SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4cmf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		 4cmf AMINOTRANSFERASE
([Nectria]
haematococca) 		4 / 6 PHE A   8
ALA A  12
GLY A  10
TYR A  11
 None
 1.12A 1gfzA-4cmfA:
undetectable		 1gfzA-4cmfA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4cmf AMINOTRANSFERASE
([Nectria]
haematococca) 		4 / 6 PHE A   8
ALA A  12
GLY A  10
TYR A  11
 None
 1.11A 1l7xA-4cmfA:
undetectable		 1l7xA-4cmfA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4cmf AMINOTRANSFERASE
([Nectria]
haematococca) 		4 / 6 PHE A   8
ALA A  12
GLY A  10
TYR A  11
 None
 1.14A 1l7xB-4cmfA:
undetectable		 1l7xB-4cmfA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NHZ_A_486A800_1
(GLUCOCORTICOID
RECEPTOR)		 4cmf AMINOTRANSFERASE
([Nectria]
haematococca) 		5 / 12 LEU A  78
ASN A  76
LEU A 138
MET A 140
LEU A 100
 None
 1.28A 1nhzA-4cmfA:
undetectable		 1nhzA-4cmfA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_A_CTXA11_1
(CES1 PROTEIN)		 4cmf AMINOTRANSFERASE
([Nectria]
haematococca) 		4 / 8 PRO A 201
LEU A 186
GLY A 184
LEU A 203
 None
 0.93A 1ya4A-4cmfA:
undetectable		 1ya4A-4cmfA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB1283_1
(CES1 PROTEIN)		 4cmf AMINOTRANSFERASE
([Nectria]
haematococca) 		4 / 7 PRO A 201
LEU A 186
GLY A 184
LEU A 203
 None
 0.90A 1ya4B-4cmfA:
undetectable		 1ya4B-4cmfA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_D_SAMD301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4cmf AMINOTRANSFERASE
([Nectria]
haematococca) 		3 / 3 ASP A  55
ASP A  48
ASN A 180
 None
 0.83A 2bm9D-4cmfA:
undetectable		 2bm9D-4cmfA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 4cmf AMINOTRANSFERASE
([Nectria]
haematococca) 		5 / 9 LEU A 284
ILE A 269
PHE A 202
LEU A 210
ILE A 260
 None
 1.26A 2f78A-4cmfA:
undetectable		 2f78A-4cmfA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 4cmf AMINOTRANSFERASE
([Nectria]
haematococca) 		5 / 9 LEU A 284
ILE A 269
PHE A 202
LEU A 210
ILE A 260
 None
 1.24A 2f78B-4cmfA:
1.2		 2f78B-4cmfA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I2Z_A_SALA1100_1
(SERUM ALBUMIN)		 4cmf AMINOTRANSFERASE
([Nectria]
haematococca) 		4 / 5 LEU A 284
LEU A 210
ILE A 260
ALA A 163
 None
 0.67A 2i2zA-4cmfA:
undetectable		 2i2zA-4cmfA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADX_B_IMNB3_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4cmf AMINOTRANSFERASE
([Nectria]
haematococca) 		5 / 12 ALA A 266
ILE A 269
LEU A 270
VAL A 242
ILE A 253
 None
 1.00A 3adxB-4cmfA:
undetectable		 3adxB-4cmfA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BCR_A_AZZA940_1
(GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM)		 4cmf AMINOTRANSFERASE
([Nectria]
haematococca) 		4 / 5 PHE A   8
ALA A  12
GLY A  10
TYR A  11
 None
 1.16A 3bcrA-4cmfA:
undetectable		 3bcrA-4cmfA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4cmf AMINOTRANSFERASE
([Nectria]
haematococca) 		4 / 6 PHE A   8
ALA A  12
GLY A  10
TYR A  11
 None
 1.10A 3dd1B-4cmfA:
undetectable		 3dd1B-4cmfA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HZN_D_ACTD229_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4cmf AMINOTRANSFERASE
([Nectria]
haematococca) 		4 / 4 ASP A 223
GLY A 224
LYS A 222
GLU A 268
 None
 1.35A 3hznD-4cmfA:
undetectable		 3hznD-4cmfA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P73_A_ACTA275_0
(MHC RFP-Y CLASS I
ALPHA CHAIN)		 4cmf AMINOTRANSFERASE
([Nectria]
haematococca) 		3 / 3 ILE A 174
VAL A 169
ARG A 168
 None
 0.58A 3p73A-4cmfA:
undetectable		 3p73A-4cmfA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA506_0
(RNA POLYMERASE
3D-POL)		 4cmf AMINOTRANSFERASE
([Nectria]
haematococca) 		3 / 3 VAL A 125
GLY A 127
LYS A 129
 None
 0.77A 4k50A-4cmfA:
undetectable		 4k50A-4cmfA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_E_ACTE504_0
(RNA POLYMERASE
3D-POL)		 4cmf AMINOTRANSFERASE
([Nectria]
haematococca) 		3 / 3 VAL A 125
GLY A 127
LYS A 129
 None
 0.77A 4k50E-4cmfA:
undetectable		 4k50E-4cmfA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI504_0
(RNA POLYMERASE
3D-POL)		 4cmf AMINOTRANSFERASE
([Nectria]
haematococca) 		3 / 3 VAL A 125
GLY A 127
LYS A 129
 None
 0.75A 4k50I-4cmfA:
undetectable		 4k50I-4cmfA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K87_A_ADNA602_1
(PROLINE--TRNA LIGASE)		 4cmf AMINOTRANSFERASE
([Nectria]
haematococca) 		4 / 8 GLY A 157
THR A 156
THR A 283
ARG A 159
 None
 0.82A 4k87A-4cmfA:
undetectable		 4k87A-4cmfA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA602_1
(SERUM ALBUMIN)		 4cmf AMINOTRANSFERASE
([Nectria]
haematococca) 		4 / 6 ARG A  14
ALA A  12
ASP A 111
LYS A   6
 None
 1.10A 4ot2A-4cmfA:
undetectable		 4ot2A-4cmfA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QKN_A_JMSA602_1
(ALPHA-KETOGLUTARATE-
DEPENDENT
DIOXYGENASE FTO)		 4cmf AMINOTRANSFERASE
([Nectria]
haematococca) 		4 / 8 LEU A 220
THR A 228
PRO A 229
LEU A 270
 None
 1.21A 4qknA-4cmfA:
undetectable		 4qknA-4cmfA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4cmf AMINOTRANSFERASE
([Nectria]
haematococca) 		3 / 3 SER A  62
HIS A 309
TYR A 305
 None
 0.97A 5y2tA-4cmfA:
undetectable		 5y2tA-4cmfA:
undetectable