SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4cw1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DZ8_B_CAMB502_0 (CYTOCHROME P450-CAM)	4cw1	MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I GLYCOPROTEIN HAPLOTYPE B14 (Gallus gallus)	5 / 9	TYR A 58 VAL A 34 GLY A 26 THR A 24 VAL A 66	None	1.13A	1dz8B-4cw1A: undetectable	1dz8B-4cw1A: 21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DZ9_B_CAMB502_0 (CYTOCHROME P450-CAM)	4cw1	MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I GLYCOPROTEIN HAPLOTYPE B14 (Gallus gallus)	5 / 9	TYR A 58 VAL A 34 GLY A 26 THR A 24 VAL A 66	None	1.13A	1dz9B-4cw1A: undetectable	1dz9B-4cw1A: 21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ECK_A_ILEA601_0 (JASMONIC ACID-AMIDO SYNTHETASE JAR1)	4cw1	MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I GLYCOPROTEIN HAPLOTYPE B14 (Gallus gallus)	4 / 6	ALA A 201 VAL A 257 TYR A 268 HIS A 202	None	1.07A	5eckA-4cw1A: undetectable	5eckA-4cw1A: 19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OV9_B_CVIB603_0 (ACETYLCHOLINESTERASE)	4cw1	MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I GLYCOPROTEIN HAPLOTYPE B14 (Gallus gallus)	4 / 7	TYR A 7 GLN A 9 HIS A 35 TYR A 168	None	1.44A	5ov9B-4cw1A: undetectable	5ov9B-4cw1A: 21.53

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DZ8_B_CAMB502_0","CYTOCHROME P450-CAM","4cw1","MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I GLYCOPROTEIN HAPLOTYPE B14","Gallus gallus",5,"TYR A  58;VAL A  34;GLY A  26;THR A  24;VAL A  66","None","1.13A","1dz8B-4cw1A:undetectable","1dz8B-4cw1A:21.25"],["1DZ9_B_CAMB502_0","CYTOCHROME P450-CAM","4cw1","MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I GLYCOPROTEIN HAPLOTYPE B14","Gallus gallus",5,"TYR A  58;VAL A  34;GLY A  26;THR A  24;VAL A  66","None","1.13A","1dz9B-4cw1A:undetectable","1dz9B-4cw1A:21.25"],["5ECK_A_ILEA601_0","JASMONIC ACID-AMIDO SYNTHETASE JAR1","4cw1","MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I GLYCOPROTEIN HAPLOTYPE B14","Gallus gallus",4,"ALA A 201;VAL A 257;TYR A 268;HIS A 202","None","1.07A","5eckA-4cw1A:undetectable","5eckA-4cw1A:19.00"],["5OV9_B_CVIB603_0","ACETYLCHOLINESTERASE","4cw1","MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I GLYCOPROTEIN HAPLOTYPE B14","Gallus gallus",4,"TYR A   7;GLN A   9;HIS A  35;TYR A 168","None","1.44A","5ov9B-4cw1A:undetectable","5ov9B-4cw1A:21.53"]]