SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4cmh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_A_CLMA1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4cmh HEAVY CHAIN OF
SAR650984-FAB
FRAGMENT
(Mus
musculus) 		5 / 7 GLY B  54
PRO B  53
THR B  58
ILE B  51
GLY B  56
 None
 1.09A 1usqA-4cmhB:
undetectable		 1usqA-4cmhB:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_B_CLMB1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4cmh HEAVY CHAIN OF
SAR650984-FAB
FRAGMENT
(Mus
musculus) 		4 / 6 GLY B  54
PRO B  53
ILE B  51
GLY B  56
 None
 0.80A 1usqB-4cmhB:
undetectable		 1usqB-4cmhB:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4cmh HEAVY CHAIN OF
SAR650984-FAB
FRAGMENT
(Mus
musculus) 		4 / 6 GLY B  54
PRO B  53
ILE B  51
GLY B  56
 None
 0.80A 1usqC-4cmhB:
undetectable		 1usqC-4cmhB:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4cmh HEAVY CHAIN OF
SAR650984-FAB
FRAGMENT
(Mus
musculus) 		4 / 6 GLY B  54
PRO B  53
ILE B  51
GLY B  56
 None
 0.81A 1usqD-4cmhB:
undetectable		 1usqD-4cmhB:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4cmh HEAVY CHAIN OF
SAR650984-FAB
FRAGMENT
(Mus
musculus) 		4 / 6 GLY B  54
PRO B  53
ILE B  51
GLY B  56
 None
 0.80A 1usqE-4cmhB:
undetectable		 1usqE-4cmhB:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_F_CLMF1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4cmh HEAVY CHAIN OF
SAR650984-FAB
FRAGMENT
(Mus
musculus) 		5 / 7 GLY B  54
PRO B  53
THR B  58
ILE B  51
GLY B  56
 None
 1.08A 1usqF-4cmhB:
2.2		 1usqF-4cmhB:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		 4cmh HEAVY CHAIN OF
SAR650984-FAB
FRAGMENT
(Mus
musculus) 		5 / 12 LYS B  63
LEU B  86
LEU B  83
LEU B  20
ALA B  92
 None
 0.97A 2bxqA-4cmhB:
undetectable		 2bxqA-4cmhB:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_A_CLMA1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4cmh HEAVY CHAIN OF
SAR650984-FAB
FRAGMENT
(Mus
musculus) 		4 / 6 GLY B  54
PRO B  53
ILE B  51
GLY B  56
 None
 0.87A 2jkjA-4cmhB:
undetectable		 2jkjA-4cmhB:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_E_CLME1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4cmh HEAVY CHAIN OF
SAR650984-FAB
FRAGMENT
(Mus
musculus) 		5 / 7 GLY B  54
PRO B  53
THR B  58
ILE B  51
GLY B  56
 None
 1.11A 2jkjE-4cmhB:
undetectable		 2jkjE-4cmhB:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_A_CLMA1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4cmh HEAVY CHAIN OF
SAR650984-FAB
FRAGMENT
(Mus
musculus) 		5 / 7 GLY B  54
PRO B  53
THR B  58
ILE B  51
GLY B  56
 None
 1.11A 2jklA-4cmhB:
undetectable		 2jklA-4cmhB:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_B_CLMB1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4cmh HEAVY CHAIN OF
SAR650984-FAB
FRAGMENT
(Mus
musculus) 		4 / 6 GLY B  54
PRO B  53
ILE B  51
GLY B  56
 None
 0.86A 2jklB-4cmhB:
undetectable		 2jklB-4cmhB:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4cmh HEAVY CHAIN OF
SAR650984-FAB
FRAGMENT
(Mus
musculus) 		5 / 7 GLY B  54
PRO B  53
THR B  58
ILE B  51
GLY B  56
 None
 1.11A 2jklC-4cmhB:
undetectable		 2jklC-4cmhB:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_D_CLMD1145_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4cmh HEAVY CHAIN OF
SAR650984-FAB
FRAGMENT
(Mus
musculus) 		5 / 7 GLY B  54
PRO B  53
THR B  58
ILE B  51
GLY B  56
 None
 1.10A 2jklD-4cmhB:
undetectable		 2jklD-4cmhB:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4cmh HEAVY CHAIN OF
SAR650984-FAB
FRAGMENT
(Mus
musculus) 		5 / 7 GLY B  54
PRO B  53
THR B  58
ILE B  51
GLY B  56
 None
 1.11A 2jklE-4cmhB:
undetectable		 2jklE-4cmhB:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4cmh HEAVY CHAIN OF
SAR650984-FAB
FRAGMENT
(Mus
musculus) 		5 / 7 GLY B  54
PRO B  53
THR B  58
ILE B  51
GLY B  56
 None
 1.11A 2jklF-4cmhB:
undetectable		 2jklF-4cmhB:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA302_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 4cmh HEAVY CHAIN OF
SAR650984-FAB
FRAGMENT
(Mus
musculus) 		4 / 6 LEU B 196
GLY B 197
ALA B 132
PRO B 133
 None
 0.52A 3huoA-4cmhB:
undetectable		 3huoA-4cmhB:
23.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M7K_H_ACTH302_0
(10H10 HEAVY CHAIN)		 4cmh HEAVY CHAIN OF
SAR650984-FAB
FRAGMENT
(Mus
musculus) 		4 / 5 VAL B   2
TYR B  27
ARG B  98
TYR B 109
 None
 0.18A 4m7kH-4cmhB:
26.1		 4m7kH-4cmhB:
82.48