SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4cnm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4cnm TROPHOBLAST
GLYCOPROTEIN
(Homo
sapiens) 		4 / 7 LYS A 172
LEU A 175
LEU A 147
PHE A 138
 None
 1.08A 1v55C-4cnmA:
undetectable
1v55J-4cnmA:
undetectable		 1v55C-4cnmA:
21.14
1v55J-4cnmA:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AB2_A_SNLA502_2
(MINERALOCORTICOID
RECEPTOR)		 4cnm TROPHOBLAST
GLYCOPROTEIN
(Homo
sapiens) 		4 / 6 LEU A 233
LEU A 212
LEU A 239
LEU A 257
 None
 0.94A 2ab2A-4cnmA:
undetectable		 2ab2A-4cnmA:
25.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4cnm TROPHOBLAST
GLYCOPROTEIN
(Homo
sapiens) 		4 / 7 LYS A 172
LEU A 175
LEU A 147
PHE A 138
 None
 1.03A 2dysC-4cnmA:
undetectable
2dysJ-4cnmA:
undetectable		 2dysC-4cnmA:
21.14
2dysJ-4cnmA:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4cnm TROPHOBLAST
GLYCOPROTEIN
(Homo
sapiens) 		4 / 7 LYS A 172
LEU A 175
LEU A 147
PHE A 138
 None
 1.05A 2eijC-4cnmA:
undetectable
2eijJ-4cnmA:
undetectable		 2eijC-4cnmA:
21.14
2eijJ-4cnmA:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4cnm TROPHOBLAST
GLYCOPROTEIN
(Homo
sapiens) 		4 / 7 LYS A 172
LEU A 175
LEU A 147
PHE A 138
 None
 1.05A 2eimC-4cnmA:
undetectable
2eimJ-4cnmA:
undetectable		 2eimC-4cnmA:
21.14
2eimJ-4cnmA:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_C_ACTC1120_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 4cnm TROPHOBLAST
GLYCOPROTEIN
(Homo
sapiens) 		3 / 3 LYS A 271
TYR A 325
PRO A 295
 None
 1.18A 2j9cC-4cnmA:
undetectable		 2j9cC-4cnmA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_G_SAMG302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 4cnm TROPHOBLAST
GLYCOPROTEIN
(Homo
sapiens) 		5 / 12 LEU A 241
SER A 253
ASP A 228
LEU A 239
LEU A 215
 None
 1.18A 3cjtG-4cnmA:
undetectable		 3cjtG-4cnmA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_A_NCAA192_0
(NICOTINAMIDASE)		 4cnm TROPHOBLAST
GLYCOPROTEIN
(Homo
sapiens) 		5 / 11 ASP A 148
LEU A 178
LEU A 149
ILE A 183
SER A 150
 CIT  A1356 ( 2.5A)
None
None
None
CIT  A1356 (-3.2A)
 1.23A 3o94A-4cnmA:
undetectable		 3o94A-4cnmA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_B_NCAB192_0
(NICOTINAMIDASE)		 4cnm TROPHOBLAST
GLYCOPROTEIN
(Homo
sapiens) 		5 / 11 ASP A 148
LEU A 178
LEU A 149
ILE A 183
SER A 150
 CIT  A1356 ( 2.5A)
None
None
None
CIT  A1356 (-3.2A)
 1.28A 3o94B-4cnmA:
undetectable		 3o94B-4cnmA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_C_NCAC192_0
(NICOTINAMIDASE)		 4cnm TROPHOBLAST
GLYCOPROTEIN
(Homo
sapiens) 		5 / 11 ASP A 148
LEU A 178
LEU A 149
ILE A 183
SER A 150
 CIT  A1356 ( 2.5A)
None
None
None
CIT  A1356 (-3.2A)
 1.26A 3o94C-4cnmA:
undetectable		 3o94C-4cnmA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_D_NCAD192_0
(NICOTINAMIDASE)		 4cnm TROPHOBLAST
GLYCOPROTEIN
(Homo
sapiens) 		5 / 11 ASP A 148
LEU A 178
LEU A 149
ILE A 183
SER A 150
 CIT  A1356 ( 2.5A)
None
None
None
CIT  A1356 (-3.2A)
 1.25A 3o94D-4cnmA:
undetectable		 3o94D-4cnmA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_J_KANJ301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4cnm TROPHOBLAST
GLYCOPROTEIN
(Homo
sapiens) 		4 / 6 ASP A 240
ASP A 292
ASN A 268
ASP A 267
 None
 1.29A 4gkhJ-4cnmA:
undetectable		 4gkhJ-4cnmA:
26.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O4D_A_ACTA406_0
(INOSITOL
HEXAKISPHOSPHATE
KINASE)		 4cnm TROPHOBLAST
GLYCOPROTEIN
(Homo
sapiens) 		4 / 7 ASP A 240
ARG A 214
SER A 262
HIS A 264
 None
 1.11A 4o4dA-4cnmA:
undetectable		 4o4dA-4cnmA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4cnm TROPHOBLAST
GLYCOPROTEIN
(Homo
sapiens) 		4 / 6 LYS A 172
LEU A 175
LEU A 147
PHE A 138
 None
 1.13A 5w97C-4cnmA:
undetectable
5w97J-4cnmA:
undetectable		 5w97C-4cnmA:
21.14
5w97J-4cnmA:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA501_1
(CYTOCHROME P450 2C9)		 4cnm TROPHOBLAST
GLYCOPROTEIN
(Homo
sapiens) 		5 / 12 VAL A 133
GLY A 136
ALA A 161
LEU A 178
LEU A 149
 None
 0.95A 5xxiA-4cnmA:
undetectable		 5xxiA-4cnmA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F5U_A_CQNA610_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 4cnm TROPHOBLAST
GLYCOPROTEIN
(Homo
sapiens) 		5 / 10 ALA A 137
LEU A 144
LEU A 175
LEU A 125
LEU A 123
 None
 0.92A 6f5uA-4cnmA:
undetectable
6f5uB-4cnmA:
undetectable		 6f5uA-4cnmA:
13.71
6f5uB-4cnmA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_F_AM2F301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 4cnm TROPHOBLAST
GLYCOPROTEIN
(Homo
sapiens) 		4 / 7 HIS A 151
GLU A 216
ASP A 240
GLU A 266
 PEG  A1351 ( 4.2A)
CIT  A1356 (-3.8A)
None
None
 1.12A 6mn4F-4cnmA:
undetectable		 6mn4F-4cnmA:
24.60