SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4cu2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_C_VK3C202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 4cu2 ENDOLYSIN
(Clostridium
phage
phiCTP1) 		4 / 7 TYR A 269
TYR A 237
LEU A 213
ASN A 197
 None
 1.08A 4f8yC-4cu2A:
3.2
4f8yD-4cu2A:
3.3		 4f8yC-4cu2A:
23.33
4f8yD-4cu2A:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_B_PFLB510_1
(PROTON-GATED ION
CHANNEL)		 4cu2 ENDOLYSIN
(Clostridium
phage
phiCTP1) 		4 / 6 ALA A 210
LEU A 213
ILE A 254
TYR A 246
 None
 0.86A 5mvmB-4cu2A:
undetectable
5mvmC-4cu2A:
undetectable		 5mvmB-4cu2A:
14.46
5mvmC-4cu2A:
14.46