SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4cn8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_E_FUAE706_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4cn8 PROXIMAL THREAD
MATRIX PROTEIN 1
(Mytilus
galloprovinciali
s) 		5 / 10 THR A 195
PHE A  87
LEU A  83
VAL A  80
VAL A 236
 EDO  A1448 (-3.9A)
None
None
None
None
 1.45A 1q23E-4cn8A:
undetectable		 1q23E-4cn8A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_H_FUAH709_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4cn8 PROXIMAL THREAD
MATRIX PROTEIN 1
(Mytilus
galloprovinciali
s) 		5 / 12 LEU A 189
VAL A 148
PHE A 153
VAL A 194
VAL A 102
 None
 1.23A 1q23H-4cn8A:
undetectable
1q23I-4cn8A:
undetectable		 1q23H-4cn8A:
19.55
1q23I-4cn8A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_K_FUAK712_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4cn8 PROXIMAL THREAD
MATRIX PROTEIN 1
(Mytilus
galloprovinciali
s) 		5 / 10 THR A 195
PHE A  87
LEU A  83
VAL A  80
VAL A 236
 EDO  A1448 (-3.9A)
None
None
None
None
 1.47A 1q23K-4cn8A:
undetectable		 1q23K-4cn8A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDU_A_CIAA1003_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 4cn8 PROXIMAL THREAD
MATRIX PROTEIN 1
(Mytilus
galloprovinciali
s) 		5 / 11 ILE A 407
VAL A 416
ALA A 394
LEU A 435
ILE A 392
 None
 1.21A 1uduA-4cn8A:
undetectable		 1uduA-4cn8A:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4cn8 PROXIMAL THREAD
MATRIX PROTEIN 1
(Mytilus
galloprovinciali
s) 		4 / 8 LYS A 234
LEU A 233
PHE A  79
LEU A  83
 None
 0.87A 1v54C-4cn8A:
undetectable
1v54J-4cn8A:
undetectable		 1v54C-4cn8A:
20.00
1v54J-4cn8A:
7.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4cn8 PROXIMAL THREAD
MATRIX PROTEIN 1
(Mytilus
galloprovinciali
s) 		4 / 8 LYS A 234
LEU A 233
PHE A  79
LEU A  83
 None
 0.91A 1v54P-4cn8A:
undetectable
1v54W-4cn8A:
undetectable		 1v54P-4cn8A:
20.00
1v54W-4cn8A:
7.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC5_A_NCAA2001_0
(NAD-DEPENDENT
DEACETYLASE)		 4cn8 PROXIMAL THREAD
MATRIX PROTEIN 1
(Mytilus
galloprovinciali
s) 		4 / 7 SER A  62
ILE A  65
ILE A 201
ASP A 173
 None
 0.97A 1yc5A-4cn8A:
5.2		 1yc5A-4cn8A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4cn8 PROXIMAL THREAD
MATRIX PROTEIN 1
(Mytilus
galloprovinciali
s) 		4 / 8 LYS A 234
LEU A 233
PHE A  79
LEU A  83
 None
 0.86A 2dyrC-4cn8A:
undetectable
2dyrJ-4cn8A:
undetectable		 2dyrC-4cn8A:
20.00
2dyrJ-4cn8A:
7.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4cn8 PROXIMAL THREAD
MATRIX PROTEIN 1
(Mytilus
galloprovinciali
s) 		4 / 8 LYS A 234
LEU A 233
PHE A  79
LEU A  83
 None
 0.91A 2dyrP-4cn8A:
undetectable
2dyrW-4cn8A:
undetectable		 2dyrP-4cn8A:
20.00
2dyrW-4cn8A:
7.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4cn8 PROXIMAL THREAD
MATRIX PROTEIN 1
(Mytilus
galloprovinciali
s) 		4 / 8 LYS A 234
LEU A 233
PHE A  79
LEU A  83
 None
 0.92A 2eikP-4cn8A:
undetectable
2eikW-4cn8A:
undetectable		 2eikP-4cn8A:
20.00
2eikW-4cn8A:
7.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4cn8 PROXIMAL THREAD
MATRIX PROTEIN 1
(Mytilus
galloprovinciali
s) 		4 / 8 LYS A 234
LEU A 233
PHE A  79
LEU A  83
 None
 0.87A 2eilC-4cn8A:
undetectable
2eilJ-4cn8A:
undetectable		 2eilC-4cn8A:
20.00
2eilJ-4cn8A:
7.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4cn8 PROXIMAL THREAD
MATRIX PROTEIN 1
(Mytilus
galloprovinciali
s) 		4 / 7 LYS A 234
LEU A 233
PHE A  79
LEU A  83
 None
 0.87A 2eimP-4cn8A:
undetectable
2eimW-4cn8A:
undetectable		 2eimP-4cn8A:
20.00
2eimW-4cn8A:
7.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 4cn8 PROXIMAL THREAD
MATRIX PROTEIN 1
(Mytilus
galloprovinciali
s) 		5 / 12 MET A  76
PHE A 226
ILE A 213
LEU A 145
SER A  62
 None
 1.22A 2ogyB-4cn8A:
undetectable		 2ogyB-4cn8A:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA601_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 4cn8 PROXIMAL THREAD
MATRIX PROTEIN 1
(Mytilus
galloprovinciali
s) 		4 / 7 GLY A 338
ALA A 344
VAL A 364
ILE A 409
 None
 0.75A 3a2qA-4cn8A:
undetectable		 3a2qA-4cn8A:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 4cn8 PROXIMAL THREAD
MATRIX PROTEIN 1
(Mytilus
galloprovinciali
s) 		4 / 7 LYS A 234
LEU A 233
PHE A  79
LEU A  83
 None
 0.98A 3asnP-4cn8A:
undetectable
3asnW-4cn8A:
undetectable		 3asnP-4cn8A:
20.00
3asnW-4cn8A:
7.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 4cn8 PROXIMAL THREAD
MATRIX PROTEIN 1
(Mytilus
galloprovinciali
s) 		4 / 7 LYS A 234
LEU A 233
PHE A  79
LEU A  83
 None
 0.96A 3asoP-4cn8A:
undetectable
3asoW-4cn8A:
undetectable		 3asoP-4cn8A:
20.00
3asoW-4cn8A:
7.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_P_CLMP221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4cn8 PROXIMAL THREAD
MATRIX PROTEIN 1
(Mytilus
galloprovinciali
s) 		5 / 9 THR A 139
PHE A 105
SER A 176
LEU A 210
VAL A 220
 None
 1.46A 3u9fP-4cn8A:
undetectable		 3u9fP-4cn8A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 4cn8 PROXIMAL THREAD
MATRIX PROTEIN 1
(Mytilus
galloprovinciali
s) 		5 / 9 ASP A 130
GLY A 127
PHE A 113
VAL A  57
GLY A 101
 None
 1.37A 4acaB-4cn8A:
5.3
4acaC-4cn8A:
5.6		 4acaB-4cn8A:
23.33
4acaC-4cn8A:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 4cn8 PROXIMAL THREAD
MATRIX PROTEIN 1
(Mytilus
galloprovinciali
s) 		5 / 9 ILE A 128
GLY A 127
PHE A 113
VAL A  57
GLY A 101
 None
 1.32A 4acaB-4cn8A:
5.3
4acaC-4cn8A:
5.6		 4acaB-4cn8A:
23.33
4acaC-4cn8A:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_A_ADNA401_1
(APH(2'')-ID)		 4cn8 PROXIMAL THREAD
MATRIX PROTEIN 1
(Mytilus
galloprovinciali
s) 		5 / 11 GLY A 204
PRO A 182
ILE A 213
LEU A 170
ILE A 141
 None
 0.94A 4dt8A-4cn8A:
undetectable		 4dt8A-4cn8A:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_B_ADNB401_1
(APH(2'')-ID)		 4cn8 PROXIMAL THREAD
MATRIX PROTEIN 1
(Mytilus
galloprovinciali
s) 		5 / 10 GLY A 204
PRO A 182
ILE A 213
LEU A 170
ILE A 141
 None
 0.82A 4dt8B-4cn8A:
undetectable		 4dt8B-4cn8A:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTA_B_ADNB401_1
(APH(2'')-ID)		 4cn8 PROXIMAL THREAD
MATRIX PROTEIN 1
(Mytilus
galloprovinciali
s) 		4 / 8 PRO A 182
ILE A 213
LEU A 170
ILE A 141
 None
 0.83A 4dtaB-4cn8A:
undetectable		 4dtaB-4cn8A:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 4cn8 PROXIMAL THREAD
MATRIX PROTEIN 1
(Mytilus
galloprovinciali
s) 		4 / 5 ASN A 265
PRO A 329
ASP A 339
ASP A 369
 None
EDO  A1449 ( 4.3A)
None
None
 1.12A 4n48B-4cn8A:
undetectable		 4n48B-4cn8A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSN_A_MMZA503_1
(FLAVIN-CONTAINING
MONOOXYGENASE)		 4cn8 PROXIMAL THREAD
MATRIX PROTEIN 1
(Mytilus
galloprovinciali
s) 		3 / 3 ASN A 218
SER A 411
SER A 412
 None
 0.62A 5gsnA-4cn8A:
3.0		 5gsnA-4cn8A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA301_1
(CHITOSANASE)		 4cn8 PROXIMAL THREAD
MATRIX PROTEIN 1
(Mytilus
galloprovinciali
s) 		4 / 8 ILE A 264
ASP A 369
GLY A 333
THR A 335
 None
 1.03A 5hwaA-4cn8A:
undetectable		 5hwaA-4cn8A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OS7_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 4cn8 PROXIMAL THREAD
MATRIX PROTEIN 1
(Mytilus
galloprovinciali
s) 		3 / 3 HIS A 380
SER A 383
LYS A 387
 None
 1.48A 5os7A-4cn8A:
undetectable		 5os7A-4cn8A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_B_OQRB302_0
(SULFOTRANSFERASE)		 4cn8 PROXIMAL THREAD
MATRIX PROTEIN 1
(Mytilus
galloprovinciali
s) 		5 / 10 ILE A  55
VAL A 236
PHE A  87
SER A  86
GLU A  47
 None
 1.36A 5tixB-4cn8A:
2.4		 5tixB-4cn8A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 4cn8 PROXIMAL THREAD
MATRIX PROTEIN 1
(Mytilus
galloprovinciali
s) 		4 / 6 LYS A 234
LEU A 233
PHE A  79
LEU A  83
 None
 0.91A 5x19P-4cn8A:
undetectable		 5x19P-4cn8A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4cn8 PROXIMAL THREAD
MATRIX PROTEIN 1
(Mytilus
galloprovinciali
s) 		4 / 7 LYS A 234
LEU A 233
PHE A  79
LEU A  83
 None
 0.89A 5x1fP-4cn8A:
undetectable
5x1fW-4cn8A:
undetectable		 5x1fP-4cn8A:
20.00
5x1fW-4cn8A:
7.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_2
(CARBONIC ANHYDRASE 2)		 4cn8 PROXIMAL THREAD
MATRIX PROTEIN 1
(Mytilus
galloprovinciali
s) 		4 / 5 HIS A 184
GLU A 192
LEU A  58
VAL A 168
 None
 1.19A 6bc9A-4cn8A:
undetectable		 6bc9A-4cn8A:
10.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GMD_B_ACTB402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 4cn8 PROXIMAL THREAD
MATRIX PROTEIN 1
(Mytilus
galloprovinciali
s) 		3 / 3 HIS A 380
SER A 383
LYS A 387
 None
 1.48A 6gmdB-4cn8A:
undetectable		 6gmdB-4cn8A:
21.80