SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4coy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_D_LEUD1893_0
(AMINOACYL-TRNA
SYNTHETASE)		 4coy EPITHELIAL ADHESIN 6
([Candida]
glabrata) 		4 / 8 ASP A  69
SER A  67
TYR A  68
TYR A  88
 ACT  A1273 (-3.3A)
ACT  A1273 (-2.6A)
None
None
 1.15A 2bteD-4coyA:
undetectable		 2bteD-4coyA:
13.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6K_A_ADNA699_1
(CHLORINASE)		 4coy EPITHELIAL ADHESIN 6
([Candida]
glabrata) 		4 / 7 PHE A 111
TYR A 132
PRO A 127
THR A 125
 None
 1.49A 2q6kA-4coyA:
undetectable		 2q6kA-4coyA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBL_A_CAMA517_0
(CYTOCHROME P450-CAM)		 4coy EPITHELIAL ADHESIN 6
([Candida]
glabrata) 		4 / 7 TYR A 113
LEU A 122
THR A 120
ASP A 229
 None
 0.90A 2qblA-4coyA:
undetectable		 2qblA-4coyA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0G_A_LEUA1887_0
(AMINOACYL-TRNA
SYNTHETASE)		 4coy EPITHELIAL ADHESIN 6
([Candida]
glabrata) 		4 / 8 ASP A  69
SER A  67
TYR A  68
TYR A  88
 ACT  A1273 (-3.3A)
ACT  A1273 (-2.6A)
None
None
 1.06A 2v0gA-4coyA:
undetectable		 2v0gA-4coyA:
13.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU9_A_478A401_1
(PROTEASE)		 4coy EPITHELIAL ADHESIN 6
([Candida]
glabrata) 		4 / 8 ALA A 163
ASP A 165
ILE A 109
VAL A 169
 None
GAL  A1271 ( 2.4A)
None
None
 0.73A 3nu9A-4coyA:
undetectable		 3nu9A-4coyA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4coy EPITHELIAL ADHESIN 6
([Candida]
glabrata) 		4 / 7 PHE A 111
MET A 138
THR A 137
LEU A 136
 None
 0.80A 5b3sN-4coyA:
undetectable
5b3sW-4coyA:
undetectable		 5b3sN-4coyA:
19.30
5b3sW-4coyA:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4coy EPITHELIAL ADHESIN 6
([Candida]
glabrata) 		4 / 7 PHE A 111
MET A 138
THR A 137
LEU A 136
 None
 0.78A 5iy5N-4coyA:
undetectable
5iy5W-4coyA:
undetectable		 5iy5N-4coyA:
19.30
5iy5W-4coyA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MFX_A_ACTA701_0
(GENOME POLYPROTEIN)		 4coy EPITHELIAL ADHESIN 6
([Candida]
glabrata) 		4 / 5 THR A 154
HIS A 157
ALA A 213
ASP A 212
 None
 1.33A 5mfxA-4coyA:
undetectable		 5mfxA-4coyA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB5_A_NMYA301_0
(AAC(3)-IIIB PROTEIN)		 4coy EPITHELIAL ADHESIN 6
([Candida]
glabrata) 		5 / 11 TYR A 130
ASP A 124
THR A 125
GLY A 230
ASP A 229
 None
None
None
CA  A1270 ( 4.7A)
None
 1.45A 6mb5A-4coyA:
undetectable		 6mb5A-4coyA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_A_NMYA303_0
(AAC(3)-IIIB PROTEIN)		 4coy EPITHELIAL ADHESIN 6
([Candida]
glabrata) 		5 / 10 TYR A 130
ASP A 124
THR A 125
GLY A 230
ASP A 229
 None
None
None
CA  A1270 ( 4.7A)
None
 1.48A 6mb9A-4coyA:
undetectable		 6mb9A-4coyA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_B_NMYB302_0
(AAC(3)-IIIB PROTEIN)		 4coy EPITHELIAL ADHESIN 6
([Candida]
glabrata) 		5 / 10 TYR A 130
ASP A 124
THR A 125
GLY A 230
ASP A 229
 None
None
None
CA  A1270 ( 4.7A)
None
 1.48A 6mb9B-4coyA:
undetectable		 6mb9B-4coyA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_C_NMYC302_0
(AAC(3)-IIIB PROTEIN)		 4coy EPITHELIAL ADHESIN 6
([Candida]
glabrata) 		5 / 10 TYR A 130
ASP A 124
THR A 125
GLY A 230
ASP A 229
 None
None
None
CA  A1270 ( 4.7A)
None
 1.49A 6mb9C-4coyA:
undetectable		 6mb9C-4coyA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_E_LLLE301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 4coy EPITHELIAL ADHESIN 6
([Candida]
glabrata) 		4 / 7 ASP A 257
ARG A 182
TYR A 148
GLU A  64
 None
 1.26A 6mn5E-4coyA:
undetectable		 6mn5E-4coyA:
15.57