SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4crq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA140_0
(LYSOZYME C)		 4crq ENDO-1,3-BETA-GLUCAN
ASE, FAMILY GH16
(Zobellia
galactanivorans) 		3 / 3 ASN A  54
ALA A 225
ASN A 223
 None
 0.78A 1n4fA-4crqA:
undetectable		 1n4fA-4crqA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EGV_B_SAMB1400_0
(UPF0088 PROTEIN
AQ_165)		 4crq ENDO-1,3-BETA-GLUCAN
ASE, FAMILY GH16
(Zobellia
galactanivorans) 		5 / 12 LEU A 116
ASN A 145
VAL A 226
GLY A 227
GLY A 232
 None
 0.89A 2egvB-4crqA:
undetectable		 2egvB-4crqA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_A_ACTA1467_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 4crq ENDO-1,3-BETA-GLUCAN
ASE, FAMILY GH16
(Zobellia
galactanivorans) 		4 / 5 ARG A  90
ILE A 127
GLU A  44
LYS A  92
 ACT  A1257 (-4.0A)
ACT  A1257 (-4.6A)
ACT  A1257 (-2.6A)
ACT  A1257 (-3.0A)
 1.45A 2xrzA-4crqA:
undetectable
2xrzB-4crqA:
undetectable		 2xrzA-4crqA:
15.93
2xrzB-4crqA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DA7_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4crq ENDO-1,3-BETA-GLUCAN
ASE, FAMILY GH16
(Zobellia
galactanivorans) 		5 / 10 GLY A 227
ALA A  76
VAL A 226
MET A 224
VAL A 235
 None
 1.12A 4da7A-4crqA:
undetectable		 4da7A-4crqA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G24_A_ACAA1004_1
(PENTATRICOPEPTIDE
REPEAT-CONTAINING
PROTEIN AT2G32230,
MITOCHONDRIAL)		 4crq ENDO-1,3-BETA-GLUCAN
ASE, FAMILY GH16
(Zobellia
galactanivorans) 		4 / 6 ALA A 147
LEU A 148
VAL A 172
ASP A 169
 None
 0.89A 4g24A-4crqA:
undetectable		 4g24A-4crqA:
17.13