SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4cq6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGO_A_PCFA1213_0
(WNT INHIBITORY
FACTOR 1)		 4cq6 ALLENE OXIDE CYCLASE
2, CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 LEU A 146
ILE A 121
ILE A 183
PHE A 122
VAL A  21
 None
 1.00A 2ygoA-4cq6A:
undetectable		 2ygoA-4cq6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHX_B_PXLB313_1
(PYRIDOXAL KINASE)		 4cq6 ALLENE OXIDE CYCLASE
2, CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 8 VAL A  77
VAL A  73
PHE A  85
THR A 107
 None
 1.08A 3fhxB-4cq6A:
undetectable		 3fhxB-4cq6A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8J_A_ADNA401_1
(RNA 3'-TERMINAL
PHOSPHATE CYCLASE)		 4cq6 ALLENE OXIDE CYCLASE
2, CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 LEU A 134
PRO A 164
PRO A 163
ASP A 110
GLN A 132
 None
 1.29A 4o8jA-4cq6A:
0.0		 4o8jA-4cq6A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8J_B_ADNB401_1
(RNA 3'-TERMINAL
PHOSPHATE CYCLASE)		 4cq6 ALLENE OXIDE CYCLASE
2, CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 LEU A 134
PRO A 164
PRO A 163
ASP A 110
GLN A 132
 None
 1.26A 4o8jB-4cq6A:
0.2		 4o8jB-4cq6A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_B_SALB203_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 4cq6 ALLENE OXIDE CYCLASE
2, CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 6 GLY A  65
TYR A  92
LEU A 157
VAL A  21
 None
 0.94A 5x80A-4cq6A:
undetectable
5x80B-4cq6A:
undetectable		 5x80A-4cq6A:
25.13
5x80B-4cq6A:
25.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_B_8NUB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 4cq6 ALLENE OXIDE CYCLASE
2, CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 TYR A  92
SER A 111
LEU A  55
LEU A  99
VAL A 101
 None
 1.35A 6a93B-4cq6A:
undetectable		 6a93B-4cq6A:
18.66