SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4cs5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		 4cs5 PROLIFERATING CELL
NUCLEAR ANTIGEN
(Litopenaeus
vannamei) 		5 / 10 LEU A 235
ILE A 160
GLU A 143
LEU A 139
VAL A 225
 None
 1.18A 1cqpA-4cs5A:
undetectable
1cqpB-4cs5A:
undetectable		 1cqpA-4cs5A:
22.47
1cqpB-4cs5A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FT9_A_CHDA130_0
(FATTY ACID-BINDING
PROTEIN 2, LIVER)		 4cs5 PROLIFERATING CELL
NUCLEAR ANTIGEN
(Litopenaeus
vannamei) 		5 / 12 PHE A 144
VAL A 225
VAL A  45
PHE A 215
LEU A 212
 None
 1.28A 2ft9A-4cs5A:
undetectable		 2ft9A-4cs5A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA277_0
(UNIVERSAL STRESS
PROTEIN)		 4cs5 PROLIFERATING CELL
NUCLEAR ANTIGEN
(Litopenaeus
vannamei) 		3 / 3 ASP A  41
SER A  43
ARG A 210
 None
 0.83A 3loqA-4cs5A:
undetectable		 3loqA-4cs5A:
21.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VKX_A_T3A301_1
(PROLIFERATING CELL
NUCLEAR ANTIGEN)		 4cs5 PROLIFERATING CELL
NUCLEAR ANTIGEN
(Litopenaeus
vannamei) 		4 / 6 MET A  40
LEU A  47
PRO A 129
PRO A 234
 None
 0.68A 3vkxA-4cs5A:
36.9		 3vkxA-4cs5A:
73.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD392_1
(TETX2 PROTEIN)		 4cs5 PROLIFERATING CELL
NUCLEAR ANTIGEN
(Litopenaeus
vannamei) 		4 / 5 HIS A 125
GLN A  36
SER A  49
VAL A  48
 None
 1.18A 4a99D-4cs5A:
undetectable		 4a99D-4cs5A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4cs5 PROLIFERATING CELL
NUCLEAR ANTIGEN
(Litopenaeus
vannamei) 		5 / 12 LEU A  79
LEU A  16
LEU A  72
ILE A  88
VAL A  99
 None
 1.12A 4f4dB-4cs5A:
undetectable		 4f4dB-4cs5A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_A_715A801_2
(DIPEPTIDYL PEPTIDASE
4)		 4cs5 PROLIFERATING CELL
NUCLEAR ANTIGEN
(Litopenaeus
vannamei) 		3 / 3 PHE A 144
TYR A 249
TYR A 239
 None
 1.11A 4ffwA-4cs5A:
undetectable		 4ffwA-4cs5A:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_F_CAMF502_0
(CAMPHOR
5-MONOOXYGENASE)		 4cs5 PROLIFERATING CELL
NUCLEAR ANTIGEN
(Litopenaeus
vannamei) 		4 / 4 TYR A 249
THR A 219
VAL A 225
ILE A 247
 None
 1.33A 4jx1F-4cs5A:
undetectable		 4jx1F-4cs5A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_D_SAMD601_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 4cs5 PROLIFERATING CELL
NUCLEAR ANTIGEN
(Litopenaeus
vannamei) 		3 / 3 ASN A 120
ASP A  97
ASP A  94
 None
 0.87A 4obwD-4cs5A:
undetectable		 4obwD-4cs5A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TOA_B_ESTB601_1
(ESTROGEN RECEPTOR
BETA)		 4cs5 PROLIFERATING CELL
NUCLEAR ANTIGEN
(Litopenaeus
vannamei) 		5 / 12 LEU A  12
LEU A  11
ILE A 247
LEU A 221
LEU A  37
 None
 1.23A 5toaB-4cs5A:
undetectable		 5toaB-4cs5A:
24.73