SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4cu9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AL4_A_DVAA6_0
(GRAMICIDIN D)		 4cu9 BETA-GALACTOSIDASE
(Streptococcus
pneumoniae) 		4 / 5 ALA A1876
VAL A1878
TRP A1975
TRP A1861
 None
 1.25A 1al4A-4cu9A:
undetectable
1al4B-4cu9A:
undetectable		 1al4A-4cu9A:
7.58
1al4B-4cu9A:
7.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_D_SAMD301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4cu9 BETA-GALACTOSIDASE
(Streptococcus
pneumoniae) 		3 / 3 ASP A1838
ASP A1848
ASN A1863
 None
 0.65A 2bm9D-4cu9A:
undetectable		 2bm9D-4cu9A:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_D_SAMD603_0
(HYPOTHETICAL PROTEIN)		 4cu9 BETA-GALACTOSIDASE
(Streptococcus
pneumoniae) 		5 / 12 GLY A1958
ALA A1900
ASP A1905
PHE A1898
ASP A1959
 None
 1.08A 2yvlD-4cu9A:
undetectable		 2yvlD-4cu9A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXV_D_MTXD2000_2
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 4cu9 BETA-GALACTOSIDASE
(Streptococcus
pneumoniae) 		3 / 3 LEU A1896
ARG A1976
ASN A1863
 None
 0.72A 3qxvD-4cu9A:
2.2		 3qxvD-4cu9A:
24.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_A_RBVA601_1
(RNA POLYMERASE)		 4cu9 BETA-GALACTOSIDASE
(Streptococcus
pneumoniae) 		5 / 9 THR A1836
THR A1862
ASN A1863
GLY A1985
ASP A1905
 None
 1.23A 3sfuA-4cu9A:
undetectable		 3sfuA-4cu9A:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_2
(ANDROGEN RECEPTOR)		 4cu9 BETA-GALACTOSIDASE
(Streptococcus
pneumoniae) 		4 / 6 LEU A1850
ASN A1851
MET A1977
VAL A1891
 None
 0.87A 4okbA-4cu9A:
undetectable		 4okbA-4cu9A:
20.70