5Z_A_1YNA602_2 (LANOSTEROL 14-ALPHA DEMETHYLASE)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	3 / 3	GLY A 434 THR A 756 PRO A 760	None	0.53A	5v5zA-4ckbA: undetectable	5v5zA-4ckbA: 21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CDU_G_EY4G501_0 (CHIMERIC ALPHA1GABAA RECEPTOR)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	4 / 7	ILE A 149 GLN A 60 ILE A 158 THR A 153	None	0.84A	6cduF-4ckbA: undetectable 6cduG-4ckbA: undetectable	6cduF-4ckbA: 18.95 6cduG-4ckbA: 18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EBP_A_DAHA123_0 (RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE, BETA SUBUNIT)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	5 / 9	LEU A 700 THR A 701 PHE A 780 PHE A 659 ILE A 597	None	1.17A	6ebpA-4ckbA: undetectable	6ebpA-4ckbA: 6.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EBP_B_DAHB123_0 (RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE, BETA SUBUNIT)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	5 / 10	LEU A 700 THR A 701 PHE A 780 PHE A 659 ILE A 597	None	1.18A	6ebpB-4ckbA: undetectable	6ebpB-4ckbA: 6.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EBZ_A_DAHA123_0 (RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE, BETA SUBUNIT)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	6 / 11	LEU A 700 THR A 701 PHE A 780 PHE A 659 ILE A 654 ILE A 597	None	1.14A	6ebzA-4ckbA: undetectable	6ebzA-4ckbA: 6.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EBZ_B_DAHB123_0 (RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE, BETA SUBUNIT)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	6 / 11	LEU A 700 THR A 701 PHE A 780 PHE A 659 ILE A 654 ILE A 597	None	1.18A	6ebzB-4ckbA: undetectable	6ebzB-4ckbA: 6.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EBZ_C_DAHC123_0 (RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE, BETA SUBUNIT)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	6 / 11	LEU A 700 THR A 701 PHE A 780 PHE A 659 ILE A 654 ILE A 597	None	1.18A	6ebzC-4ckbA: undetectable	6ebzC-4ckbA: 6.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EBZ_D_DAHD123_0 (RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE, BETA SUBUNIT)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	6 / 11	LEU A 700 THR A 701 PHE A 780 PHE A 659 ILE A 654 ILE A 597	None	1.14A	6ebzD-4ckbA: undetectable	6ebzD-4ckbA: 6.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6F88_B_STRB502_1 (CYTOCHROME P450 CYP260A1)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	4 / 6	LEU A 18 ALA A 22 LEU A 215 THR A 153	None	0.97A	6f88B-4ckbA: undetectable	6f88B-4ckbA: 6.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FDY_U_DB8U302_1 (-)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	5 / 9	LEU A 252 VAL A 362 PHE A 391 LEU A 242 ILE A 247	None	1.37A	6fdyU-4ckbA: undetectable	6fdyU-4ckbA: 15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GP2_A_DAHA126_0 (RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE BETA CHAIN)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	6 / 11	LEU A 700 THR A 701 PHE A 780 PHE A 659 ILE A 654 ILE A 597	None	1.13A	6gp2A-4ckbA: undetectable	6gp2A-4ckbA: 7.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GP2_B_DAHB126_0 (RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE BETA CHAIN)	4ckb	MRNA-CAPPING ENZYME CATALYTIC SUBUNIT (Vaccinia virus)	6 / 11	LEU A 700 THR A 701 PHE A 780 PHE A 659 ILE A 654 ILE A 597	None	1.14A	6gp2B-4ckbA: undetectable	6gp2B-4ckbA: 7.10

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1A27_A_ESTA350_1","17-BETA-HYDROXYSTEROID-DEHYDROGENASE","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",5,"GLY A 283;LEU A 282;TYR A 278;VAL A 468;MET A 221","None","1.49A","1a27A-4ckbA:7.6","1a27A-4ckbA:15.17"],["1A4G_A_ZMRA466_1","NEURAMINIDASE","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",5,"ARG A 655;ASP A 598;GLU A 652;ALA A 625;ARG A 548","SAH A1845 (-3.3A);SAH A1845 (-3.5A);None;SAH A1845 ( 4.7A);SAH A1845 (-3.4A)","1.40A","1a4gA-4ckbA:undetectable","1a4gA-4ckbA:19.01"],["1DFO_A_FFOA1002_1","SERINE HYDROXYMETHYLTRANSFERASE","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",4,"TYR A 457;TYR A 164;PHE A 407;PRO A 414","None","1.23A","1dfoB-4ckbA:undetectable","1dfoB-4ckbA:19.32"],["1DFO_B_FFOB2002_0","SERINE HYDROXYMETHYLTRANSFERASE","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",4,"TYR A 457;TYR A 164;PHE A 407;PRO A 414","None","1.24A","1dfoA-4ckbA:undetectable","1dfoA-4ckbA:19.32"],["1DFO_C_FFOC3002_2","SERINE HYDROXYMETHYLTRANSFERASE","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",4,"TYR A 457;TYR A 164;PHE A 407;PRO A 414","None","1.23A","1dfoD-4ckbA:undetectable","1dfoD-4ckbA:19.32"],["1DFO_D_FFOD4002_0","SERINE HYDROXYMETHYLTRANSFERASE","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",4,"TYR A 457;TYR A 164;PHE A 407;PRO A 414","None","1.23A","1dfoC-4ckbA:2.0","1dfoC-4ckbA:19.32"],["1DMI_A_BHSA1610_1","NITRIC OXIDE SYNTHASE;NITRIC OXIDE SYNTHASE","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",4,"VAL A 203;ALA A  19;PHE A 156;GLU A 207","None","1.07A","1dmiA-4ckbA:undetectable;1dmiB-4ckbA:undetectable","1dmiA-4ckbA:19.91;1dmiB-4ckbA:19.91"],["1FM4_A_DXCA1002_0","MAJOR POLLEN ALLERGEN BET V 1-L","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",5,"ILE A 219;TYR A 284;VAL A 227;ILE A 286;TYR A 288","None","1.24A","1fm4A-4ckbA:undetectable","1fm4A-4ckbA:10.97"],["1FM6_D_BRLD503_2","PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",4,"ILE A 341;LEU A 314;VAL A 300;ILE A 268","None","0.83A","1fm6D-4ckbA:undetectable","1fm6D-4ckbA:15.19"],["1HXB_A_ROCA100_2","HIV-1 PROTEASE","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",3,"ARG A 548;THR A 759;VAL A 553","SAH A1845 (-3.4A);None;None","0.95A","1hxbA-4ckbA:undetectable","1hxbA-4ckbA:8.60"],["1HZE_A_RBFA98_1","RIBOFLAVIN SYNTHASE ALPHA CHAIN;RIBOFLAVIN SYNTHASE ALPHA CHAIN","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",5,"LEU A 115;LEU A 121;ILE A 193;THR A  10;ILE A  11","None","1.36A","1hzeA-4ckbA:undetectable;1hzeB-4ckbA:undetectable","1hzeA-4ckbA:8.32;1hzeB-4ckbA:8.32"],["1HZE_B_RBFB99_1","RIBOFLAVIN SYNTHASE ALPHA CHAIN;RIBOFLAVIN SYNTHASE ALPHA CHAIN","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",5,"THR A  10;ILE A  11;LEU A 115;LEU A 121;ILE A 193","None","1.35A","1hzeA-4ckbA:undetectable;1hzeB-4ckbA:undetectable","1hzeA-4ckbA:8.32;1hzeB-4ckbA:8.32"],["1I18_B_RBFB99_1","RIBOFLAVIN SYNTHASE ALPHA CHAIN;RIBOFLAVIN SYNTHASE ALPHA CHAIN","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",5,"THR A  10;ILE A  11;LEU A 115;LEU A 121;ILE A 193","None","1.39A","1i18A-4ckbA:undetectable;1i18B-4ckbA:undetectable","1i18A-4ckbA:8.32;1i18B-4ckbA:8.32"],["1N2X_A_SAMA401_0","S-ADENOSYL-METHYLTRANSFERASE MRAW","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",5,"THR A 280;GLU A 467;VAL A 468;TYR A 278;ARG A 493","None","1.20A","1n2xA-4ckbA:14.8","1n2xA-4ckbA:15.69"],["1QZR_B_CDXB901_1","DNA TOPOISOMERASE II;DNA TOPOISOMERASE II","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",4,"THR A  13;TYR A  14;ASN A 113;LEU A  40","None","0.75A","1qzrA-4ckbA:undetectable","1qzrA-4ckbA:20.99"],["1QZR_B_CDXB901_2","DNA TOPOISOMERASE II","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",4,"THR A  13;TYR A  14;ASN A 113;LEU A  40","None","0.61A","1qzrB-4ckbA:undetectable","1qzrB-4ckbA:20.99"],["1RI4_A_SAMA299_0","MRNA CAPPING ENZYME","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",5,"LYS A 573;GLY A 600;GLN A 678;PHE A 679;TYR A 683","SAH A1845 (-2.8A);SAH A1845 (-3.4A);None;None;SAH A1845 (-3.5A)","0.38A","1ri4A-4ckbA:27.5","1ri4A-4ckbA:16.86"],["2CML_A_ZMRA1477_1","NEURAMINIDASE","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",5,"ARG A 655;ASP A 598;GLU A 652;ALA A 625;ARG A 548","SAH A1845 (-3.3A);SAH A1845 (-3.5A);None;SAH A1845 ( 4.7A);SAH A1845 (-3.4A)","1.47A","2cmlA-4ckbA:undetectable","2cmlA-4ckbA:19.32"],["2CML_B_ZMRB2477_1","NEURAMINIDASE","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",5,"ARG A 655;ASP A 598;GLU A 652;ALA A 625;ARG A 548","SAH A1845 (-3.3A);SAH A1845 (-3.5A);None;SAH A1845 ( 4.7A);SAH A1845 (-3.4A)","1.46A","2cmlB-4ckbA:undetectable","2cmlB-4ckbA:19.32"],["2CML_C_ZMRC3477_1","NEURAMINIDASE","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",5,"ARG A 655;ASP A 598;GLU A 652;ALA A 625;ARG A 548","SAH A1845 (-3.3A);SAH A1845 (-3.5A);None;SAH A1845 ( 4.7A);SAH A1845 (-3.4A)","1.48A","2cmlC-4ckbA:undetectable","2cmlC-4ckbA:19.32"],["2CML_D_ZMRD4477_1","NEURAMINIDASE","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",5,"ARG A 655;ASP A 598;GLU A 652;ALA A 625;ARG A 548","SAH A1845 (-3.3A);SAH A1845 (-3.5A);None;SAH A1845 ( 4.7A);SAH A1845 (-3.4A)","1.48A","2cmlD-4ckbA:undetectable","2cmlD-4ckbA:19.32"],["2GLU_B_SAMB302_0","YCGJ","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",5,"GLY A 600;GLY A 602;ALA A 618;THR A 619;ALA A 625","SAH A1845 (-3.4A);None;None;None;SAH A1845 ( 4.7A)","1.03A","2gluB-4ckbA:15.6","2gluB-4ckbA:12.95"],["2HTU_A_BCZA801_1","NEURAMINIDASE","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",4,"ARG A 655;ASP A 598;GLU A 652;ARG A 548","SAH A1845 (-3.3A);SAH A1845 (-3.5A);None;SAH A1845 (-3.4A)","1.42A","2htuA-4ckbA:undetectable","2htuA-4ckbA:17.08"],["2HYY_B_STIB600_2","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",4,"LEU A  88;VAL A 445;VAL A 405;ILE A 415","None","1.09A","2hyyB-4ckbA:undetectable","2hyyB-4ckbA:15.81"],["2J0D_A_ERYA1498_0","CYTOCHROME P450 3A4","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",5,"PHE A  42;SER A 216;ILE A  11;ILE A  15;ALA A 151","None","1.12A","2j0dA-4ckbA:undetectable","2j0dA-4ckbA:21.13"],["2V0M_B_KLNB1499_1","CYTOCHROME P450 3A4","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",4,"PHE A 240;PHE A 685;ILE A 681;ILE A 597","None","0.95A","2v0mB-4ckbA:undetectable","2v0mB-4ckbA:21.13"],["2VMY_A_FFOA505_0","SERINE HYDROXYMETHYLTRANSFERASE","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",4,"TYR A 457;TYR A 164;PHE A 407;PRO A 414","None","1.25A","2vmyA-4ckbA:undetectable","2vmyA-4ckbA:19.76"],["3D4S_A_TIMA401_2","BETA-2 ADRENERGIC RECEPTOR\/T4-LYSOZYME CHIMERA","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",3,"THR A  13;SER A   9;PHE A 220","None","0.60A","3d4sA-4ckbA:undetectable","3d4sA-4ckbA:20.35"],["3K37_B_BCZB468_0","NEURAMINIDASE","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",5,"ARG A 655;ASP A 598;GLU A 652;ALA A 625;ARG A 548","SAH A1845 (-3.3A);SAH A1845 (-3.5A);None;SAH A1845 ( 4.7A);SAH A1845 (-3.4A)","1.43A","3k37B-4ckbA:undetectable","3k37B-4ckbA:17.94"],["3K5V_A_STIA2_2","TYROSINE-PROTEIN KINASE ABL1","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",4,"LEU A  88;VAL A 445;VAL A 405;ILE A 415","None","1.15A","3k5vA-4ckbA:undetectable","3k5vA-4ckbA:16.47"],["3K5V_B_STIB2_2","TYROSINE-PROTEIN KINASE ABL1","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",4,"LEU A  88;VAL A 445;VAL A 405;ILE A 415","None","1.15A","3k5vB-4ckbA:undetectable","3k5vB-4ckbA:16.47"],["3LXI_B_CAMB423_0","CYTOCHROME P450","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",5,"LEU A 250;GLY A 249;THR A 359;VAL A 363;VAL A 362","None","1.18A","3lxiB-4ckbA:undetectable","3lxiB-4ckbA:18.96"],["3Q5R_A_KANA2002_1","MULTIDRUG-EFFLUX TRANSPORTER 1 REGULATOR","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",5,"PRO A 476;VAL A 474;ASN A  55;ILE A 477;ILE A 149","None","1.48A","3q5rA-4ckbA:undetectable","3q5rA-4ckbA:16.11"],["3TIC_A_ZMRA1002_1","NEURAMINIDASE","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",5,"ARG A 655;ASP A 598;GLU A 652;ALA A 625;ARG A 548","SAH A1845 (-3.3A);SAH A1845 (-3.5A);None;SAH A1845 ( 4.7A);SAH A1845 (-3.4A)","1.44A","3ticA-4ckbA:undetectable","3ticA-4ckbA:20.33"],["3TIC_B_ZMRB1002_1","NEURAMINIDASE","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",5,"ARG A 655;ASP A 598;GLU A 652;ALA A 625;ARG A 548","SAH A1845 (-3.3A);SAH A1845 (-3.5A);None;SAH A1845 ( 4.7A);SAH A1845 (-3.4A)","1.45A","3ticB-4ckbA:undetectable","3ticB-4ckbA:20.33"],["3TIC_C_ZMRC1002_1","NEURAMINIDASE","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",5,"ARG A 655;ASP A 598;GLU A 652;ALA A 625;ARG A 548","SAH A1845 (-3.3A);SAH A1845 (-3.5A);None;SAH A1845 ( 4.7A);SAH A1845 (-3.4A)","1.45A","3ticC-4ckbA:undetectable","3ticC-4ckbA:20.33"],["3TIC_D_ZMRD1002_1","NEURAMINIDASE","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",5,"ARG A 655;ASP A 598;GLU A 652;ALA A 625;ARG A 548","SAH A1845 (-3.3A);SAH A1845 (-3.5A);None;SAH A1845 ( 4.7A);SAH A1845 (-3.4A)","1.45A","3ticD-4ckbA:undetectable","3ticD-4ckbA:20.33"],["3TJ7_C_ACTC608_0","GBAA_1210 PROTEIN","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",4,"GLU A  39;ARG A  77;LYS A 161;GLU A 194","None","1.36A","3tj7C-4ckbA:7.7","3tj7C-4ckbA:12.38"],["4CPN_A_ZMRA700_1","NEURAMINIDASE","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",5,"ARG A 655;ASP A 598;GLU A 652;ALA A 625;ARG A 548","SAH A1845 (-3.3A);SAH A1845 (-3.5A);None;SAH A1845 ( 4.7A);SAH A1845 (-3.4A)","1.35A","4cpnA-4ckbA:undetectable","4cpnA-4ckbA:20.40"],["4CPN_B_ZMRB700_1","NEURAMINIDASE","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",5,"ARG A 655;ASP A 598;GLU A 652;ALA A 625;ARG A 548","SAH A1845 (-3.3A);SAH A1845 (-3.5A);None;SAH A1845 ( 4.7A);SAH A1845 (-3.4A)","1.43A","4cpnB-4ckbA:undetectable","4cpnB-4ckbA:20.40"],["4CPZ_C_ZMRC1470_1","NEURAMINIDASE","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",5,"ARG A 655;ASP A 598;GLU A 652;ALA A 625;ARG A 548","SAH A1845 (-3.3A);SAH A1845 (-3.5A);None;SAH A1845 ( 4.7A);SAH A1845 (-3.4A)","1.38A","4cpzC-4ckbA:undetectable","4cpzC-4ckbA:20.19"],["4CPZ_E_ZMRE1471_1","NEURAMINIDASE","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",5,"ARG A 655;ASP A 598;GLU A 652;ALA A 625;ARG A 548","SAH A1845 (-3.3A);SAH A1845 (-3.5A);None;SAH A1845 ( 4.7A);SAH A1845 (-3.4A)","1.41A","4cpzE-4ckbA:undetectable","4cpzE-4ckbA:20.19"],["4CPZ_F_ZMRF1470_1","NEURAMINIDASE","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",5,"ARG A 655;ASP A 598;GLU A 652;ALA A 625;ARG A 548","SAH A1845 (-3.3A);SAH A1845 (-3.5A);None;SAH A1845 ( 4.7A);SAH A1845 (-3.4A)","1.42A","4cpzF-4ckbA:undetectable","4cpzF-4ckbA:20.19"],["4CPZ_G_ZMRG1471_1","NEURAMINIDASE","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",5,"ARG A 655;ASP A 598;GLU A 652;ALA A 625;ARG A 548","SAH A1845 (-3.3A);SAH A1845 (-3.5A);None;SAH A1845 ( 4.7A);SAH A1845 (-3.4A)","1.40A","4cpzG-4ckbA:undetectable","4cpzG-4ckbA:20.19"],["4CPZ_H_ZMRH1470_1","NEURAMINIDASE","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",5,"ARG A 655;ASP A 598;GLU A 652;ALA A 625;ARG A 548","SAH A1845 (-3.3A);SAH A1845 (-3.5A);None;SAH A1845 ( 4.7A);SAH A1845 (-3.4A)","1.41A","4cpzH-4ckbA:undetectable","4cpzH-4ckbA:20.19"],["4I13_A_FOLA201_1","DIHYDROFOLATE REDUCTASE","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",3,"ASP A 545;ARG A 748;THR A 653","None","0.86A","4i13A-4ckbA:2.8","4i13A-4ckbA:9.95"],["4JQ4_B_IMNB401_1","ALDO-KETO REDUCTASE FAMILY 1 MEMBER C2","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",5,"TYR A 452;VAL A  54;ILE A 149;LEU A 145;LEU A 162","None","1.49A","4jq4B-4ckbA:undetectable","4jq4B-4ckbA:16.80"],["4M6T_A_SAMA201_0","RNA POLYMERASE II-ASSOCIATED FACTOR 1 HOMOLOG, LINKER, RNA POLYMERASE-ASSOCIATED PROTEIN LEO1","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",4,"ILE A 613;VAL A 617;VAL A 594;ARG A 592","None","1.26A","4m6tA-4ckbA:undetectable","4m6tA-4ckbA:12.06"],["4P3R_A_FOLA201_1","DIHYDROFOLATE REDUCTASE","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",3,"ASP A 545;ARG A 748;THR A 653","None","0.87A","4p3rA-4ckbA:undetectable","4p3rA-4ckbA:9.95"],["4PFJ_A_ADNA502_2","ADENOSYLHOMOCYSTEINASE","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",4,"THR A 756;HIS A 682;ASN A 550;SER A 740","None;None;SAH A1845 (-4.1A);None","0.97A","4pfjA-4ckbA:5.2","4pfjA-4ckbA:18.34"],["4POO_B_SAMB301_0","PUTATIVE RNA METHYLASE","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",5,"GLY A 600;ASN A 601;ASP A 604;ASP A 620;SER A 684","SAH A1845 (-3.4A);None;SAH A1845 ( 4.2A);SAH A1845 (-2.7A);SAH A1845 ( 4.8A)","0.93A","4pooB-4ckbA:13.2","4pooB-4ckbA:13.44"],["4ZZB_C_ACTC401_0","PROTON-GATED ION CHANNEL","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",4,"ILE A 266;PHE A 279;VAL A 312;ILE A 345","None","0.96A","4zzbC-4ckbA:undetectable;4zzbD-4ckbA:undetectable","4zzbC-4ckbA:17.79;4zzbD-4ckbA:17.79"],["5LG3_J_Z80J401_1","GAMMA-AMINOBUTYRIC-ACID RECEPTOR SUBUNIT BETA-1","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",5,"ILE A 444;VAL A 424;GLU A 413;ASN A 455;ILE A 477","None","0.95A","5lg3J-4ckbA:undetectable","5lg3J-4ckbA:15.84"],["5ODH_G_ACTG710_0","HETERODISULFIDE REDUCTASE, SUBUNIT A","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",4,"ARG A 592;ILE A 613;TYR A 608;ILE A 577","None","1.17A","5odhG-4ckbA:undetectable","5odhG-4ckbA:23.08"],["5V5Z_A_1YNA602_2","LANOSTEROL 14-ALPHA DEMETHYLASE","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",3,"GLY A 434;THR A 756;PRO A 760","None","0.53A","5v5zA-4ckbA:undetectable","5v5zA-4ckbA:21.43"],["6CDU_G_EY4G501_0","CHIMERIC ALPHA1GABAA RECEPTOR","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",4,"ILE A 149;GLN A  60;ILE A 158;THR A 153","None","0.84A","6cduF-4ckbA:undetectable;6cduG-4ckbA:undetectable","6cduF-4ckbA:18.95;6cduG-4ckbA:18.95"],["6EBP_A_DAHA123_0","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE, BETA SUBUNIT","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",5,"LEU A 700;THR A 701;PHE A 780;PHE A 659;ILE A 597","None","1.17A","6ebpA-4ckbA:undetectable","6ebpA-4ckbA:6.83"],["6EBP_B_DAHB123_0","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE, BETA SUBUNIT","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",5,"LEU A 700;THR A 701;PHE A 780;PHE A 659;ILE A 597","None","1.18A","6ebpB-4ckbA:undetectable","6ebpB-4ckbA:6.83"],["6EBZ_A_DAHA123_0","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE, BETA SUBUNIT","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",6,"LEU A 700;THR A 701;PHE A 780;PHE A 659;ILE A 654;ILE A 597","None","1.14A","6ebzA-4ckbA:undetectable","6ebzA-4ckbA:6.83"],["6EBZ_B_DAHB123_0","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE, BETA SUBUNIT","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",6,"LEU A 700;THR A 701;PHE A 780;PHE A 659;ILE A 654;ILE A 597","None","1.18A","6ebzB-4ckbA:undetectable","6ebzB-4ckbA:6.83"],["6EBZ_C_DAHC123_0","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE, BETA SUBUNIT","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",6,"LEU A 700;THR A 701;PHE A 780;PHE A 659;ILE A 654;ILE A 597","None","1.18A","6ebzC-4ckbA:undetectable","6ebzC-4ckbA:6.83"],["6EBZ_D_DAHD123_0","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE, BETA SUBUNIT","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",6,"LEU A 700;THR A 701;PHE A 780;PHE A 659;ILE A 654;ILE A 597","None","1.14A","6ebzD-4ckbA:undetectable","6ebzD-4ckbA:6.83"],["6F88_B_STRB502_1","CYTOCHROME P450 CYP260A1","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",4,"LEU A  18;ALA A  22;LEU A 215;THR A 153","None","0.97A","6f88B-4ckbA:undetectable","6f88B-4ckbA:6.51"],["6FDY_U_DB8U302_1","-","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",5,"LEU A 252;VAL A 362;PHE A 391;LEU A 242;ILE A 247","None","1.37A","6fdyU-4ckbA:undetectable","6fdyU-4ckbA:15.08"],["6GP2_A_DAHA126_0","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE BETA CHAIN","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",6,"LEU A 700;THR A 701;PHE A 780;PHE A 659;ILE A 654;ILE A 597","None","1.13A","6gp2A-4ckbA:undetectable","6gp2A-4ckbA:7.10"],["6GP2_B_DAHB126_0","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE BETA CHAIN","4ckb","MRNA-CAPPING ENZYME CATALYTIC SUBUNIT","Vaccinia virus",6,"LEU A 700;THR A 701;PHE A 780;PHE A 659;ILE A 654;ILE A 597","None","1.14A","6gp2B-4ckbA:undetectable","6gp2B-4ckbA:7.10"]]