SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4clv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		 4clv NICKEL-COBALT-CADMIU
M RESISTANCE PROTEIN
NCCX
(Cupriavidus
metallidurans) 		5 / 8 TYR A 135
LEU A  45
HIS A  38
GLU A  63
HIS A 119
 None
None
ZN  A1146 (-3.4A)
ZN  A1146 (-2.6A)
ZN  A1146 (-3.4A)
 1.49A 2bnnA-4clvA:
undetectable
2bnnB-4clvA:
undetectable		 2bnnA-4clvA:
23.76
2bnnB-4clvA:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_A_ILEA601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4clv NICKEL-COBALT-CADMIU
M RESISTANCE PROTEIN
NCCX
(Cupriavidus
metallidurans) 		4 / 6 ALA A 101
THR A 102
VAL A 105
VAL A  19
 None
 0.88A 5eckA-4clvA:
undetectable		 5eckA-4clvA:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_D_ILED601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4clv NICKEL-COBALT-CADMIU
M RESISTANCE PROTEIN
NCCX
(Cupriavidus
metallidurans) 		4 / 6 ALA A 101
THR A 102
VAL A 105
VAL A  19
 None
 0.89A 5eckD-4clvA:
undetectable		 5eckD-4clvA:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_A_ILEA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4clv NICKEL-COBALT-CADMIU
M RESISTANCE PROTEIN
NCCX
(Cupriavidus
metallidurans) 		4 / 6 ALA A 101
THR A 102
VAL A 105
VAL A  19
 None
 0.73A 5eclA-4clvA:
undetectable		 5eclA-4clvA:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_D_ILED602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4clv NICKEL-COBALT-CADMIU
M RESISTANCE PROTEIN
NCCX
(Cupriavidus
metallidurans) 		4 / 6 ALA A 101
THR A 102
VAL A 105
VAL A  19
 None
 0.75A 5eclD-4clvA:
undetectable		 5eclD-4clvA:
13.58