SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4cpn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4G_A_ZMRA466_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		12 / 12 ARG A 115
GLU A 116
ASP A 148
ARG A 222
GLU A 225
ALA A 244
GLU A 274
GLU A 275
ARG A 291
ASN A 293
ARG A 373
TYR A 408
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.3A)
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 ( 3.9A)
ZMR  A 700 (-3.0A)
ZMR  A 700 (-4.6A)
 0.29A 1a4gA-4cpnA:
75.0		 1a4gA-4cpnA:
94.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4G_A_ZMRA466_2
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		4 / 4 ARG A 149
ARG A 153
TRP A 176
ILE A 220
 ZMR  A 700 (-4.0A)
ZMR  A 700 (-4.2A)
None
None
 0.12A 1a4gA-4cpnA:
75.0		 1a4gA-4cpnA:
94.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4G_B_ZMRB466_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		12 / 12 ARG A 115
GLU A 116
ARG A 153
ARG A 222
GLU A 225
ALA A 244
GLU A 274
GLU A 275
ARG A 291
ASN A 293
ARG A 373
TYR A 408
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-4.2A)
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 ( 3.9A)
ZMR  A 700 (-3.0A)
ZMR  A 700 (-4.6A)
 0.32A 1a4gB-4cpnA:
75.2		 1a4gB-4cpnA:
94.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4G_B_ZMRB466_2
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		3 / 3 ASP A 148
ARG A 149
ILE A 220
 ZMR  A 700 (-3.3A)
ZMR  A 700 (-4.0A)
None
 0.24A 1a4gB-4cpnA:
75.2		 1a4gB-4cpnA:
94.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1F9G_A_ASCA950_0
(HYALURONATE LYASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		4 / 7 ARG A 149
ASN A 293
ARG A 373
ARG A 115
 ZMR  A 700 (-4.0A)
ZMR  A 700 ( 3.9A)
ZMR  A 700 (-3.0A)
ZMR  A 700 (-2.9A)
 1.44A 1f9gA-4cpnA:
undetectable		 1f9gA-4cpnA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J96_A_TESA903_1
(3ALPHA-HYDROXYSTEROI
D DEHYDROGENASE TYPE
3)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		4 / 6 TYR A 216
VAL A 270
ILE A 313
LEU A 253
 None
 1.22A 1j96A-4cpnA:
undetectable		 1j96A-4cpnA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7F_A_BCZA801_0
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		12 / 12 GLU A 116
LEU A 131
ASP A 148
ARG A 153
TRP A 176
ILE A 220
ARG A 222
GLU A 225
GLU A 274
GLU A 275
ARG A 291
TYR A 408
 ZMR  A 700 (-3.5A)
None
ZMR  A 700 (-3.3A)
ZMR  A 700 (-4.2A)
None
None
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 (-4.6A)
 0.48A 1l7fA-4cpnA:
54.2		 1l7fA-4cpnA:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7F_A_BCZA801_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		3 / 3 ARG A 115
ARG A 149
ARG A 373
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-4.0A)
ZMR  A 700 (-3.0A)
 0.28A 1l7fA-4cpnA:
54.2		 1l7fA-4cpnA:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7G_A_BCZA801_0
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		5 / 12 ASP A 148
ARG A 149
ILE A 220
ARG A 222
GLU A 225
 ZMR  A 700 (-3.3A)
ZMR  A 700 (-4.0A)
None
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
 1.28A 1l7gA-4cpnA:
54.1		 1l7gA-4cpnA:
28.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7G_A_BCZA801_0
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		12 / 12 LEU A 131
ASP A 148
ARG A 149
ARG A 153
TRP A 176
ILE A 220
ARG A 222
GLU A 225
GLU A 274
GLU A 275
ARG A 291
TYR A 408
 None
ZMR  A 700 (-3.3A)
ZMR  A 700 (-4.0A)
ZMR  A 700 (-4.2A)
None
None
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 (-4.6A)
 0.47A 1l7gA-4cpnA:
54.1		 1l7gA-4cpnA:
28.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7H_A_BCZA801_0
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		11 / 12 GLU A 116
LEU A 131
ASP A 148
ARG A 153
TRP A 176
ILE A 220
ARG A 222
GLU A 225
GLU A 274
GLU A 275
TYR A 408
 ZMR  A 700 (-3.5A)
None
ZMR  A 700 (-3.3A)
ZMR  A 700 (-4.2A)
None
None
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-4.6A)
 0.49A 1l7hA-4cpnA:
54.1		 1l7hA-4cpnA:
28.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7H_A_BCZA801_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		3 / 3 ARG A 115
ARG A 149
ARG A 373
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-4.0A)
ZMR  A 700 (-3.0A)
 0.26A 1l7hA-4cpnA:
54.1		 1l7hA-4cpnA:
28.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NNC_A_ZMRA479_1
(NEURAMINIDASE N9)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		12 / 12 ARG A 115
GLU A 116
ARG A 149
ARG A 222
GLU A 225
ALA A 244
GLU A 274
GLU A 275
ARG A 291
ASN A 293
ARG A 373
TYR A 408
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-4.0A)
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 ( 3.9A)
ZMR  A 700 (-3.0A)
ZMR  A 700 (-4.6A)
 0.60A 1nncA-4cpnA:
54.0		 1nncA-4cpnA:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NNC_A_ZMRA479_1
(NEURAMINIDASE N9)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		6 / 12 ARG A 222
ALA A 244
GLU A 274
GLU A 275
ARG A 115
TYR A 408
 ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.9A)
ZMR  A 700 (-4.6A)
 1.47A 1nncA-4cpnA:
54.0		 1nncA-4cpnA:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NNC_A_ZMRA479_2
(NEURAMINIDASE N9)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		4 / 4 ASP A 148
ARG A 153
TRP A 176
ILE A 220
 ZMR  A 700 (-3.3A)
ZMR  A 700 (-4.2A)
None
None
 0.15A 1nncA-4cpnA:
54.0		 1nncA-4cpnA:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CDQ_B_SAMB1500_0
(ASPARTOKINASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		4 / 7 ASP A 193
TRP A 176
LEU A 131
GLU A 116
 None
None
None
ZMR  A 700 (-3.5A)
 1.05A 2cdqB-4cpnA:
undetectable		 2cdqB-4cpnA:
21.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_A_ZMRA1477_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		12 / 12 ARG A 115
GLU A 116
ASP A 148
ARG A 222
GLU A 225
ALA A 244
GLU A 274
GLU A 275
ARG A 291
ASN A 293
ARG A 373
TYR A 408
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.3A)
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 ( 3.9A)
ZMR  A 700 (-3.0A)
ZMR  A 700 (-4.6A)
 0.44A 2cmlA-4cpnA:
54.0		 2cmlA-4cpnA:
30.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_A_ZMRA1477_2
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		5 / 5 LEU A 131
ARG A 149
ARG A 153
TRP A 176
ILE A 220
 None
ZMR  A 700 (-4.0A)
ZMR  A 700 (-4.2A)
None
None
 0.16A 2cmlA-4cpnA:
54.0		 2cmlA-4cpnA:
30.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_B_ZMRB2477_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		12 / 12 ARG A 115
GLU A 116
ASP A 148
ARG A 222
GLU A 225
ALA A 244
GLU A 274
GLU A 275
ARG A 291
ASN A 293
ARG A 373
TYR A 408
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.3A)
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 ( 3.9A)
ZMR  A 700 (-3.0A)
ZMR  A 700 (-4.6A)
 0.47A 2cmlB-4cpnA:
54.0		 2cmlB-4cpnA:
30.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_B_ZMRB2477_2
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		5 / 5 LEU A 131
ARG A 149
ARG A 153
TRP A 176
ILE A 220
 None
ZMR  A 700 (-4.0A)
ZMR  A 700 (-4.2A)
None
None
 0.19A 2cmlB-4cpnA:
54.0		 2cmlB-4cpnA:
30.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_C_ZMRC3477_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		12 / 12 ARG A 115
GLU A 116
ASP A 148
ARG A 222
GLU A 225
ALA A 244
GLU A 274
GLU A 275
ARG A 291
ASN A 293
ARG A 373
TYR A 408
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.3A)
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 ( 3.9A)
ZMR  A 700 (-3.0A)
ZMR  A 700 (-4.6A)
 0.47A 2cmlC-4cpnA:
54.1		 2cmlC-4cpnA:
30.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_C_ZMRC3477_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		5 / 12 GLU A 225
ALA A 244
ARG A 291
ASN A 293
TYR A 408
 ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.8A)
ZMR  A 700 ( 3.9A)
ZMR  A 700 (-4.6A)
 1.06A 2cmlC-4cpnA:
54.1		 2cmlC-4cpnA:
30.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_C_ZMRC3477_2
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		5 / 5 LEU A 131
ARG A 149
ARG A 153
TRP A 176
ILE A 220
 None
ZMR  A 700 (-4.0A)
ZMR  A 700 (-4.2A)
None
None
 0.26A 2cmlC-4cpnA:
54.1		 2cmlC-4cpnA:
30.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_D_ZMRD4477_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		12 / 12 ARG A 115
GLU A 116
ASP A 148
ARG A 222
GLU A 225
ALA A 244
GLU A 274
GLU A 275
ARG A 291
ASN A 293
ARG A 373
TYR A 408
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.3A)
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 ( 3.9A)
ZMR  A 700 (-3.0A)
ZMR  A 700 (-4.6A)
 0.46A 2cmlD-4cpnA:
53.9		 2cmlD-4cpnA:
30.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_D_ZMRD4477_2
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		5 / 5 LEU A 131
ARG A 149
ARG A 153
TRP A 176
ILE A 220
 None
ZMR  A 700 (-4.0A)
ZMR  A 700 (-4.2A)
None
None
 0.21A 2cmlD-4cpnA:
53.9		 2cmlD-4cpnA:
30.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F0Z_A_ZMRA381_1
(SIALIDASE 2)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		5 / 12 ARG A 115
GLU A 275
ARG A 291
ARG A 373
TYR A 408
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 (-3.0A)
ZMR  A 700 (-4.6A)
 0.44A 2f0zA-4cpnA:
25.6		 2f0zA-4cpnA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F0Z_A_ZMRA381_1
(SIALIDASE 2)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		5 / 12 ARG A 153
GLU A 275
ARG A 291
ARG A 373
TYR A 408
 ZMR  A 700 (-4.2A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 (-3.0A)
ZMR  A 700 (-4.6A)
 1.07A 2f0zA-4cpnA:
25.6		 2f0zA-4cpnA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F10_A_BCZA382_0
(SIALIDASE 2)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		5 / 12 ARG A 115
GLU A 275
ARG A 291
ARG A 373
TYR A 408
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 (-3.0A)
ZMR  A 700 (-4.6A)
 0.42A 2f10A-4cpnA:
25.7		 2f10A-4cpnA:
23.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HTQ_A_ZMRA472_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		5 / 12 ALA A 244
GLU A 274
GLU A 275
ARG A 115
TYR A 408
 ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.9A)
ZMR  A 700 (-4.6A)
 1.33A 2htqA-4cpnA:
52.7		 2htqA-4cpnA:
31.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HTQ_A_ZMRA472_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		11 / 12 ARG A 115
GLU A 116
ARG A 149
ARG A 153
GLU A 225
ALA A 244
GLU A 274
GLU A 275
ARG A 291
ARG A 373
TYR A 408
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-4.0A)
ZMR  A 700 (-4.2A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 (-3.0A)
ZMR  A 700 (-4.6A)
 0.60A 2htqA-4cpnA:
52.7		 2htqA-4cpnA:
31.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HTQ_A_ZMRA472_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		5 / 12 ARG A 291
GLU A 275
GLU A 225
ALA A 440
GLU A 116
 ZMR  A 700 (-2.8A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-3.5A)
None
ZMR  A 700 (-3.5A)
 1.48A 2htqA-4cpnA:
52.7		 2htqA-4cpnA:
31.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HTQ_A_ZMRA472_2
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		4 / 4 ASP A 148
TRP A 176
ILE A 220
ARG A 222
 ZMR  A 700 (-3.3A)
None
None
ZMR  A 700 (-3.8A)
 0.43A 2htqA-4cpnA:
52.7		 2htqA-4cpnA:
31.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HTU_A_BCZA801_0
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		11 / 12 GLU A 116
LEU A 131
ARG A 149
ARG A 153
TRP A 176
SER A 177
ILE A 220
ARG A 222
GLU A 274
ARG A 291
TYR A 408
 ZMR  A 700 (-3.5A)
None
ZMR  A 700 (-4.0A)
ZMR  A 700 (-4.2A)
None
ZMR  A 700 ( 4.6A)
None
ZMR  A 700 (-3.8A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-2.8A)
ZMR  A 700 (-4.6A)
 0.49A 2htuA-4cpnA:
53.3		 2htuA-4cpnA:
31.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HTU_A_BCZA801_0
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		5 / 12 GLU A 225
ARG A 149
ILE A 220
ARG A 291
TYR A 408
 ZMR  A 700 (-3.5A)
ZMR  A 700 (-4.0A)
None
ZMR  A 700 (-2.8A)
ZMR  A 700 (-4.6A)
 1.42A 2htuA-4cpnA:
53.3		 2htuA-4cpnA:
31.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HTU_A_BCZA801_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		4 / 4 ARG A 115
ASP A 148
GLU A 225
ARG A 373
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.3A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.0A)
 0.22A 2htuA-4cpnA:
53.2		 2htuA-4cpnA:
31.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3B7E_A_ZMRA1001_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		11 / 12 ARG A 115
GLU A 116
ASP A 148
ARG A 222
GLU A 225
GLU A 274
GLU A 275
ARG A 291
ASN A 293
ARG A 373
TYR A 408
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.3A)
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 ( 3.9A)
ZMR  A 700 (-3.0A)
ZMR  A 700 (-4.6A)
 0.37A 3b7eA-4cpnA:
53.7		 3b7eA-4cpnA:
32.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3B7E_A_ZMRA1001_2
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		4 / 4 ARG A 149
ARG A 153
TRP A 176
ILE A 220
 ZMR  A 700 (-4.0A)
ZMR  A 700 (-4.2A)
None
None
 0.12A 3b7eA-4cpnA:
53.7		 3b7eA-4cpnA:
32.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3B7E_B_ZMRB1002_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		11 / 12 ARG A 115
GLU A 116
ASP A 148
ARG A 222
GLU A 225
GLU A 274
GLU A 275
ARG A 291
ASN A 293
ARG A 373
TYR A 408
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.3A)
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 ( 3.9A)
ZMR  A 700 (-3.0A)
ZMR  A 700 (-4.6A)
 0.38A 3b7eB-4cpnA:
53.7		 3b7eB-4cpnA:
32.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3B7E_B_ZMRB1002_2
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		4 / 4 ARG A 149
ARG A 153
TRP A 176
ILE A 220
 ZMR  A 700 (-4.0A)
ZMR  A 700 (-4.2A)
None
None
 0.13A 3b7eB-4cpnA:
53.7		 3b7eB-4cpnA:
32.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1009_1
(SERUM ALBUMIN)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		4 / 8 GLU A 225
SER A 177
HIS A 133
ARG A 115
 ZMR  A 700 (-3.5A)
ZMR  A 700 ( 4.6A)
None
ZMR  A 700 (-2.9A)
 1.18A 3b9lA-4cpnA:
undetectable		 3b9lA-4cpnA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1200_1
(SERUM ALBUMIN)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		4 / 5 ILE A 113
HIS A 133
ARG A 146
GLY A 144
 None
 1.09A 3b9mA-4cpnA:
undetectable		 3b9mA-4cpnA:
20.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CKZ_A_ZMRA469_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		10 / 12 ARG A 115
GLU A 116
ARG A 149
GLU A 225
GLU A 274
GLU A 275
ARG A 291
ASN A 293
ARG A 373
TYR A 408
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-4.0A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 ( 3.9A)
ZMR  A 700 (-3.0A)
ZMR  A 700 (-4.6A)
 0.39A 3ckzA-4cpnA:
53.7		 3ckzA-4cpnA:
32.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CKZ_A_ZMRA469_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		6 / 12 GLU A 225
ARG A 149
GLU A 274
ARG A 291
ASN A 293
TYR A 408
 ZMR  A 700 (-3.5A)
ZMR  A 700 (-4.0A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-2.8A)
ZMR  A 700 ( 3.9A)
ZMR  A 700 (-4.6A)
 1.39A 3ckzA-4cpnA:
53.7		 3ckzA-4cpnA:
32.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CKZ_A_ZMRA469_2
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		5 / 6 ASP A 148
ARG A 153
TRP A 176
ILE A 220
ARG A 222
 ZMR  A 700 (-3.3A)
ZMR  A 700 (-4.2A)
None
None
ZMR  A 700 (-3.8A)
 0.72A 3ckzA-4cpnA:
53.7		 3ckzA-4cpnA:
32.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CKZ_A_ZMRA469_2
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		4 / 6 TRP A 176
ILE A 220
ARG A 222
SER A 243
 None
None
ZMR  A 700 (-3.8A)
None
 1.17A 3ckzA-4cpnA:
53.7		 3ckzA-4cpnA:
32.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DLC_A_SAMA220_0
(PUTATIVE
S-ADENOSYL-L-METHION
INE-DEPENDENT
METHYLTRANSFERASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		5 / 12 GLY A 406
GLY A 375
ASP A 431
VAL A 429
HIS A 438
 None
 1.34A 3dlcA-4cpnA:
undetectable		 3dlcA-4cpnA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		5 / 12 ILE A  97
MET A 399
THR A 457
LEU A 447
ILE A 424
 None
 1.23A 3em0B-4cpnA:
undetectable		 3em0B-4cpnA:
16.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K37_A_BCZA468_0
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		12 / 12 ARG A 115
GLU A 116
LEU A 131
ARG A 153
TRP A 176
ARG A 222
GLU A 225
ALA A 244
GLU A 274
GLU A 275
ARG A 291
TYR A 408
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
None
ZMR  A 700 (-4.2A)
None
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 (-4.6A)
 0.43A 3k37A-4cpnA:
75.0		 3k37A-4cpnA:
97.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K37_A_BCZA468_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		3 / 3 ASP A 148
ARG A 149
ARG A 373
 ZMR  A 700 (-3.3A)
ZMR  A 700 (-4.0A)
ZMR  A 700 (-3.0A)
 0.19A 3k37A-4cpnA:
75.0		 3k37A-4cpnA:
97.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K37_B_BCZB468_0
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		12 / 12 ARG A 115
GLU A 116
LEU A 131
ASP A 148
ARG A 153
TRP A 176
ARG A 222
GLU A 225
ALA A 244
GLU A 275
ARG A 291
ARG A 373
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
None
ZMR  A 700 (-3.3A)
ZMR  A 700 (-4.2A)
None
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 (-3.0A)
 0.30A 3k37B-4cpnA:
74.9		 3k37B-4cpnA:
97.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K37_B_BCZB468_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		3 / 3 ARG A 149
GLU A 274
TYR A 408
 ZMR  A 700 (-4.0A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-4.6A)
 0.48A 3k37B-4cpnA:
74.9		 3k37B-4cpnA:
97.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_A_BCZA1001_0
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		12 / 12 ARG A 115
GLU A 116
LEU A 131
ARG A 149
ARG A 153
ARG A 222
GLU A 225
ALA A 244
GLU A 274
GLU A 275
ARG A 291
TYR A 408
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
None
ZMR  A 700 (-4.0A)
ZMR  A 700 (-4.2A)
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 (-4.6A)
 0.54A 3k39A-4cpnA:
73.8		 3k39A-4cpnA:
96.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_A_BCZA1001_0
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		5 / 12 ARG A 291
GLU A 275
GLU A 225
ALA A 440
GLU A 116
 ZMR  A 700 (-2.8A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-3.5A)
None
ZMR  A 700 (-3.5A)
 1.47A 3k39A-4cpnA:
73.8		 3k39A-4cpnA:
96.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_B_BCZB1001_0
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		12 / 12 ARG A 115
GLU A 116
LEU A 131
ASP A 148
ARG A 149
ARG A 153
ARG A 222
GLU A 225
ALA A 244
GLU A 275
ARG A 291
TYR A 408
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
None
ZMR  A 700 (-3.3A)
ZMR  A 700 (-4.0A)
ZMR  A 700 (-4.2A)
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 (-4.6A)
 0.47A 3k39B-4cpnA:
73.9		 3k39B-4cpnA:
96.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_B_BCZB1001_0
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		5 / 12 ARG A 291
GLU A 275
GLU A 225
ALA A 440
GLU A 116
 ZMR  A 700 (-2.8A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-3.5A)
None
ZMR  A 700 (-3.5A)
 1.46A 3k39B-4cpnA:
73.9		 3k39B-4cpnA:
96.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_C_BCZC1001_0
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		12 / 12 ARG A 115
GLU A 116
LEU A 131
ASP A 148
ARG A 149
ARG A 153
ARG A 222
GLU A 225
ALA A 244
GLU A 274
GLU A 275
ARG A 291
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
None
ZMR  A 700 (-3.3A)
ZMR  A 700 (-4.0A)
ZMR  A 700 (-4.2A)
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
 0.52A 3k39C-4cpnA:
74.0		 3k39C-4cpnA:
96.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_C_BCZC1001_0
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		5 / 12 ARG A 291
GLU A 275
GLU A 225
ALA A 440
GLU A 116
 ZMR  A 700 (-2.8A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-3.5A)
None
ZMR  A 700 (-3.5A)
 1.46A 3k39C-4cpnA:
74.0		 3k39C-4cpnA:
96.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_D_BCZD1001_0
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		5 / 12 ARG A 222
ALA A 244
GLU A 274
GLU A 275
ARG A 115
 ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.9A)
 1.23A 3k39D-4cpnA:
73.9		 3k39D-4cpnA:
96.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_D_BCZD1001_0
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		12 / 12 GLU A 116
LEU A 131
ASP A 148
ARG A 149
ARG A 153
ARG A 222
GLU A 225
ALA A 244
GLU A 274
GLU A 275
ARG A 291
ARG A 373
 ZMR  A 700 (-3.5A)
None
ZMR  A 700 (-3.3A)
ZMR  A 700 (-4.0A)
ZMR  A 700 (-4.2A)
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 (-3.0A)
 0.54A 3k39D-4cpnA:
73.9		 3k39D-4cpnA:
96.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_E_BCZE1001_0
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		12 / 12 ARG A 115
GLU A 116
LEU A 131
ARG A 149
ARG A 153
ARG A 222
GLU A 225
ALA A 244
GLU A 274
GLU A 275
ARG A 291
TYR A 408
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
None
ZMR  A 700 (-4.0A)
ZMR  A 700 (-4.2A)
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 (-4.6A)
 0.54A 3k39E-4cpnA:
73.9		 3k39E-4cpnA:
96.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_E_BCZE1001_0
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		5 / 12 ARG A 291
GLU A 275
GLU A 225
ALA A 440
GLU A 116
 ZMR  A 700 (-2.8A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-3.5A)
None
ZMR  A 700 (-3.5A)
 1.45A 3k39E-4cpnA:
73.9		 3k39E-4cpnA:
96.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_F_BCZF1001_0
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		12 / 12 ARG A 115
GLU A 116
LEU A 131
ARG A 149
ARG A 153
ARG A 222
GLU A 225
ALA A 244
GLU A 274
GLU A 275
ARG A 291
TYR A 408
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
None
ZMR  A 700 (-4.0A)
ZMR  A 700 (-4.2A)
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 (-4.6A)
 0.53A 3k39F-4cpnA:
73.9		 3k39F-4cpnA:
96.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_G_BCZG1001_0
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		12 / 12 ARG A 115
GLU A 116
LEU A 131
ARG A 149
ARG A 153
ARG A 222
GLU A 225
ALA A 244
GLU A 274
GLU A 275
ARG A 291
TYR A 408
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
None
ZMR  A 700 (-4.0A)
ZMR  A 700 (-4.2A)
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 (-4.6A)
 0.53A 3k39G-4cpnA:
73.9		 3k39G-4cpnA:
96.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_G_BCZG1001_0
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		5 / 12 ARG A 291
GLU A 275
GLU A 225
ALA A 440
GLU A 116
 ZMR  A 700 (-2.8A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-3.5A)
None
ZMR  A 700 (-3.5A)
 1.47A 3k39G-4cpnA:
73.9		 3k39G-4cpnA:
96.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_H_BCZH1001_0
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		12 / 12 ARG A 115
GLU A 116
LEU A 131
ARG A 149
ARG A 153
ARG A 222
GLU A 225
ALA A 244
GLU A 274
GLU A 275
ARG A 291
TYR A 408
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
None
ZMR  A 700 (-4.0A)
ZMR  A 700 (-4.2A)
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 (-4.6A)
 0.53A 3k39H-4cpnA:
73.9		 3k39H-4cpnA:
96.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_H_BCZH1001_0
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		5 / 12 ARG A 291
GLU A 275
GLU A 225
ALA A 440
GLU A 116
 ZMR  A 700 (-2.8A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-3.5A)
None
ZMR  A 700 (-3.5A)
 1.47A 3k39H-4cpnA:
73.9		 3k39H-4cpnA:
96.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_I_BCZI1001_0
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		12 / 12 ARG A 115
GLU A 116
LEU A 131
ASP A 148
ARG A 149
ARG A 153
ARG A 222
GLU A 225
ALA A 244
GLU A 274
GLU A 275
ARG A 291
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
None
ZMR  A 700 (-3.3A)
ZMR  A 700 (-4.0A)
ZMR  A 700 (-4.2A)
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
 0.52A 3k39I-4cpnA:
73.9		 3k39I-4cpnA:
96.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_I_BCZI1001_0
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		5 / 12 GLU A 116
LEU A 131
ASP A 148
ARG A 153
ARG A 373
 ZMR  A 700 (-3.5A)
None
ZMR  A 700 (-3.3A)
ZMR  A 700 (-4.2A)
ZMR  A 700 (-3.0A)
 1.50A 3k39I-4cpnA:
73.9		 3k39I-4cpnA:
96.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_J_BCZJ1001_0
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		12 / 12 ARG A 115
GLU A 116
LEU A 131
ASP A 148
ARG A 149
ARG A 153
ARG A 222
GLU A 225
ALA A 244
GLU A 274
GLU A 275
ARG A 291
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
None
ZMR  A 700 (-3.3A)
ZMR  A 700 (-4.0A)
ZMR  A 700 (-4.2A)
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
 0.52A 3k39J-4cpnA:
74.0		 3k39J-4cpnA:
96.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_K_BCZK1001_0
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		12 / 12 ARG A 115
GLU A 116
LEU A 131
ASP A 148
ARG A 149
ARG A 153
ARG A 222
GLU A 225
ALA A 244
GLU A 274
GLU A 275
ARG A 291
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
None
ZMR  A 700 (-3.3A)
ZMR  A 700 (-4.0A)
ZMR  A 700 (-4.2A)
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
 0.53A 3k39K-4cpnA:
73.9		 3k39K-4cpnA:
96.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_K_BCZK1001_0
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		5 / 12 ARG A 291
GLU A 275
GLU A 225
ALA A 440
GLU A 116
 ZMR  A 700 (-2.8A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-3.5A)
None
ZMR  A 700 (-3.5A)
 1.47A 3k39K-4cpnA:
73.9		 3k39K-4cpnA:
96.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_L_BCZL1001_0
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		12 / 12 ARG A 115
GLU A 116
LEU A 131
ASP A 148
ARG A 149
ARG A 153
ARG A 222
GLU A 225
ALA A 244
GLU A 274
GLU A 275
ARG A 291
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
None
ZMR  A 700 (-3.3A)
ZMR  A 700 (-4.0A)
ZMR  A 700 (-4.2A)
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
 0.52A 3k39L-4cpnA:
73.9		 3k39L-4cpnA:
96.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_L_BCZL1001_0
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		5 / 12 ARG A 291
GLU A 275
GLU A 225
ALA A 440
GLU A 116
 ZMR  A 700 (-2.8A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-3.5A)
None
ZMR  A 700 (-3.5A)
 1.47A 3k39L-4cpnA:
73.9		 3k39L-4cpnA:
96.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_M_BCZM1001_0
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		12 / 12 ARG A 115
GLU A 116
LEU A 131
ARG A 149
ARG A 153
ARG A 222
GLU A 225
ALA A 244
GLU A 274
GLU A 275
ARG A 291
TYR A 408
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
None
ZMR  A 700 (-4.0A)
ZMR  A 700 (-4.2A)
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 (-4.6A)
 0.52A 3k39M-4cpnA:
73.9		 3k39M-4cpnA:
96.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_N_BCZN1001_0
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		12 / 12 GLU A 116
LEU A 131
ARG A 149
ARG A 153
ARG A 222
GLU A 225
ALA A 244
GLU A 274
GLU A 275
ARG A 291
ARG A 373
TYR A 408
 ZMR  A 700 (-3.5A)
None
ZMR  A 700 (-4.0A)
ZMR  A 700 (-4.2A)
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 (-3.0A)
ZMR  A 700 (-4.6A)
 0.54A 3k39N-4cpnA:
73.9		 3k39N-4cpnA:
96.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_O_BCZO1001_0
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		12 / 12 ARG A 115
GLU A 116
LEU A 131
ARG A 149
ARG A 153
ARG A 222
GLU A 225
ALA A 244
GLU A 274
GLU A 275
ARG A 373
TYR A 408
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
None
ZMR  A 700 (-4.0A)
ZMR  A 700 (-4.2A)
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-3.0A)
ZMR  A 700 (-4.6A)
 0.55A 3k39O-4cpnA:
73.9		 3k39O-4cpnA:
96.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_P_BCZP1001_0
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		12 / 12 GLU A 116
LEU A 131
ARG A 149
ARG A 153
ARG A 222
GLU A 225
ALA A 244
GLU A 274
GLU A 275
ARG A 291
ARG A 373
TYR A 408
 ZMR  A 700 (-3.5A)
None
ZMR  A 700 (-4.0A)
ZMR  A 700 (-4.2A)
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 (-3.0A)
ZMR  A 700 (-4.6A)
 0.55A 3k39P-4cpnA:
73.9		 3k39P-4cpnA:
96.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG801_0
(GLUTAMATE RECEPTOR 2)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		3 / 3 PRO A 111
SER A 109
ASN A 168
 None
 0.89A 3lslG-4cpnA:
undetectable		 3lslG-4cpnA:
19.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SAN_A_ZMRA901_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		11 / 12 ARG A 115
GLU A 116
ARG A 222
GLU A 225
ALA A 244
GLU A 274
GLU A 275
ARG A 291
ASN A 293
ARG A 373
TYR A 408
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 ( 3.9A)
ZMR  A 700 (-3.0A)
ZMR  A 700 (-4.6A)
 0.40A 3sanA-4cpnA:
54.1		 3sanA-4cpnA:
32.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SAN_A_ZMRA901_2
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		5 / 5 ASP A 148
ARG A 149
ARG A 153
TRP A 176
ILE A 220
 ZMR  A 700 (-3.3A)
ZMR  A 700 (-4.0A)
ZMR  A 700 (-4.2A)
None
None
 0.15A 3sanA-4cpnA:
53.9		 3sanA-4cpnA:
32.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SAN_B_ZMRB901_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		11 / 12 ARG A 115
GLU A 116
ARG A 222
GLU A 225
ALA A 244
GLU A 274
GLU A 275
ARG A 291
ASN A 293
ARG A 373
TYR A 408
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 ( 3.9A)
ZMR  A 700 (-3.0A)
ZMR  A 700 (-4.6A)
 0.41A 3sanB-4cpnA:
54.0		 3sanB-4cpnA:
32.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SAN_B_ZMRB901_2
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		5 / 5 ASP A 148
ARG A 149
ARG A 153
TRP A 176
ILE A 220
 ZMR  A 700 (-3.3A)
ZMR  A 700 (-4.0A)
ZMR  A 700 (-4.2A)
None
None
 0.12A 3sanB-4cpnA:
54.1		 3sanB-4cpnA:
32.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_C_9PLC1_1
(CYTOCHROME P450 2A13)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		4 / 7 PHE A 351
PHE A 301
THR A 318
LEU A 393
 None
 1.05A 3t3sC-4cpnA:
undetectable		 3t3sC-4cpnA:
23.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TI5_A_ZMRA1002_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		11 / 12 ARG A 115
GLU A 116
ASP A 148
ARG A 222
GLU A 225
GLU A 274
GLU A 275
ARG A 291
ASN A 293
ARG A 373
TYR A 408
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.3A)
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 ( 3.9A)
ZMR  A 700 (-3.0A)
ZMR  A 700 (-4.6A)
 0.39A 3ti5A-4cpnA:
53.8		 3ti5A-4cpnA:
32.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TI5_A_ZMRA1002_2
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		4 / 4 ARG A 149
ARG A 153
TRP A 176
ILE A 220
 ZMR  A 700 (-4.0A)
ZMR  A 700 (-4.2A)
None
None
 0.14A 3ti5A-4cpnA:
53.8		 3ti5A-4cpnA:
32.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TI5_B_ZMRB1002_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		11 / 12 ARG A 115
GLU A 116
ASP A 148
ARG A 222
GLU A 225
GLU A 274
GLU A 275
ARG A 291
ASN A 293
ARG A 373
TYR A 408
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.3A)
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 ( 3.9A)
ZMR  A 700 (-3.0A)
ZMR  A 700 (-4.6A)
 0.41A 3ti5B-4cpnA:
53.8		 3ti5B-4cpnA:
32.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TI5_B_ZMRB1002_2
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		4 / 4 ARG A 149
ARG A 153
TRP A 176
ILE A 220
 ZMR  A 700 (-4.0A)
ZMR  A 700 (-4.2A)
None
None
 0.14A 3ti5B-4cpnA:
53.8		 3ti5B-4cpnA:
32.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TIC_A_ZMRA1002_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		5 / 12 ALA A 244
GLU A 274
GLU A 275
ARG A 115
TYR A 408
 ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.9A)
ZMR  A 700 (-4.6A)
 1.48A 3ticA-4cpnA:
55.2		 3ticA-4cpnA:
30.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TIC_A_ZMRA1002_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		12 / 12 ARG A 115
GLU A 116
ASP A 148
TRP A 176
GLU A 225
ALA A 244
GLU A 274
GLU A 275
ARG A 291
ASN A 293
ARG A 373
TYR A 408
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.3A)
None
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 ( 3.9A)
ZMR  A 700 (-3.0A)
ZMR  A 700 (-4.6A)
 0.45A 3ticA-4cpnA:
55.2		 3ticA-4cpnA:
30.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TIC_A_ZMRA1002_2
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		5 / 5 LEU A 131
ARG A 149
ARG A 153
ILE A 220
ARG A 222
 None
ZMR  A 700 (-4.0A)
ZMR  A 700 (-4.2A)
None
ZMR  A 700 (-3.8A)
 0.22A 3ticA-4cpnA:
55.2		 3ticA-4cpnA:
30.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TIC_B_ZMRB1002_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		12 / 12 ARG A 115
GLU A 116
ASP A 148
ARG A 222
GLU A 225
ALA A 244
GLU A 274
GLU A 275
ARG A 291
ASN A 293
ARG A 373
TYR A 408
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.3A)
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 ( 3.9A)
ZMR  A 700 (-3.0A)
ZMR  A 700 (-4.6A)
 0.48A 3ticB-4cpnA:
55.1		 3ticB-4cpnA:
30.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TIC_B_ZMRB1002_2
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		4 / 4 ARG A 149
ARG A 153
TRP A 176
ILE A 220
 ZMR  A 700 (-4.0A)
ZMR  A 700 (-4.2A)
None
None
 0.10A 3ticB-4cpnA:
55.1		 3ticB-4cpnA:
30.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TIC_C_ZMRC1002_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		12 / 12 ARG A 115
GLU A 116
ASP A 148
ARG A 222
GLU A 225
ALA A 244
GLU A 274
GLU A 275
ARG A 291
ASN A 293
ARG A 373
TYR A 408
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.3A)
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 ( 3.9A)
ZMR  A 700 (-3.0A)
ZMR  A 700 (-4.6A)
 0.47A 3ticC-4cpnA:
55.1		 3ticC-4cpnA:
30.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TIC_C_ZMRC1002_2
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		4 / 4 ARG A 149
ARG A 153
TRP A 176
ILE A 220
 ZMR  A 700 (-4.0A)
ZMR  A 700 (-4.2A)
None
None
 0.11A 3ticC-4cpnA:
55.1		 3ticC-4cpnA:
30.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TIC_D_ZMRD1002_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		12 / 12 ARG A 115
GLU A 116
ASP A 148
ARG A 222
GLU A 225
ALA A 244
GLU A 274
GLU A 275
ARG A 291
ASN A 293
ARG A 373
TYR A 408
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.3A)
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 ( 3.9A)
ZMR  A 700 (-3.0A)
ZMR  A 700 (-4.6A)
 0.47A 3ticD-4cpnA:
55.2		 3ticD-4cpnA:
30.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TIC_D_ZMRD1002_2
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		5 / 5 LEU A 131
ARG A 149
ARG A 153
TRP A 176
ILE A 220
 None
ZMR  A 700 (-4.0A)
ZMR  A 700 (-4.2A)
None
None
 0.11A 3ticD-4cpnA:
55.0		 3ticD-4cpnA:
30.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7N_A_ZMRA601_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		11 / 12 ARG A 115
GLU A 116
ASP A 148
ARG A 222
GLU A 225
GLU A 274
GLU A 275
ARG A 291
ASN A 293
ARG A 373
TYR A 408
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.3A)
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 ( 3.9A)
ZMR  A 700 (-3.0A)
ZMR  A 700 (-4.6A)
 0.47A 4b7nA-4cpnA:
53.4		 4b7nA-4cpnA:
34.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7N_A_ZMRA601_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		5 / 12 ARG A 222
GLU A 274
GLU A 275
ARG A 115
TYR A 408
 ZMR  A 700 (-3.8A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.9A)
ZMR  A 700 (-4.6A)
 1.48A 4b7nA-4cpnA:
53.4		 4b7nA-4cpnA:
34.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7N_A_ZMRA601_2
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		3 / 3 ARG A 149
ARG A 153
TRP A 176
 ZMR  A 700 (-4.0A)
ZMR  A 700 (-4.2A)
None
 0.13A 4b7nA-4cpnA:
53.4		 4b7nA-4cpnA:
34.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7Q_A_ZMRA601_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		11 / 12 ARG A 115
GLU A 116
ASP A 148
ARG A 222
GLU A 225
GLU A 274
GLU A 275
ARG A 291
ASN A 293
ARG A 373
TYR A 408
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.3A)
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 ( 3.9A)
ZMR  A 700 (-3.0A)
ZMR  A 700 (-4.6A)
 0.45A 4b7qA-4cpnA:
53.2		 4b7qA-4cpnA:
34.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7Q_A_ZMRA601_2
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		3 / 3 ARG A 149
ARG A 153
ILE A 220
 ZMR  A 700 (-4.0A)
ZMR  A 700 (-4.2A)
None
 0.25A 4b7qA-4cpnA:
53.2		 4b7qA-4cpnA:
34.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7Q_B_ZMRB601_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		11 / 12 ARG A 115
GLU A 116
ASP A 148
ARG A 222
GLU A 225
GLU A 274
GLU A 275
ARG A 291
ASN A 293
ARG A 373
TYR A 408
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.3A)
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 ( 3.9A)
ZMR  A 700 (-3.0A)
ZMR  A 700 (-4.6A)
 0.49A 4b7qB-4cpnA:
53.2		 4b7qB-4cpnA:
34.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7Q_B_ZMRB601_2
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		4 / 4 LEU A 131
ARG A 149
ARG A 153
TRP A 176
 None
ZMR  A 700 (-4.0A)
ZMR  A 700 (-4.2A)
None
 0.19A 4b7qB-4cpnA:
53.2		 4b7qB-4cpnA:
34.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7Q_C_ZMRC601_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		11 / 12 ARG A 115
GLU A 116
ASP A 148
ARG A 222
GLU A 225
GLU A 274
GLU A 275
ARG A 291
ASN A 293
ARG A 373
TYR A 408
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.3A)
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 ( 3.9A)
ZMR  A 700 (-3.0A)
ZMR  A 700 (-4.6A)
 0.46A 4b7qC-4cpnA:
53.3		 4b7qC-4cpnA:
34.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7Q_C_ZMRC601_2
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		3 / 3 ARG A 149
ARG A 153
ILE A 220
 ZMR  A 700 (-4.0A)
ZMR  A 700 (-4.2A)
None
 0.16A 4b7qC-4cpnA:
53.3		 4b7qC-4cpnA:
34.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7Q_D_ZMRD601_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		11 / 12 ARG A 115
GLU A 116
ASP A 148
ARG A 222
GLU A 225
GLU A 274
GLU A 275
ARG A 291
ASN A 293
ARG A 373
TYR A 408
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.3A)
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 ( 3.9A)
ZMR  A 700 (-3.0A)
ZMR  A 700 (-4.6A)
 0.49A 4b7qD-4cpnA:
53.4		 4b7qD-4cpnA:
34.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7Q_D_ZMRD601_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		5 / 12 ARG A 222
GLU A 274
GLU A 275
ARG A 115
TYR A 408
 ZMR  A 700 (-3.8A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.9A)
ZMR  A 700 (-4.6A)
 1.43A 4b7qD-4cpnA:
53.4		 4b7qD-4cpnA:
34.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7Q_D_ZMRD601_2
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		4 / 4 ARG A 149
ARG A 153
TRP A 176
ILE A 220
 ZMR  A 700 (-4.0A)
ZMR  A 700 (-4.2A)
None
None
 0.27A 4b7qD-4cpnA:
53.4		 4b7qD-4cpnA:
34.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_A_ZMRA1471_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		11 / 12 ARG A 115
GLU A 116
ARG A 222
GLU A 225
ALA A 244
GLU A 274
GLU A 275
ARG A 291
ASN A 293
ARG A 373
TYR A 408
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 ( 3.9A)
ZMR  A 700 (-3.0A)
ZMR  A 700 (-4.6A)
 0.22A 4cpzA-4cpnA:
75.5		 4cpzA-4cpnA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_A_ZMRA1471_2
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		5 / 5 LEU A 131
ASP A 148
ARG A 149
ARG A 153
TRP A 176
 None
ZMR  A 700 (-3.3A)
ZMR  A 700 (-4.0A)
ZMR  A 700 (-4.2A)
None
 0.12A 4cpzA-4cpnA:
75.5		 4cpzA-4cpnA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_B_ZMRB1471_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		11 / 12 ARG A 115
GLU A 116
ARG A 222
GLU A 225
ALA A 244
GLU A 274
GLU A 275
ARG A 291
ASN A 293
ARG A 373
TYR A 408
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 ( 3.9A)
ZMR  A 700 (-3.0A)
ZMR  A 700 (-4.6A)
 0.18A 4cpzB-4cpnA:
75.4		 4cpzB-4cpnA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_B_ZMRB1471_2
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		4 / 4 ASP A 148
ARG A 149
ARG A 153
TRP A 176
 ZMR  A 700 (-3.3A)
ZMR  A 700 (-4.0A)
ZMR  A 700 (-4.2A)
None
 0.13A 4cpzB-4cpnA:
75.4		 4cpzB-4cpnA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_C_ZMRC1470_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		12 / 12 ARG A 115
GLU A 116
ASP A 148
ARG A 222
GLU A 225
ALA A 244
GLU A 274
GLU A 275
ARG A 291
ASN A 293
ARG A 373
TYR A 408
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.3A)
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 ( 3.9A)
ZMR  A 700 (-3.0A)
ZMR  A 700 (-4.6A)
 0.20A 4cpzC-4cpnA:
75.4		 4cpzC-4cpnA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_C_ZMRC1470_2
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		3 / 3 ARG A 149
ARG A 153
TRP A 176
 ZMR  A 700 (-4.0A)
ZMR  A 700 (-4.2A)
None
 0.17A 4cpzC-4cpnA:
75.4		 4cpzC-4cpnA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_D_ZMRD1471_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		11 / 12 ARG A 115
GLU A 116
ARG A 222
GLU A 225
ALA A 244
GLU A 274
GLU A 275
ARG A 291
ASN A 293
ARG A 373
TYR A 408
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 ( 3.9A)
ZMR  A 700 (-3.0A)
ZMR  A 700 (-4.6A)
 0.24A 4cpzD-4cpnA:
75.5		 4cpzD-4cpnA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_D_ZMRD1471_2
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		4 / 4 ASP A 148
ARG A 149
ARG A 153
TRP A 176
 ZMR  A 700 (-3.3A)
ZMR  A 700 (-4.0A)
ZMR  A 700 (-4.2A)
None
 0.13A 4cpzD-4cpnA:
75.5		 4cpzD-4cpnA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_E_ZMRE1471_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		11 / 12 ARG A 115
GLU A 116
ASP A 148
ARG A 222
GLU A 225
ALA A 244
GLU A 274
GLU A 275
ARG A 291
ARG A 373
TYR A 408
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.3A)
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 (-3.0A)
ZMR  A 700 (-4.6A)
 0.24A 4cpzE-4cpnA:
75.0		 4cpzE-4cpnA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_E_ZMRE1471_2
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		3 / 3 ARG A 149
ARG A 153
TRP A 176
 ZMR  A 700 (-4.0A)
ZMR  A 700 (-4.2A)
None
 0.14A 4cpzE-4cpnA:
75.0		 4cpzE-4cpnA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_F_ZMRF1470_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		12 / 12 ARG A 115
GLU A 116
ASP A 148
ARG A 222
GLU A 225
ALA A 244
GLU A 274
GLU A 275
ARG A 291
ASN A 293
ARG A 373
TYR A 408
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.3A)
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 ( 3.9A)
ZMR  A 700 (-3.0A)
ZMR  A 700 (-4.6A)
 0.27A 4cpzF-4cpnA:
75.1		 4cpzF-4cpnA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_F_ZMRF1470_2
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		3 / 3 ARG A 149
ARG A 153
TRP A 176
 ZMR  A 700 (-4.0A)
ZMR  A 700 (-4.2A)
None
 0.12A 4cpzF-4cpnA:
75.1		 4cpzF-4cpnA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_G_ZMRG1471_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		12 / 12 ARG A 115
GLU A 116
ASP A 148
ARG A 222
GLU A 225
ALA A 244
GLU A 274
GLU A 275
ARG A 291
ASN A 293
ARG A 373
TYR A 408
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.3A)
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 ( 3.9A)
ZMR  A 700 (-3.0A)
ZMR  A 700 (-4.6A)
 0.26A 4cpzG-4cpnA:
74.8		 4cpzG-4cpnA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_G_ZMRG1471_2
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		3 / 3 ARG A 149
ARG A 153
TRP A 176
 ZMR  A 700 (-4.0A)
ZMR  A 700 (-4.2A)
None
 0.17A 4cpzG-4cpnA:
74.8		 4cpzG-4cpnA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_H_ZMRH1470_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		12 / 12 ARG A 115
GLU A 116
ASP A 148
ARG A 222
GLU A 225
ALA A 244
GLU A 274
GLU A 275
ARG A 291
ASN A 293
ARG A 373
TYR A 408
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.3A)
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 ( 3.9A)
ZMR  A 700 (-3.0A)
ZMR  A 700 (-4.6A)
 0.26A 4cpzH-4cpnA:
74.8		 4cpzH-4cpnA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_H_ZMRH1470_2
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		3 / 3 ARG A 149
ARG A 153
TRP A 176
 ZMR  A 700 (-4.0A)
ZMR  A 700 (-4.2A)
None
 0.19A 4cpzH-4cpnA:
74.8		 4cpzH-4cpnA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4I00_A_ZMRA509_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		12 / 12 ARG A 115
GLU A 116
ASP A 148
ARG A 149
ARG A 222
GLU A 225
ALA A 244
GLU A 274
GLU A 275
ARG A 291
ARG A 373
TYR A 408
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.3A)
ZMR  A 700 (-4.0A)
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 (-3.0A)
ZMR  A 700 (-4.6A)
 0.43A 4i00A-4cpnA:
53.1		 4i00A-4cpnA:
30.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4I00_A_ZMRA509_2
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		5 / 5 LEU A 131
ARG A 153
TRP A 176
ILE A 220
ASN A 293
 None
ZMR  A 700 (-4.2A)
None
None
ZMR  A 700 ( 3.9A)
 0.97A 4i00A-4cpnA:
53.0		 4i00A-4cpnA:
30.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KJL_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		5 / 12 THR A 223
ILE A 239
ARG A 251
LEU A 253
ILE A 190
 None
 1.03A 4kjlA-4cpnA:
undetectable		 4kjlA-4cpnA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_B_MRVB1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		4 / 5 TYR A 216
THR A 296
LEU A 315
THR A 267
 None
 1.40A 4mbsB-4cpnA:
undetectable		 4mbsB-4cpnA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		5 / 12 PRO A 266
MET A 238
VAL A 302
GLY A 350
THR A 273
 None
 1.38A 4mubA-4cpnA:
undetectable		 4mubA-4cpnA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWR_A_ZMRA513_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		12 / 12 ARG A 115
GLU A 116
ARG A 153
ARG A 222
GLU A 225
ALA A 244
GLU A 274
GLU A 275
ARG A 291
ASN A 293
ARG A 373
TYR A 408
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-4.2A)
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 ( 3.9A)
ZMR  A 700 (-3.0A)
ZMR  A 700 (-4.6A)
 0.50A 4mwrA-4cpnA:
54.2		 4mwrA-4cpnA:
28.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWR_A_ZMRA513_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		6 / 12 ARG A 222
ALA A 244
GLU A 274
GLU A 275
ARG A 115
TYR A 408
 ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.9A)
ZMR  A 700 (-4.6A)
 1.49A 4mwrA-4cpnA:
54.2		 4mwrA-4cpnA:
28.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWR_A_ZMRA513_2
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		5 / 5 LEU A 131
ASP A 148
ARG A 149
TRP A 176
ILE A 220
 None
ZMR  A 700 (-3.3A)
ZMR  A 700 (-4.0A)
None
None
 0.14A 4mwrA-4cpnA:
54.2		 4mwrA-4cpnA:
28.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWV_A_BCZA513_0
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		5 / 12 ASP A 148
ARG A 149
ILE A 220
ARG A 222
GLU A 225
 ZMR  A 700 (-3.3A)
ZMR  A 700 (-4.0A)
None
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
 1.26A 4mwvA-4cpnA:
54.2		 4mwvA-4cpnA:
28.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWV_A_BCZA513_0
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		12 / 12 GLU A 116
LEU A 131
ASP A 148
ARG A 149
ARG A 153
TRP A 176
ILE A 220
ARG A 222
GLU A 274
GLU A 275
ARG A 291
TYR A 408
 ZMR  A 700 (-3.5A)
None
ZMR  A 700 (-3.3A)
ZMR  A 700 (-4.0A)
ZMR  A 700 (-4.2A)
None
None
ZMR  A 700 (-3.8A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 (-4.6A)
 0.46A 4mwvA-4cpnA:
54.2		 4mwvA-4cpnA:
28.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWV_A_BCZA513_0
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		5 / 12 GLU A 225
ARG A 149
ILE A 220
ARG A 291
TYR A 408
 ZMR  A 700 (-3.5A)
ZMR  A 700 (-4.0A)
None
ZMR  A 700 (-2.8A)
ZMR  A 700 (-4.6A)
 1.47A 4mwvA-4cpnA:
54.2		 4mwvA-4cpnA:
28.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWV_A_BCZA513_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		3 / 3 ARG A 115
GLU A 225
ARG A 373
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.0A)
 0.24A 4mwvA-4cpnA:
54.2		 4mwvA-4cpnA:
28.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWX_A_ZMRA513_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		11 / 12 ARG A 115
GLU A 116
ASP A 148
ARG A 153
ARG A 222
GLU A 225
ALA A 244
GLU A 274
GLU A 275
ARG A 373
TYR A 408
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.3A)
ZMR  A 700 (-4.2A)
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-3.0A)
ZMR  A 700 (-4.6A)
 0.58A 4mwxA-4cpnA:
54.1		 4mwxA-4cpnA:
28.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWX_A_ZMRA513_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		6 / 12 ARG A 222
ALA A 244
GLU A 274
GLU A 275
ARG A 115
TYR A 408
 ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.9A)
ZMR  A 700 (-4.6A)
 1.44A 4mwxA-4cpnA:
54.1		 4mwxA-4cpnA:
28.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWX_A_ZMRA513_2
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		3 / 3 ARG A 149
TRP A 176
ILE A 220
 ZMR  A 700 (-4.0A)
None
None
 0.12A 4mwxA-4cpnA:
54.1		 4mwxA-4cpnA:
28.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MX0_A_BCZA513_0
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		12 / 12 GLU A 116
LEU A 131
ARG A 149
ARG A 153
TRP A 176
SER A 177
ARG A 222
GLU A 225
ALA A 244
GLU A 274
GLU A 275
TYR A 408
 ZMR  A 700 (-3.5A)
None
ZMR  A 700 (-4.0A)
ZMR  A 700 (-4.2A)
None
ZMR  A 700 ( 4.6A)
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-4.6A)
 0.56A 4mx0A-4cpnA:
54.2		 4mx0A-4cpnA:
28.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MX0_A_BCZA513_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		3 / 3 ARG A 115
ASP A 148
ARG A 373
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.3A)
ZMR  A 700 (-3.0A)
 0.23A 4mx0A-4cpnA:
54.2		 4mx0A-4cpnA:
28.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4WA5_A_ZMRA501_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		10 / 12 ARG A 115
GLU A 116
ASP A 148
GLU A 225
ALA A 244
GLU A 274
GLU A 275
ARG A 291
ARG A 373
TYR A 408
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.3A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 (-3.0A)
ZMR  A 700 (-4.6A)
 0.56A 4wa5A-4cpnA:
52.8		 4wa5A-4cpnA:
31.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4WA5_A_ZMRA501_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		10 / 12 ARG A 115
GLU A 116
GLU A 225
ALA A 244
GLU A 274
GLU A 275
ARG A 291
ASN A 293
ARG A 373
TYR A 408
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 ( 3.9A)
ZMR  A 700 (-3.0A)
ZMR  A 700 (-4.6A)
 0.43A 4wa5A-4cpnA:
52.8		 4wa5A-4cpnA:
31.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4WA5_A_ZMRA501_2
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		5 / 5 ARG A 149
ARG A 153
TRP A 176
ILE A 220
ARG A 222
 ZMR  A 700 (-4.0A)
ZMR  A 700 (-4.2A)
None
None
ZMR  A 700 (-3.8A)
 0.54A 4wa5A-4cpnA:
52.8		 4wa5A-4cpnA:
31.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_B_RTZB602_2
(CYTOCHROME P450 2D6)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		3 / 3 GLU A 186
ILE A 170
ALA A 180
 None
 0.61A 4wnwB-4cpnA:
undetectable		 4wnwB-4cpnA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		5 / 12 LEU A 221
VAL A 203
ILE A 260
ILE A 190
GLY A 178
 None
 0.91A 4y8wC-4cpnA:
undetectable		 4y8wC-4cpnA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDY_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		5 / 12 GLY A 144
ILE A 239
GLY A 191
LEU A 131
HIS A 133
 None
 1.13A 4zdyA-4cpnA:
undetectable		 4zdyA-4cpnA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		4 / 5 ALA A 130
ARG A 153
HIS A 100
ALA A 440
 None
ZMR  A 700 (-4.2A)
None
None
 1.08A 5a06C-4cpnA:
undetectable
5a06D-4cpnA:
undetectable		 5a06C-4cpnA:
21.05
5a06D-4cpnA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_D_ACTD403_0
(D-ALANINE--D-ALANINE
LIGASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		4 / 6 ARG A 299
GLY A 350
SER A 365
LEU A 322
 None
 1.26A 5bphD-4cpnA:
undetectable		 5bphD-4cpnA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXE_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		4 / 8 LEU A 447
GLU A 413
ARG A 355
LEU A 378
 None
 1.23A 5dxeA-4cpnA:
undetectable		 5dxeA-4cpnA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQB_B_KANB600_1
(BIFUNCTIONAL AAC/APH)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		5 / 11 SER A 177
ASP A 196
GLU A 116
GLU A 275
GLU A 225
 ZMR  A 700 ( 4.6A)
None
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-3.5A)
 1.49A 5iqbB-4cpnA:
undetectable		 5iqbB-4cpnA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQC_A_51GA600_1
(BIFUNCTIONAL AAC/APH)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		5 / 10 SER A 177
ASP A 196
GLU A 116
GLU A 275
GLU A 225
 ZMR  A 700 ( 4.6A)
None
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-3.5A)
 1.49A 5iqcA-4cpnA:
0.4		 5iqcA-4cpnA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQC_D_51GD600_1
(BIFUNCTIONAL AAC/APH)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		5 / 10 SER A 177
ASP A 196
GLU A 116
GLU A 275
GLU A 225
 ZMR  A 700 ( 4.6A)
None
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-3.5A)
 1.49A 5iqcD-4cpnA:
0.0		 5iqcD-4cpnA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQE_D_NMYD600_1
(BIFUNCTIONAL AAC/APH)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		5 / 12 SER A 177
ASP A 196
GLU A 116
GLU A 275
GLU A 225
 ZMR  A 700 ( 4.6A)
None
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-3.5A)
 1.49A 5iqeD-4cpnA:
0.0		 5iqeD-4cpnA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L17_A_ZMRA512_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		12 / 12 ARG A 115
GLU A 116
ASP A 148
ARG A 153
ARG A 222
GLU A 225
ALA A 244
GLU A 274
GLU A 275
ARG A 291
ARG A 373
TYR A 408
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.3A)
ZMR  A 700 (-4.2A)
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 (-3.0A)
ZMR  A 700 (-4.6A)
 0.51A 5l17A-4cpnA:
54.4		 5l17A-4cpnA:
28.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L17_A_ZMRA512_2
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		4 / 4 LEU A 131
ARG A 149
TRP A 176
ILE A 220
 None
ZMR  A 700 (-4.0A)
None
None
 0.17A 5l17A-4cpnA:
54.4		 5l17A-4cpnA:
28.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		5 / 12 ILE A 444
LEU A 160
PHE A 412
GLY A 411
GLY A 425
 None
 1.13A 5l6eA-4cpnA:
undetectable		 5l6eA-4cpnA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M50_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		5 / 12 ASP A 329
THR A  90
ARG A 366
GLY A 377
LEU A 378
 None
 1.23A 5m50B-4cpnA:
undetectable		 5m50B-4cpnA:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M50_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		5 / 12 ASP A 329
THR A  90
ARG A 366
GLY A 377
LEU A 378
 None
 1.21A 5m50E-4cpnA:
undetectable		 5m50E-4cpnA:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZ0_A_ZLDA301_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR ETHR)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		5 / 12 GLY A 425
ILE A 444
THR A 457
VAL A 400
LEU A 160
 None
 1.50A 5nz0A-4cpnA:
undetectable		 5nz0A-4cpnA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		3 / 3 HIS A 182
GLU A 186
TRP A 187
 None
 0.93A 5odiD-4cpnA:
undetectable		 5odiD-4cpnA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODQ_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		3 / 3 HIS A 182
GLU A 186
TRP A 187
 None
 0.78A 5odqD-4cpnA:
undetectable		 5odqD-4cpnA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODR_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		3 / 3 HIS A 182
GLU A 186
TRP A 187
 None
 0.83A 5odrD-4cpnA:
undetectable		 5odrD-4cpnA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKU_A_ZMRA901_1
(SIALIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		5 / 12 ARG A 115
GLU A 275
ARG A 291
ARG A 373
TYR A 408
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.4A)
ZMR  A 700 (-2.8A)
ZMR  A 700 (-3.0A)
ZMR  A 700 (-4.6A)
 0.37A 6ekuA-4cpnA:
14.0		 6ekuA-4cpnA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCX_A_ZMRA519_0
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		12 / 12 ARG A 115
GLU A 116
ASP A 148
ARG A 149
ARG A 153
ARG A 222
GLU A 225
ALA A 244
GLU A 274
ARG A 291
ARG A 373
TYR A 408
 ZMR  A 700 (-2.9A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.3A)
ZMR  A 700 (-4.0A)
ZMR  A 700 (-4.2A)
ZMR  A 700 (-3.8A)
ZMR  A 700 (-3.5A)
ZMR  A 700 (-3.6A)
ZMR  A 700 (-2.7A)
ZMR  A 700 (-2.8A)
ZMR  A 700 (-3.0A)
ZMR  A 700 (-4.6A)
 0.52A 6hcxA-4cpnA:
54.2		 6hcxA-4cpnA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCX_A_ZMRA519_1
(NEURAMINIDASE)		 4cpn NEURAMINIDASE
(Influenza
B
virus) 		3 / 3 TRP A 176
ILE A 220
GLU A 275
 None
None
ZMR  A 700 (-3.4A)
 0.11A 6hcxA-4cpnA:
54.2		 6hcxA-4cpnA:
20.34