SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4cp8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_1
(PROTEIN (ADENOSINE
KINASE))		 4cp8 ALLOPHANATE
HYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 12 LEU A  83
GLY A 131
GLY A  89
ALA A 127
LEU A 122
 None
 1.01A 1bx4A-4cp8A:
undetectable		 1bx4A-4cp8A:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H9Z_A_RWFA3001_1
(SERUM ALBUMIN)		 4cp8 ALLOPHANATE
HYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 11 ALA A 125
LEU A  83
LEU A 122
LEU A 182
ALA A 238
 None
 1.12A 1h9zA-4cp8A:
undetectable		 1h9zA-4cp8A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA443_1
(ALPHA AMYLASE)		 4cp8 ALLOPHANATE
HYDROLASE
(Pseudomonas
sp.
ADP) 		4 / 8 SER A 424
THR A 205
LEU A 221
GLU A 327
 None
 1.10A 1mxgA-4cp8A:
undetectable		 1mxgA-4cp8A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6001_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 4cp8 ALLOPHANATE
HYDROLASE
(Pseudomonas
sp.
ADP) 		3 / 3 SER A 189
GLY A 188
ARG A 328
 MLI  A1466 (-2.3A)
MLI  A1466 (-4.0A)
MLI  A1466 (-3.3A)
 0.61A 1t9wA-4cp8A:
undetectable		 1t9wA-4cp8A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WU8_C_ADNC502_1
(HYPOTHETICAL PROTEIN
PH0463)		 4cp8 ALLOPHANATE
HYDROLASE
(Pseudomonas
sp.
ADP) 		4 / 7 PHE A 196
ASN A 197
ASN A 157
VAL A 397
 None
 1.10A 1wu8A-4cp8A:
undetectable
1wu8C-4cp8A:
undetectable		 1wu8A-4cp8A:
19.88
1wu8C-4cp8A:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_A_CTXA11_1
(CES1 PROTEIN)		 4cp8 ALLOPHANATE
HYDROLASE
(Pseudomonas
sp.
ADP) 		4 / 8 MET A 386
LEU A 456
GLY A 457
LEU A 297
 None
 0.86A 1ya4A-4cp8A:
undetectable		 1ya4A-4cp8A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1435_1
(CHITINASE)		 4cp8 ALLOPHANATE
HYDROLASE
(Pseudomonas
sp.
ADP) 		4 / 6 TYR A 320
GLY A 190
SER A 166
ARG A 191
 MLI  A1466 (-4.5A)
None
None
None
 1.38A 2a3cA-4cp8A:
undetectable		 2a3cA-4cp8A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AKE_A_TRPA479_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4cp8 ALLOPHANATE
HYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 12 THR A 390
GLY A 440
GLY A 431
ILE A 192
PHE A 196
 None
 1.36A 2akeA-4cp8A:
undetectable		 2akeA-4cp8A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_A_TRPA601_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4cp8 ALLOPHANATE
HYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 12 THR A 390
GLY A 440
GLY A 431
ILE A 192
PHE A 196
 None
 1.34A 2azxA-4cp8A:
undetectable		 2azxA-4cp8A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_B_TRPB603_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4cp8 ALLOPHANATE
HYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 12 THR A 390
GLY A 440
GLY A 431
ILE A 192
PHE A 196
 None
 1.34A 2azxB-4cp8A:
undetectable		 2azxB-4cp8A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_B_PXLB1005_1
(PYRIDOXINE KINASE)		 4cp8 ALLOPHANATE
HYDROLASE
(Pseudomonas
sp.
ADP) 		4 / 7 LEU A 388
THR A 390
GLY A 190
ASP A 185
 None
None
None
MLI  A1466 ( 4.9A)
 0.86A 2ddwB-4cp8A:
undetectable		 2ddwB-4cp8A:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEN_B_017B402_1
(PROTEASE)		 4cp8 ALLOPHANATE
HYDROLASE
(Pseudomonas
sp.
ADP) 		6 / 12 GLY A  98
ALA A  97
ASP A  95
GLY A 131
ILE A 130
VAL A 123
 None
 1.33A 2ienA-4cp8A:
undetectable		 2ienA-4cp8A:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEO_A_017A402_1
(PROTEASE)		 4cp8 ALLOPHANATE
HYDROLASE
(Pseudomonas
sp.
ADP) 		6 / 12 GLY A  98
ALA A  97
ASP A  95
GLY A 131
ILE A 130
VAL A 123
 None
 1.27A 2ieoA-4cp8A:
undetectable		 2ieoA-4cp8A:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_B_SC2B1294_1
(FICOLIN-2)		 4cp8 ALLOPHANATE
HYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 9 VAL A 178
GLY A  89
SER A 181
LEU A 227
SER A 169
 None
 1.32A 2j2pB-4cp8A:
undetectable
2j2pC-4cp8A:
undetectable		 2j2pB-4cp8A:
17.42
2j2pC-4cp8A:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OD9_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 4cp8 ALLOPHANATE
HYDROLASE
(Pseudomonas
sp.
ADP) 		3 / 3 PHE A 307
PHE A 312
PHE A 417
 None
 0.85A 2od9A-4cp8A:
undetectable		 2od9A-4cp8A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQG_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 4cp8 ALLOPHANATE
HYDROLASE
(Pseudomonas
sp.
ADP) 		3 / 3 PHE A 307
PHE A 312
PHE A 417
 None
 0.85A 2qqgA-4cp8A:
undetectable		 2qqgA-4cp8A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		 4cp8 ALLOPHANATE
HYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 12 GLY A 183
SER A 181
ALA A 228
ALA A 234
ASP A 233
 None
 1.10A 3keeA-4cp8A:
undetectable		 3keeA-4cp8A:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		 4cp8 ALLOPHANATE
HYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 12 GLY A 183
SER A 181
ALA A 228
ALA A 234
ASP A 233
 None
 1.07A 3keeC-4cp8A:
undetectable		 3keeC-4cp8A:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		 4cp8 ALLOPHANATE
HYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 12 GLY A 183
SER A 181
ALA A 228
ALA A 234
ASP A 233
 None
 1.03A 3keeD-4cp8A:
undetectable		 3keeD-4cp8A:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP201_1
(PROTEIN S100-A4)		 4cp8 ALLOPHANATE
HYDROLASE
(Pseudomonas
sp.
ADP) 		4 / 7 PHE A 196
GLY A 164
GLY A 412
PHE A 156
 None
 0.96A 3ko0M-4cp8A:
undetectable
3ko0P-4cp8A:
undetectable		 3ko0M-4cp8A:
9.92
3ko0P-4cp8A:
9.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_C_CELC682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4cp8 ALLOPHANATE
HYDROLASE
(Pseudomonas
sp.
ADP) 		4 / 7 SER A 167
LEU A 437
ILE A 192
PHE A 196
 None
 0.99A 3ln1C-4cp8A:
undetectable		 3ln1C-4cp8A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_A_RITA600_1
(CYTOCHROME P450 3A4)		 4cp8 ALLOPHANATE
HYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 12 SER A 165
LEU A 214
ALA A 103
ILE A  56
GLY A  89
 MLI  A1466 ( 3.7A)
None
None
None
None
 1.07A 3nxuA-4cp8A:
undetectable		 3nxuA-4cp8A:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4cp8 ALLOPHANATE
HYDROLASE
(Pseudomonas
sp.
ADP) 		4 / 6 ILE A 332
LEU A 335
ARG A 146
THR A 147
 None
 1.18A 3wg7A-4cp8A:
undetectable
3wg7J-4cp8A:
undetectable		 3wg7A-4cp8A:
22.67
3wg7J-4cp8A:
8.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_A_CHDA506_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4cp8 ALLOPHANATE
HYDROLASE
(Pseudomonas
sp.
ADP) 		4 / 4 PRO A 273
LEU A 388
ILE A 444
ARG A 191
 None
 1.36A 4f4dA-4cp8A:
undetectable		 4f4dA-4cp8A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKI_A_IMNA201_1
(TRANSTHYRETIN)		 4cp8 ALLOPHANATE
HYDROLASE
(Pseudomonas
sp.
ADP) 		3 / 3 LYS A 355
LEU A 352
ALA A 354
 None
 0.69A 4ikiA-4cp8A:
undetectable		 4ikiA-4cp8A:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_2
(NUPC FAMILY PROTEIN)		 4cp8 ALLOPHANATE
HYDROLASE
(Pseudomonas
sp.
ADP) 		3 / 3 THR A 184
ASN A 197
PHE A 196
 None
 0.84A 4pd9A-4cp8A:
undetectable		 4pd9A-4cp8A:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QDJ_A_SAMA301_0
(MAGNESIUM-PROTOPORPH
YRIN
O-METHYLTRANSFERASE)		 4cp8 ALLOPHANATE
HYDROLASE
(Pseudomonas
sp.
ADP) 		6 / 12 VAL A 123
GLY A  89
SER A 169
ILE A 128
LEU A  59
VAL A  96
 None
 1.17A 4qdjA-4cp8A:
undetectable		 4qdjA-4cp8A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QDJ_A_SAMA301_0
(MAGNESIUM-PROTOPORPH
YRIN
O-METHYLTRANSFERASE)		 4cp8 ALLOPHANATE
HYDROLASE
(Pseudomonas
sp.
ADP) 		6 / 12 VAL A 123
GLY A 131
GLY A  89
SER A 169
LEU A  59
VAL A  96
 None
 1.28A 4qdjA-4cp8A:
undetectable		 4qdjA-4cp8A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 4cp8 ALLOPHANATE
HYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 12 THR A 390
GLY A 190
GLY A 188
SER A 225
ALA A 238
 None
None
MLI  A1466 (-4.0A)
None
None
 0.86A 4uciA-4cp8A:
undetectable		 4uciA-4cp8A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 4cp8 ALLOPHANATE
HYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 12 THR A 390
GLY A 190
GLY A 188
SER A 225
ALA A 238
 None
None
MLI  A1466 (-4.0A)
None
None
 0.87A 4uciB-4cp8A:
undetectable		 4uciB-4cp8A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 4cp8 ALLOPHANATE
HYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 12 THR A 390
GLY A 190
GLY A 188
SER A 225
ALA A 238
 None
None
MLI  A1466 (-4.0A)
None
None
 0.91A 4uckA-4cp8A:
undetectable		 4uckA-4cp8A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 4cp8 ALLOPHANATE
HYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 12 THR A 390
GLY A 190
GLY A 188
SER A 225
ALA A 238
 None
None
MLI  A1466 (-4.0A)
None
None
 0.91A 4uckB-4cp8A:
undetectable		 4uckB-4cp8A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDY_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4cp8 ALLOPHANATE
HYDROLASE
(Pseudomonas
sp.
ADP) 		3 / 3 ALA A  27
TYR A  29
PRO A 179
 None
 0.70A 4zdyA-4cp8A:
undetectable		 4zdyA-4cp8A:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJ8_A_SUVA2001_2
(HUMAN OX1R FUSION
PROTEIN TO P.ABYSII
GLYCOGEN SYNTHASE)		 4cp8 ALLOPHANATE
HYDROLASE
(Pseudomonas
sp.
ADP) 		4 / 6 ILE A 192
PRO A 193
ILE A 151
VAL A 397
 None
 0.85A 4zj8A-4cp8A:
undetectable		 4zj8A-4cp8A:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H2U_A_1N1A501_2
(PROTEIN-TYROSINE
KINASE 6)		 4cp8 ALLOPHANATE
HYDROLASE
(Pseudomonas
sp.
ADP) 		3 / 3 ILE A 305
MET A 300
ASP A 384
 None
 0.72A 5h2uA-4cp8A:
undetectable		 5h2uA-4cp8A:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NM5_B_LOCB502_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 4cp8 ALLOPHANATE
HYDROLASE
(Pseudomonas
sp.
ADP) 		4 / 4 ASN A 197
SER A 166
ALA A 170
VAL A 173
 None
 1.36A 5nm5A-4cp8A:
undetectable		 5nm5A-4cp8A:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TL8_A_X2NA502_1
(PROTEIN CYP51)		 4cp8 ALLOPHANATE
HYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 12 ALA A 218
ALA A 174
ALA A 172
THR A 133
THR A 140
 None
None
None
None
MLI  A1466 ( 4.9A)
 1.22A 5tl8A-4cp8A:
undetectable		 5tl8A-4cp8A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA504_1
(CYTOCHROME P450 2C9)		 4cp8 ALLOPHANATE
HYDROLASE
(Pseudomonas
sp.
ADP) 		4 / 8 ILE A 444
PHE A 417
THR A 379
PHE A 307
 None
 1.05A 5x23A-4cp8A:
undetectable		 5x23A-4cp8A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4cp8 ALLOPHANATE
HYDROLASE
(Pseudomonas
sp.
ADP) 		4 / 8 HIS A  18
ASP A  34
THR A  33
LEU A  68
 None
 1.20A 5z84A-4cp8A:
undetectable
5z84C-4cp8A:
undetectable
5z84P-4cp8A:
undetectable		 5z84A-4cp8A:
22.67
5z84C-4cp8A:
19.38
5z84P-4cp8A:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4cp8 ALLOPHANATE
HYDROLASE
(Pseudomonas
sp.
ADP) 		4 / 7 LEU A  68
HIS A  18
ASP A  34
THR A  33
 None
 1.23A 5z84C-4cp8A:
undetectable
5z84N-4cp8A:
0.5
5z84P-4cp8A:
undetectable		 5z84C-4cp8A:
19.38
5z84N-4cp8A:
22.67
5z84P-4cp8A:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4cp8 ALLOPHANATE
HYDROLASE
(Pseudomonas
sp.
ADP) 		4 / 7 LEU A  68
HIS A  18
ASP A  34
THR A  33
 None
 1.22A 5z85C-4cp8A:
undetectable
5z85N-4cp8A:
undetectable
5z85P-4cp8A:
undetectable		 5z85C-4cp8A:
19.38
5z85N-4cp8A:
22.67
5z85P-4cp8A:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4cp8 ALLOPHANATE
HYDROLASE
(Pseudomonas
sp.
ADP) 		4 / 8 HIS A  18
ASP A  34
THR A  33
LEU A  68
 None
 1.19A 5z86A-4cp8A:
undetectable
5z86C-4cp8A:
undetectable
5z86P-4cp8A:
undetectable		 5z86A-4cp8A:
22.67
5z86C-4cp8A:
19.38
5z86P-4cp8A:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4cp8 ALLOPHANATE
HYDROLASE
(Pseudomonas
sp.
ADP) 		4 / 8 HIS A  18
ASP A  34
THR A  33
LEU A  68
 None
 1.20A 5zcpA-4cp8A:
undetectable
5zcpC-4cp8A:
undetectable
5zcpP-4cp8A:
undetectable		 5zcpA-4cp8A:
22.67
5zcpC-4cp8A:
19.38
5zcpP-4cp8A:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4cp8 ALLOPHANATE
HYDROLASE
(Pseudomonas
sp.
ADP) 		4 / 8 LEU A  68
HIS A  18
ASP A  34
THR A  33
 None
 1.21A 5zcpC-4cp8A:
undetectable
5zcpN-4cp8A:
undetectable
5zcpP-4cp8A:
undetectable		 5zcpC-4cp8A:
19.38
5zcpN-4cp8A:
22.67
5zcpP-4cp8A:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MDQ_A_TESA604_0
(SERUM ALBUMIN)		 4cp8 ALLOPHANATE
HYDROLASE
(Pseudomonas
sp.
ADP) 		4 / 8 ALA A 254
GLY A 207
LEU A 208
ALA A 242
 None
 0.82A 6mdqA-4cp8A:
undetectable		 6mdqA-4cp8A:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MXT_A_K5YA1401_0
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		 4cp8 ALLOPHANATE
HYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 12 VAL A 240
VAL A 237
PHE A  88
HIS A 115
ILE A  94
 None
 1.40A 6mxtA-4cp8A:
undetectable		 6mxtA-4cp8A:
23.54