SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ct3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		 4ct3 ORF30/ORF32
(Staphylococcus
virus
K) 		4 / 6 ILE A   8
ARG A  11
LEU A  12
LEU A  65
 None
GOL  A1168 (-3.7A)
None
None
 0.96A 2rlfA-4ct3A:
undetectable
2rlfD-4ct3A:
undetectable		 2rlfA-4ct3A:
16.46
2rlfD-4ct3A:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AF0_A_PAUA314_0
(PANTOTHENATE KINASE)		 4ct3 ORF30/ORF32
(Staphylococcus
virus
K) 		4 / 8 VAL A 163
LEU A  12
LYS A 101
GLY A 102
 None
 0.72A 3af0A-4ct3A:
undetectable		 3af0A-4ct3A:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EQM_A_ASDA601_1
(CYTOCHROME P450 19A1)		 4ct3 ORF30/ORF32
(Staphylococcus
virus
K) 		5 / 10 ILE A 159
ILE A 118
THR A  72
VAL A  70
LEU A  65
 None
CMH  A1166 (-4.7A)
None
None
None
 1.26A 3eqmA-4ct3A:
undetectable		 3eqmA-4ct3A:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S79_A_ASDA601_1
(CYTOCHROME P450 19A1)		 4ct3 ORF30/ORF32
(Staphylococcus
virus
K) 		5 / 12 ILE A 159
ILE A 118
THR A  72
VAL A  70
LEU A  65
 None
CMH  A1166 (-4.7A)
None
None
None
 1.26A 3s79A-4ct3A:
undetectable		 3s79A-4ct3A:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1001_1
(HEMOLYTIC LECTIN
CEL-III)		 4ct3 ORF30/ORF32
(Staphylococcus
virus
K) 		4 / 5 VAL A  38
GLY A  37
TYR A  32
ASP A  33
 None
 1.35A 3w9tA-4ct3A:
undetectable		 3w9tA-4ct3A:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB503_1
(HEMOLYTIC LECTIN
CEL-III)		 4ct3 ORF30/ORF32
(Staphylococcus
virus
K) 		4 / 5 VAL A  38
GLY A  37
TYR A  32
ASP A  33
 None
 1.34A 3w9tB-4ct3A:
undetectable		 3w9tB-4ct3A:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1001_1
(HEMOLYTIC LECTIN
CEL-III)		 4ct3 ORF30/ORF32
(Staphylococcus
virus
K) 		4 / 5 VAL A  38
GLY A  37
TYR A  32
ASP A  33
 None
 1.34A 3w9tC-4ct3A:
undetectable		 3w9tC-4ct3A:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD502_1
(HEMOLYTIC LECTIN
CEL-III)		 4ct3 ORF30/ORF32
(Staphylococcus
virus
K) 		4 / 5 VAL A  38
GLY A  37
TYR A  32
ASP A  33
 None
 1.35A 3w9tD-4ct3A:
undetectable		 3w9tD-4ct3A:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE504_1
(HEMOLYTIC LECTIN
CEL-III)		 4ct3 ORF30/ORF32
(Staphylococcus
virus
K) 		4 / 5 VAL A  38
GLY A  37
TYR A  32
ASP A  33
 None
 1.35A 3w9tE-4ct3A:
undetectable		 3w9tE-4ct3A:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF504_1
(HEMOLYTIC LECTIN
CEL-III)		 4ct3 ORF30/ORF32
(Staphylococcus
virus
K) 		4 / 5 VAL A  38
GLY A  37
TYR A  32
ASP A  33
 None
 1.35A 3w9tF-4ct3A:
undetectable		 3w9tF-4ct3A:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG504_1
(HEMOLYTIC LECTIN
CEL-III)		 4ct3 ORF30/ORF32
(Staphylococcus
virus
K) 		4 / 5 VAL A  38
GLY A  37
TYR A  32
ASP A  33
 None
 1.35A 3w9tG-4ct3A:
undetectable		 3w9tG-4ct3A:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI507_0
(RNA POLYMERASE
3D-POL)		 4ct3 ORF30/ORF32
(Staphylococcus
virus
K) 		3 / 3 LYS A  94
PRO A  95
SER A  96
 MMC  A1172 ( 4.3A)
None
None
 0.48A 4k50I-4ct3A:
undetectable		 4k50I-4ct3A:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQ8_A_ASDA602_1
(CYTOCHROME P450 19A1)		 4ct3 ORF30/ORF32
(Staphylococcus
virus
K) 		5 / 10 ILE A 159
ILE A 118
THR A  72
VAL A  70
LEU A  65
 None
CMH  A1166 (-4.7A)
None
None
None
 1.21A 4kq8A-4ct3A:
undetectable		 4kq8A-4ct3A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_F_377F401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4ct3 ORF30/ORF32
(Staphylococcus
virus
K) 		4 / 7 TYR A 152
LEU A 155
PHE A 130
ARG A 148
 None
 1.18A 4twdF-4ct3A:
undetectable
4twdJ-4ct3A:
undetectable		 4twdF-4ct3A:
18.24
4twdJ-4ct3A:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_G_377G401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4ct3 ORF30/ORF32
(Staphylococcus
virus
K) 		4 / 6 ARG A 148
TYR A 152
LEU A 155
PHE A 130
 None
 1.16A 4twdF-4ct3A:
undetectable
4twdG-4ct3A:
undetectable		 4twdF-4ct3A:
18.24
4twdG-4ct3A:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKV_A_ASDA602_1
(AROMATASE)		 4ct3 ORF30/ORF32
(Staphylococcus
virus
K) 		5 / 12 ILE A 159
ILE A 118
THR A  72
VAL A  70
LEU A  65
 None
CMH  A1166 (-4.7A)
None
None
None
 1.24A 5jkvA-4ct3A:
undetectable		 5jkvA-4ct3A:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKW_A_TESA601_1
(AROMATASE)		 4ct3 ORF30/ORF32
(Staphylococcus
virus
K) 		5 / 11 ILE A 159
ILE A 118
THR A  72
VAL A  70
LEU A  65
 None
CMH  A1166 (-4.7A)
None
None
None
 1.21A 5jkwA-4ct3A:
undetectable		 5jkwA-4ct3A:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JL6_A_ASDA601_1
(AROMATASE)		 4ct3 ORF30/ORF32
(Staphylococcus
virus
K) 		5 / 9 ILE A 159
ILE A 118
THR A  72
VAL A  70
LEU A  65
 None
CMH  A1166 (-4.7A)
None
None
None
 1.20A 5jl6A-4ct3A:
0.0		 5jl6A-4ct3A:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JL7_A_ASDA601_1
(AROMATASE)		 4ct3 ORF30/ORF32
(Staphylococcus
virus
K) 		5 / 10 ILE A 159
ILE A 118
THR A  72
VAL A  70
LEU A  65
 None
CMH  A1166 (-4.7A)
None
None
None
 1.25A 5jl7A-4ct3A:
undetectable		 5jl7A-4ct3A:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JL9_A_ASDA601_1
(AROMATASE)		 4ct3 ORF30/ORF32
(Staphylococcus
virus
K) 		5 / 9 ILE A 159
ILE A 118
THR A  72
VAL A  70
LEU A  65
 None
CMH  A1166 (-4.7A)
None
None
None
 1.25A 5jl9A-4ct3A:
undetectable		 5jl9A-4ct3A:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 4ct3 ORF30/ORF32
(Staphylococcus
virus
K) 		5 / 9 LEU A 155
GLY A 116
ILE A 118
PHE A 130
ILE A 132
 None
None
CMH  A1166 (-4.7A)
None
None
 1.34A 6ebpA-4ct3A:
undetectable		 6ebpA-4ct3A:
19.39