SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ckt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		 4ckt PIH1
DOMAIN-CONTAINING
PROTEIN 1
(Mus
musculus) 		3 / 3 LEU A 141
LEU A 138
SER A 135
 None
 0.65A 1tlmA-4cktA:
undetectable		 1tlmA-4cktA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TJY_A_BEZA304_0
(4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE)		 4ckt PIH1
DOMAIN-CONTAINING
PROTEIN 1
(Mus
musculus) 		3 / 3 MET A 132
GLU A 140
ARG A 139
 None
 1.05A 5tjyA-4cktA:
undetectable		 5tjyA-4cktA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TJZ_A_BEZA302_0
(4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE)		 4ckt PIH1
DOMAIN-CONTAINING
PROTEIN 1
(Mus
musculus) 		3 / 3 MET A 132
GLU A 140
ARG A 139
 None
 1.08A 5tjzA-4cktA:
undetectable		 5tjzA-4cktA:
20.00