SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4cuo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		 4cuo BANYAN PEROXIDASE
(Ficus
benghalensis) 		4 / 8 HIS A 169
GLY A 172
LEU A 243
ASP A 246
 HEM  A1307 (-3.3A)
HEM  A1307 (-3.3A)
HEM  A1307 ( 4.9A)
None
 0.43A 1aegA-4cuoA:
24.2		 1aegA-4cuoA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_D_CCSD47_0
(GLUTATHIONE
S-TRANSFERASE)		 4cuo BANYAN PEROXIDASE
(Ficus
benghalensis) 		4 / 7 THR A 245
GLY A 241
LEU A 220
TYR A 232
 HEM  A1307 (-3.5A)
None
None
None
 0.82A 1gtiD-4cuoA:
undetectable		 1gtiD-4cuoA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_E_CCSE47_0
(GLUTATHIONE
S-TRANSFERASE)		 4cuo BANYAN PEROXIDASE
(Ficus
benghalensis) 		4 / 7 THR A 245
GLY A 241
LEU A 220
TYR A 232
 HEM  A1307 (-3.5A)
None
None
None
 0.96A 1gtiE-4cuoA:
undetectable		 1gtiE-4cuoA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVS_B_MK1B902_3
(POL POLYPROTEIN)		 4cuo BANYAN PEROXIDASE
(Ficus
benghalensis) 		5 / 12 ALA A  86
VAL A  18
ILE A 100
VAL A  94
ILE A  17
 None
 1.10A 2avsB-4cuoA:
undetectable		 2avsB-4cuoA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_C_SAMC300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 4cuo BANYAN PEROXIDASE
(Ficus
benghalensis) 		4 / 4 SER A 112
GLY A 113
HIS A  40
ASP A  99
 None
 1.35A 2oxtC-4cuoA:
undetectable		 2oxtC-4cuoA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P16_A_GG2A298_2
(COAGULATION FACTOR X
(EC 3.4.21.6)
(STUART FACTOR)
(STUART-PROWER
FACTOR))		 4cuo BANYAN PEROXIDASE
(Ficus
benghalensis) 		3 / 3 ARG A 131
GLU A  64
GLN A  66
 NAG  A1308 ( 4.3A)
NA  A1328 ( 4.5A)
None
 1.03A 2p16A-4cuoA:
undetectable		 2p16A-4cuoA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFF_A_QPSA600_1
(BETA-AMYLASE)		 4cuo BANYAN PEROXIDASE
(Ficus
benghalensis) 		5 / 12 ALA A 134
GLU A  64
GLN A 155
SER A  52
GLY A  51
 None
NA  A1328 ( 4.5A)
None
NA  A1328 ( 2.1A)
None
 1.20A 2xffA-4cuoA:
undetectable		 2xffA-4cuoA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_B_DGXB1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 4cuo BANYAN PEROXIDASE
(Ficus
benghalensis) 		3 / 3 LEU A  54
VAL A  95
ARG A 296
 None
 0.88A 3b0wB-4cuoA:
undetectable		 3b0wB-4cuoA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BRF_A_SORA1_0
(LIN-12 AND GLP-1
PHENOTYPE PROTEIN 1,
ISOFORM A)		 4cuo BANYAN PEROXIDASE
(Ficus
benghalensis) 		3 / 3 GLY A  51
ASP A 125
SER A  96
 None
 0.67A 3brfA-4cuoA:
undetectable		 3brfA-4cuoA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4cuo BANYAN PEROXIDASE
(Ficus
benghalensis) 		4 / 8 PRO A  12
ASN A  13
VAL A  94
GLY A  93
 None
 0.69A 3em0B-4cuoA:
undetectable		 3em0B-4cuoA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_B_478B200_2
(HIV-1 PROTEASE)		 4cuo BANYAN PEROXIDASE
(Ficus
benghalensis) 		5 / 10 ALA A  86
VAL A  18
ILE A 100
VAL A  94
ILE A  17
 None
 1.05A 3oxvB-4cuoA:
undetectable		 3oxvB-4cuoA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_C_478C200_2
(HIV-1 PROTEASE)		 4cuo BANYAN PEROXIDASE
(Ficus
benghalensis) 		5 / 11 ALA A  86
VAL A  18
ILE A 100
VAL A  94
ILE A  17
 None
 1.03A 3oxvD-4cuoA:
undetectable		 3oxvD-4cuoA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_B_017B200_2
(HIV-1 PROTEASE)		 4cuo BANYAN PEROXIDASE
(Ficus
benghalensis) 		5 / 10 ALA A  86
VAL A  18
ILE A 100
VAL A  94
ILE A  17
 None
 0.98A 3oxwB-4cuoA:
undetectable		 3oxwB-4cuoA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_B_FLPB701_1
(CYCLOOXYGENASE-2)		 4cuo BANYAN PEROXIDASE
(Ficus
benghalensis) 		5 / 11 VAL A 287
LEU A 288
LEU A   2
GLY A  51
ALA A  98
 None
 1.22A 3pghB-4cuoA:
0.0		 3pghB-4cuoA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_A_SUZA201_1
(TRANSTHYRETIN)		 4cuo BANYAN PEROXIDASE
(Ficus
benghalensis) 		4 / 7 ALA A  34
LEU A  36
SER A 108
SER A 112
 HEM  A1307 (-3.7A)
None
None
None
 0.93A 4iklA-4cuoA:
undetectable
4iklB-4cuoA:
undetectable		 4iklA-4cuoA:
16.83
4iklB-4cuoA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_B_SUZB201_1
(TRANSTHYRETIN)		 4cuo BANYAN PEROXIDASE
(Ficus
benghalensis) 		4 / 8 SER A 112
ALA A  34
LEU A  36
SER A 108
 None
HEM  A1307 (-3.7A)
None
None
 0.95A 4iklA-4cuoA:
undetectable
4iklB-4cuoA:
undetectable		 4iklA-4cuoA:
16.83
4iklB-4cuoA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4cuo BANYAN PEROXIDASE
(Ficus
benghalensis) 		4 / 7 LEU A 148
THR A 159
LEU A 162
THR A 252
 None
NAG  A1325 (-3.0A)
None
None
 0.91A 4z90A-4cuoA:
undetectable
4z90B-4cuoA:
undetectable
4z90C-4cuoA:
undetectable
4z90D-4cuoA:
undetectable
4z90E-4cuoA:
undetectable		 4z90A-4cuoA:
22.03
4z90B-4cuoA:
22.03
4z90C-4cuoA:
22.03
4z90D-4cuoA:
22.03
4z90E-4cuoA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_G_SAMG301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 4cuo BANYAN PEROXIDASE
(Ficus
benghalensis) 		5 / 12 ALA A 174
GLN A 239
PHE A 179
GLY A 241
TYR A 240
 HEM  A1307 (-3.8A)
NAG  A1321 (-3.8A)
None
None
NAG  A1321 (-4.9A)
 1.40A 5hfjG-4cuoA:
undetectable		 5hfjG-4cuoA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQY_B_017B101_2
(PROTEASE E35D-DRV)		 4cuo BANYAN PEROXIDASE
(Ficus
benghalensis) 		5 / 7 GLY A  51
ALA A  98
ASP A  99
GLY A 283
ILE A 285
 None
None
None
CL  A1331 ( 4.7A)
CO3  A1336 ( 4.9A)
 1.30A 5kqyB-4cuoA:
undetectable		 5kqyB-4cuoA:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR1_B_017B101_2
(PROTEASE PR5-DRV)		 4cuo BANYAN PEROXIDASE
(Ficus
benghalensis) 		5 / 8 GLY A  51
ALA A  98
ASP A  99
GLY A 283
ILE A 285
 None
None
None
CL  A1331 ( 4.7A)
CO3  A1336 ( 4.9A)
 1.32A 5kr1B-4cuoA:
undetectable		 5kr1B-4cuoA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH6_A_017A104_0
(PROTEASE)		 4cuo BANYAN PEROXIDASE
(Ficus
benghalensis) 		5 / 12 ALA A  86
VAL A  18
ILE A 100
VAL A  94
ILE A  17
 None
 0.93A 6dh6A-4cuoA:
undetectable		 6dh6A-4cuoA:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MXT_A_K5YA1401_1
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		 4cuo BANYAN PEROXIDASE
(Ficus
benghalensis) 		3 / 3 ASP A  29
SER A 108
SER A 112
 None
 0.66A 6mxtA-4cuoA:
undetectable		 6mxtA-4cuoA:
20.17