SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4cq1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_A_H3PA552_1
(GLUTAMATE
DEHYDROGENASE)		 4cq1 POLYPYRIMIDINE
TRACT-BINDING
PROTEIN 2
(Homo
sapiens) 		4 / 6 ILE A 380
TYR A 362
MET A 400
ILE A 405
 None
 1.13A 3eteA-4cq1A:
undetectable
3eteE-4cq1A:
undetectable		 3eteA-4cq1A:
18.65
3eteE-4cq1A:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_F_H3PF552_1
(GLUTAMATE
DEHYDROGENASE)		 4cq1 POLYPYRIMIDINE
TRACT-BINDING
PROTEIN 2
(Homo
sapiens) 		4 / 7 MET A 400
ILE A 405
ILE A 380
TYR A 362
 None
 1.13A 3eteD-4cq1A:
undetectable
3eteF-4cq1A:
undetectable		 3eteD-4cq1A:
18.65
3eteF-4cq1A:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4cq1 POLYPYRIMIDINE
TRACT-BINDING
PROTEIN 2
(Homo
sapiens) 		4 / 7 GLY A 360
HIS A 437
ILE A 380
GLN A 353
 None
 0.86A 3fi0E-4cq1A:
undetectable		 3fi0E-4cq1A:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_C_ROFC903_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 4cq1 POLYPYRIMIDINE
TRACT-BINDING
PROTEIN 2
(Homo
sapiens) 		3 / 3 SER A 354
GLN A 353
PHE A 356
 None
 0.84A 3g4lC-4cq1A:
undetectable		 3g4lC-4cq1A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFG_B_LEUB289_0
(GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT)		 4cq1 POLYPYRIMIDINE
TRACT-BINDING
PROTEIN 2
(Homo
sapiens) 		3 / 3 PHE A 488
SER A 527
SER A 529
 None
 1.01A 3ufgB-4cq1A:
undetectable		 3ufgB-4cq1A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_B_MMSB514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4cq1 POLYPYRIMIDINE
TRACT-BINDING
PROTEIN 2
(Homo
sapiens) 		4 / 8 SER A 454
HIS A 458
LEU A 457
SER A 460
 None
 0.92A 5m8rB-4cq1A:
undetectable		 5m8rB-4cq1A:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_D_MMSD509_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4cq1 POLYPYRIMIDINE
TRACT-BINDING
PROTEIN 2
(Homo
sapiens) 		4 / 8 SER A 454
HIS A 458
LEU A 457
SER A 460
 None
 0.93A 5m8rD-4cq1A:
undetectable		 5m8rD-4cq1A:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM3_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 4cq1 POLYPYRIMIDINE
TRACT-BINDING
PROTEIN 2
(Homo
sapiens) 		4 / 6 LEU A 508
SER A 525
PHE A 526
HIS A 394
 None
 1.02A 5om3A-4cq1A:
undetectable
5om3B-4cq1A:
undetectable		 5om3A-4cq1A:
19.31
5om3B-4cq1A:
11.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_A_ERMA2001_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 4cq1 POLYPYRIMIDINE
TRACT-BINDING
PROTEIN 2
(Homo
sapiens) 		4 / 7 THR A 351
LEU A 436
VAL A 524
GLN A 448
 None
 1.06A 5tudA-4cq1A:
undetectable		 5tudA-4cq1A:
16.27