SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ckv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H1X_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 4ckv VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 1
(Homo
sapiens) 		4 / 5 HIS X 214
TYR X 216
PRO X 134
LYS X 132
 None
 1.36A 3h1xA-4ckvX:
undetectable		 3h1xA-4ckvX:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U52_A_CUA515_0
(PHENOL HYDROXYLASE
COMPONENT PHL
PHENOL HYDROXYLASE
COMPONENT PHN)		 4ckv VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 1
(Homo
sapiens) 		3 / 3 HIS X 147
HIS X 223
ILE X 145
 ZN  X1226 (-3.4A)
ZN  X1226 (-3.3A)
None
 0.79A 3u52A-4ckvX:
undetectable
3u52C-4ckvX:
undetectable		 3u52A-4ckvX:
12.74
3u52C-4ckvX:
13.64