SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ckn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PHG_A_MYTA422_1
(CYTOCHROME P450-CAM)		 4ckn SAS-6
(Leishmania
major) 		5 / 11 LEU A 177
VAL A 157
GLY A 156
THR A 138
ILE A 223
 None
 1.07A 1phgA-4cknA:
undetectable		 1phgA-4cknA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1001_0
(ALDEHYDE
DEHYDROGENASE A)		 4ckn SAS-6
(Leishmania
major) 		4 / 7 LEU A 205
PHE A 209
PHE A 199
ILE A 263
 None
 0.82A 2opxA-4cknA:
undetectable		 2opxA-4cknA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_1
(PHOSPHOLIPASE A2)		 4ckn SAS-6
(Leishmania
major) 		4 / 5 VAL A 159
VAL A 175
THR A 137
THR A 161
 None
 1.15A 3bjwA-4cknA:
undetectable		 3bjwA-4cknA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_A_IXXA609_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		 4ckn SAS-6
(Leishmania
major) 		5 / 7 ILE A 263
VAL A 139
LEU A 232
LEU A 249
LEU A 135
 None
 0.96A 6g9bA-4cknA:
undetectable
6g9bB-4cknA:
undetectable		 6g9bA-4cknA:
14.75
6g9bB-4cknA:
16.67