SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4crw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_E_CVIE301_1
(REGULATORY PROTEIN
TETR)		 4crw PROBABLE
ATP-DEPENDENT RNA
HELICASE DDX6
(Homo
sapiens) 		4 / 7 GLN B 300
GLY B 412
GLN B 325
ASP B 381
 None
 1.12A 5vlmE-4crwB:
undetectable		 5vlmE-4crwB:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_S_PCFS603_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 8
CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL)		 4crw PROBABLE
ATP-DEPENDENT RNA
HELICASE DDX6
(Homo
sapiens) 		4 / 7 GLY B 372
PHE B 369
VAL B 365
SER B 349
 None
None
GOL  B1801 ( 4.3A)
None
 1.04A 6hu9S-4crwB:
undetectable
6hu9q-4crwB:
undetectable		 6hu9S-4crwB:
21.23
6hu9q-4crwB:
18.95