SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4csq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ROX_B_T44B128_1
(TRANSTHYRETIN)		 4csq UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 GLU A  21
ALA A  17
LEU A  14
THR A  16
 None
 1.11A 2roxB-4csqA:
undetectable		 2roxB-4csqA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB202_1
(PROTEIN S100-A4)		 4csq UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 GLU A  34
LEU A  37
ASP A  38
 None
 0.36A 3ko0A-4csqA:
undetectable		 3ko0A-4csqA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_C_ZMRC1470_2
(NEURAMINIDASE)		 4csq UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 ARG A  29
ARG A  67
TRP A  28
 None
 1.41A 4cpzC-4csqA:
undetectable		 4cpzC-4csqA:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_E_ZMRE1471_2
(NEURAMINIDASE)		 4csq UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 ARG A  29
ARG A  67
TRP A  28
 None
 1.48A 4cpzE-4csqA:
undetectable		 4cpzE-4csqA:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_H_ZMRH1470_2
(NEURAMINIDASE)		 4csq UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 ARG A  29
ARG A  67
TRP A  28
 None
 1.45A 4cpzH-4csqA:
undetectable		 4cpzH-4csqA:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8V_B_MIYB1103_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 4csq UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 SER A  88
ASP A  23
ILE A  22
PHE A  30
VAL A  59
 None
 1.15A 4u8vB-4csqA:
undetectable		 4u8vB-4csqA:
7.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_C_GMJC301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 4csq UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 LEU A 103
ASP A  12
GLN A   7
GLU A  13
 None
 1.44A 6djzC-4csqA:
undetectable		 6djzC-4csqA:
21.40