SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ct7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_E_ACTE3005_0
(BETA-CARBONIC
ANHYDRASE)		 4ct7 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 1
(Homo
sapiens) 		4 / 7 ASP A1565
GLY A1563
GLY A1562
GLN A1568
 None
 1.00A 1ekjE-4ct7A:
undetectable
1ekjF-4ct7A:
undetectable		 1ekjE-4ct7A:
20.63
1ekjF-4ct7A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3003_1
(SERUM ALBUMIN)		 4ct7 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 1
(Homo
sapiens) 		4 / 6 HIS A1373
ILE A1374
ALA A1496
VAL A1393
 None
 1.00A 1hk1A-4ct7A:
undetectable		 1hk1A-4ct7A:
17.38