SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4csu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CTR_A_TFPA153_1
(CALMODULIN)		 4csu GTPASE OBGE/CGTA
(Escherichia
coli) 		5 / 9 GLU 9 295
ILE 9 263
LEU 9 280
GLU 9 302
ALA 9 303
 None
 1.30A 1ctrA-4csu9:
undetectable		 1ctrA-4csu9:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IKE_A_HSMA190_1
(NITROPHORIN 4)		 4csu GTPASE OBGE/CGTA
(Escherichia
coli) 		3 / 3 ASP 9  98
LEU 9  10
LEU 9 152
 None
 0.76A 1ikeA-4csu9:
undetectable		 1ikeA-4csu9:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_B_HSMB304_1
(NITROPHORIN 1)		 4csu GTPASE OBGE/CGTA
(Escherichia
coli) 		3 / 3 ASP 9  98
LEU 9  10
LEU 9 152
 None
 0.75A 1np1B-4csu9:
undetectable		 1np1B-4csu9:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA502_0
(CHORISMATE SYNTHASE)		 4csu GTPASE OBGE/CGTA
(Escherichia
coli) 		3 / 3 GLY 9  36
ASP 9  35
SER 9  22
 U  B2555 ( 4.5A)
G  B2553 ( 2.7A)
None
 0.64A 2qhfA-4csu9:
undetectable		 2qhfA-4csu9:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RK8_A_PPFA3969_1
(PHOSPHOENOLPYRUVATE
CARBOXYKINASE,
CYTOSOLIC [GTP])		 4csu GTPASE OBGE/CGTA
(Escherichia
coli) 		4 / 8 LYS 9  89
HIS 9 111
ASP 9  50
ALA 9 160
 None
 1.11A 2rk8A-4csu9:
undetectable		 2rk8A-4csu9:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_P_TRPP1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4csu GTPASE OBGE/CGTA
(Escherichia
coli) 		4 / 7 GLY 9 163
VAL 9 211
ASP 9 213
ILE 9 214
 None
 0.85A 3fi0P-4csu9:
undetectable		 3fi0P-4csu9:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_A_ACRA602_1
(-)		 4csu GTPASE OBGE/CGTA
(Escherichia
coli) 		5 / 12 GLY 9  16
GLY 9  17
ASN 9  72
CYH 9  20
GLY 9  37
 None
 1.18A 6gneA-4csu9:
undetectable		 6gneA-4csu9:
21.30