SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4cw4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AXW_A_MTXA732_1
(THYMIDYLATE SYNTHASE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 177
ASP A 196
GLY A  12
TYR A 580
ALA A 584
 None
 1.00A 1axwA-4cw4A:
undetectable		 1axwA-4cw4A:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1B02_A_C2FA281_0
(PROTEIN (THYMIDYLATE
SYNTHASE))		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 11 LEU A 177
ASP A 196
GLY A  12
TYR A 580
ALA A 584
 None
 1.03A 1b02A-4cw4A:
undetectable		 1b02A-4cw4A:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_B_ADNB602_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  23
ASP A 581
ASP A 196
GLY A  17
PHE A  10
 None
 1.20A 1d4fB-4cw4A:
undetectable		 1d4fB-4cw4A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_C_ADNC603_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  23
ASP A 581
ASP A 196
GLY A  17
PHE A  10
 None
 1.23A 1d4fC-4cw4A:
undetectable		 1d4fC-4cw4A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_D_ADND604_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  23
ASP A 581
ASP A 196
GLY A  17
PHE A  10
 None
 1.19A 1d4fD-4cw4A:
undetectable		 1d4fD-4cw4A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_C_ACTC3004_0
(BETA-CARBONIC
ANHYDRASE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		4 / 6 GLN A 586
TYR A  59
VAL A  52
GLY A  44
 None
 0.98A 1ekjC-4cw4A:
undetectable
1ekjD-4cw4A:
undetectable		 1ekjC-4cw4A:
17.53
1ekjD-4cw4A:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_C_ACTC3007_0
(BETA-CARBONIC
ANHYDRASE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		4 / 6 VAL A  52
GLY A  44
GLN A 586
TYR A  59
 None
 0.99A 1ekjC-4cw4A:
undetectable
1ekjD-4cw4A:
undetectable		 1ekjC-4cw4A:
17.53
1ekjD-4cw4A:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HVY_D_D16D417_1
(THYMIDYLATE SYNTHASE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 177
ASP A 196
GLY A  12
TYR A 580
ALA A 584
 None
 1.03A 1hvyD-4cw4A:
undetectable		 1hvyD-4cw4A:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LII_A_ADNA699_2
(ADENOSINE KINASE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		4 / 4 SER A  20
LEU A 589
TYR A 580
GLY A  12
 None
 1.47A 1liiA-4cw4A:
undetectable		 1liiA-4cw4A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1872_0
(FPRA)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		4 / 5 SER A  19
ASN A  14
ALA A  16
ASP A 480
 None
 1.50A 1lqtA-4cw4A:
undetectable
1lqtB-4cw4A:
undetectable		 1lqtA-4cw4A:
22.81
1lqtB-4cw4A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 ILE A 389
PHE A 388
ALA A 540
THR A 385
LEU A 288
 None
 1.18A 1og5B-4cw4A:
undetectable		 1og5B-4cw4A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OPJ_B_STIB4_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		4 / 6 VAL A  47
ILE A  80
MET A  33
ARG A  58
 None
 1.10A 1opjB-4cw4A:
undetectable		 1opjB-4cw4A:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  23
ASP A 581
ASP A 196
GLY A  17
PHE A  10
 None
 1.24A 1v8bA-4cw4A:
undetectable		 1v8bA-4cw4A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  23
ASP A 581
ASP A 196
GLY A  24
PHE A  10
 None
 1.50A 1v8bA-4cw4A:
undetectable		 1v8bA-4cw4A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_B_ADNB1502_1
(ADENOSYLHOMOCYSTEINA
SE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  23
ASP A 581
ASP A 196
GLY A  17
PHE A  10
 None
 1.22A 1v8bB-4cw4A:
undetectable		 1v8bB-4cw4A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_C_ADNC2502_1
(ADENOSYLHOMOCYSTEINA
SE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  23
ASP A 581
ASP A 196
GLY A  17
PHE A  10
 None
 1.22A 1v8bC-4cw4A:
undetectable		 1v8bC-4cw4A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_C_ADNC2502_1
(ADENOSYLHOMOCYSTEINA
SE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  23
ASP A 581
ASP A 196
GLY A  24
PHE A  10
 None
 1.49A 1v8bC-4cw4A:
undetectable		 1v8bC-4cw4A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_D_ADND3502_1
(ADENOSYLHOMOCYSTEINA
SE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  23
ASP A 581
ASP A 196
GLY A  17
PHE A  10
 None
 1.22A 1v8bD-4cw4A:
2.3		 1v8bD-4cw4A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KCE_A_D16A566_1
(THYMIDYLATE SYNTHASE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 177
ASP A 196
GLY A  12
TYR A 580
ALA A 584
 None
 0.99A 2kceA-4cw4A:
undetectable		 2kceA-4cw4A:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KCE_B_D16B568_1
(THYMIDYLATE SYNTHASE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 177
ASP A 196
GLY A  12
TYR A 580
ALA A 584
 None
 0.99A 2kceB-4cw4A:
undetectable		 2kceB-4cw4A:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNJ_A_225A501_1
(CYTOCHROME P450 2C8)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 10 VAL A 219
ALA A 218
VAL A 212
ILE A 208
VAL A 209
 None
 0.96A 2nnjA-4cw4A:
undetectable		 2nnjA-4cw4A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1373_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		4 / 8 SER A 446
PHE A 350
VAL A 503
ASN A 353
 None
CL  A1636 (-4.5A)
None
CL  A1636 (-4.4A)
 1.18A 2wekA-4cw4A:
undetectable		 2wekA-4cw4A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1373_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		4 / 8 SER A 446
PHE A 350
VAL A 503
ASN A 353
 None
CL  A1636 (-4.5A)
None
CL  A1636 (-4.4A)
 1.18A 2wekB-4cw4A:
undetectable		 2wekB-4cw4A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_A_SAMA298_0
(PUTATIVE
MODIFICATION
METHYLASE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 SER A 276
PRO A 259
PHE A 220
GLY A 306
VAL A 366
 None
 1.15A 2zifA-4cw4A:
undetectable		 2zifA-4cw4A:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 11 VAL A 302
THR A 201
ILE A 203
LEU A 376
THR A 207
 None
 1.42A 3bexC-4cw4A:
undetectable
3bexD-4cw4A:
undetectable		 3bexC-4cw4A:
17.97
3bexD-4cw4A:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 10 LEU A 376
THR A 207
VAL A 302
THR A 201
ILE A 203
 None
 1.42A 3bexC-4cw4A:
undetectable
3bexD-4cw4A:
undetectable		 3bexC-4cw4A:
17.97
3bexD-4cw4A:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 10 VAL A 302
THR A 201
ILE A 203
LEU A 376
THR A 207
 None
 1.42A 3bexE-4cw4A:
undetectable
3bexF-4cw4A:
undetectable		 3bexE-4cw4A:
17.97
3bexF-4cw4A:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 11 LEU A 376
THR A 207
VAL A 302
THR A 201
ILE A 203
 None
 1.41A 3bexE-4cw4A:
undetectable
3bexF-4cw4A:
undetectable		 3bexE-4cw4A:
17.97
3bexF-4cw4A:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 11 VAL A 302
THR A 201
ILE A 203
LEU A 376
THR A 207
 None
 1.42A 3bf1C-4cw4A:
undetectable
3bf1D-4cw4A:
undetectable		 3bf1C-4cw4A:
17.97
3bf1D-4cw4A:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_C_ADNC438_1
(ADENOSYLHOMOCYSTEINA
SE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  23
ASP A 581
ASP A 196
GLY A  17
PHE A  10
 None
 1.24A 3g1uC-4cw4A:
undetectable		 3g1uC-4cw4A:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_D_ADND438_1
(ADENOSYLHOMOCYSTEINA
SE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  23
ASP A 581
ASP A 196
GLY A  17
PHE A  10
 None
 1.20A 3g1uD-4cw4A:
undetectable		 3g1uD-4cw4A:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP2_B_PNNB5002_0
(TRANSCRIPTIONAL
REGULATOR TCAR)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		4 / 5 ASN A  14
ALA A  16
ALA A  15
ARG A  87
 None
 1.43A 3kp2B-4cw4A:
1.6		 3kp2B-4cw4A:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP5_A_KANA2001_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 11 VAL A 365
ALA A 475
GLU A 309
SER A 473
ASN A  14
 None
 1.38A 3kp5A-4cw4A:
undetectable		 3kp5A-4cw4A:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_B_PZIB802_0
(GLUTAMATE RECEPTOR 2)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		3 / 3 SER A 239
ASP A 230
ASN A 231
 None
 0.99A 3lsfB-4cw4A:
undetectable
3lsfE-4cw4A:
undetectable		 3lsfB-4cw4A:
17.69
3lsfE-4cw4A:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_E_PZIE802_0
(GLUTAMATE RECEPTOR 2)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		3 / 3 ASP A 230
ASN A 231
SER A 239
 None
 1.01A 3lsfB-4cw4A:
undetectable
3lsfE-4cw4A:
undetectable		 3lsfB-4cw4A:
17.69
3lsfE-4cw4A:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OEZ_A_STIA601_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		4 / 5 VAL A  47
ILE A  80
MET A  33
ARG A  58
 None
 1.38A 3oezA-4cw4A:
undetectable		 3oezA-4cw4A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL6_A_NIMA614_1
(LACTOPEROXIDASE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		4 / 7 HIS A  23
GLU A  73
GLU A  40
PRO A  69
 None
 1.28A 3ql6A-4cw4A:
undetectable		 3ql6A-4cw4A:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA604_0
(GBAA_1210 PROTEIN)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		4 / 6 TYR A 364
GLY A 306
VAL A 219
SER A 221
 None
 0.96A 3tj7A-4cw4A:
undetectable
3tj7B-4cw4A:
undetectable		 3tj7A-4cw4A:
16.04
3tj7B-4cw4A:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC606_0
(GBAA_1210 PROTEIN)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		4 / 6 TYR A 364
GLY A 306
VAL A 219
SER A 221
 None
 0.97A 3tj7C-4cw4A:
undetectable
3tj7D-4cw4A:
undetectable		 3tj7C-4cw4A:
16.04
3tj7D-4cw4A:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_D_ACTD605_0
(GBAA_1210 PROTEIN)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		4 / 6 VAL A 219
SER A 221
TYR A 364
GLY A 306
 None
 0.98A 3tj7C-4cw4A:
undetectable
3tj7D-4cw4A:
undetectable		 3tj7C-4cw4A:
16.04
3tj7D-4cw4A:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V8V_A_SAMA801_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 ILE A 389
GLY A 542
SER A 541
THR A 408
LEU A 367
 None
 1.15A 3v8vA-4cw4A:
3.6		 3v8vA-4cw4A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_A_SAMA1281_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		4 / 6 HIS A 244
SER A 239
GLU A 315
ASP A 230
 None
 0.87A 4blvA-4cw4A:
undetectable		 4blvA-4cw4A:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_A_NCTA501_1
(CYTOCHROME P450 2A6)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		4 / 7 PHE A 617
ASN A 264
GLY A 269
ILE A 600
 None
 0.90A 4ejjA-4cw4A:
undetectable		 4ejjA-4cw4A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOG_D_C2FD302_0
(THYMIDYLATE SYNTHASE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 11 LEU A 177
ASP A 196
GLY A  12
TYR A 580
ALA A 584
 None
 1.01A 4fogD-4cw4A:
undetectable		 4fogD-4cw4A:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_A_ACTA303_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		3 / 3 TYR A 491
HIS A  23
ARG A  26
 None
 1.10A 4htfA-4cw4A:
undetectable		 4htfA-4cw4A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_A_ADNA401_2
(SUGAR KINASE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		4 / 4 SER A 362
ILE A 591
TYR A 364
PRO A 174
 None
 1.23A 4k8tA-4cw4A:
0.2		 4k8tA-4cw4A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_B_ADNB401_2
(SUGAR KINASE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		4 / 4 SER A 362
ILE A 591
TYR A 364
PRO A 174
 None
 1.23A 4k8tB-4cw4A:
0.0		 4k8tB-4cw4A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_B_ADNB402_2
(SUGAR KINASE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		4 / 4 SER A 362
ILE A 591
TYR A 364
PRO A 174
 None
 1.24A 4k93B-4cw4A:
0.0		 4k93B-4cw4A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_A_ADNA401_2
(SUGAR KINASE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		4 / 4 SER A 362
ILE A 591
TYR A 364
PRO A 174
 None
 1.25A 4k9cA-4cw4A:
0.0		 4k9cA-4cw4A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_A_ADNA401_2
(SUGAR KINASE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		4 / 4 SER A 362
ILE A 591
TYR A 364
PRO A 174
 None
 1.24A 4k9iA-4cw4A:
0.0		 4k9iA-4cw4A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_B_ADNB401_2
(SUGAR KINASE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		4 / 4 SER A 362
ILE A 591
TYR A 364
PRO A 174
 None
 1.23A 4k9iB-4cw4A:
0.3		 4k9iB-4cw4A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		4 / 4 SER A 362
ILE A 591
TYR A 364
PRO A 174
 None
 1.22A 4lbxA-4cw4A:
0.0		 4lbxA-4cw4A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		4 / 4 SER A 362
ILE A 591
TYR A 364
PRO A 174
 None
 1.20A 4lc4A-4cw4A:
0.0		 4lc4A-4cw4A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		4 / 4 SER A 362
ILE A 591
TYR A 364
PRO A 174
 None
 1.22A 4lc4B-4cw4A:
0.0		 4lc4B-4cw4A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LS7_A_1X9A504_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 ALA A 280
CYH A 281
HIS A 434
HIS A 472
PHE A 535
 None
 0.71A 4ls7A-4cw4A:
44.3		 4ls7A-4cw4A:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LS7_A_1X9A504_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		7 / 12 ALA A 280
GLU A 309
HIS A 434
HIS A 472
LEU A 474
GLY A 534
PHE A 535
 None
 0.72A 4ls7A-4cw4A:
44.3		 4ls7A-4cw4A:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LS7_B_1X9B503_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 ALA A 280
CYH A 281
HIS A 434
HIS A 472
PHE A 535
 None
 0.73A 4ls7A-4cw4A:
44.3
4ls7B-4cw4A:
44.4		 4ls7A-4cw4A:
24.23
4ls7B-4cw4A:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LS7_B_1X9B503_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		6 / 12 ALA A 280
HIS A 434
HIS A 472
LEU A 474
GLY A 534
PHE A 535
 None
 0.59A 4ls7A-4cw4A:
44.3
4ls7B-4cw4A:
44.4		 4ls7A-4cw4A:
24.23
4ls7B-4cw4A:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  23
ASP A 581
ASP A 196
GLY A  17
PHE A  10
 None
 1.22A 4pfjA-4cw4A:
undetectable		 4pfjA-4cw4A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  23
ASP A 581
ASP A 196
GLY A  17
PHE A  10
 None
 1.04A 4pfjB-4cw4A:
undetectable		 4pfjB-4cw4A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  23
ASP A 581
ASP A 196
GLY A  17
PHE A  10
 None
 1.17A 4pgfA-4cw4A:
undetectable		 4pgfA-4cw4A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  23
ASP A 581
ASP A 196
GLY A  17
PHE A  10
 None
 1.06A 4pgfB-4cw4A:
undetectable		 4pgfB-4cw4A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XNX_A_41XA707_1
(TRANSPORTER)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 11 ALA A  16
TYR A  13
GLY A  44
SER A  20
GLY A  24
 None
 1.22A 4xnxA-4cw4A:
undetectable		 4xnxA-4cw4A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_A_C2FA402_0
(THYMIDYLATE SYNTHASE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 11 LEU A 177
ASP A 196
GLY A  12
TYR A 580
ALA A 584
 None
 1.00A 5fctA-4cw4A:
undetectable		 5fctA-4cw4A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_A_ADNA501_1
(ADENOSYLHOMOCYSTEINA
SE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  23
ASP A 581
ASP A 196
GLY A  17
PHE A  10
 None
 1.22A 5hm8A-4cw4A:
undetectable		 5hm8A-4cw4A:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_B_ADNB501_1
(ADENOSYLHOMOCYSTEINA
SE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  23
ASP A 581
ASP A 196
GLY A  17
PHE A  10
 None
 1.23A 5hm8B-4cw4A:
undetectable		 5hm8B-4cw4A:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_C_ADNC501_1
(ADENOSYLHOMOCYSTEINA
SE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  23
ASP A 581
ASP A 196
GLY A  17
PHE A  10
 None
 1.23A 5hm8C-4cw4A:
undetectable		 5hm8C-4cw4A:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_D_ADND501_1
(ADENOSYLHOMOCYSTEINA
SE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  23
ASP A 581
ASP A 196
GLY A  17
PHE A  10
 None
 1.22A 5hm8D-4cw4A:
undetectable		 5hm8D-4cw4A:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_E_ADNE501_1
(ADENOSYLHOMOCYSTEINA
SE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  23
ASP A 581
ASP A 196
GLY A  17
PHE A  10
 None
 1.23A 5hm8E-4cw4A:
undetectable		 5hm8E-4cw4A:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_F_ADNF501_1
(ADENOSYLHOMOCYSTEINA
SE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  23
ASP A 581
ASP A 196
GLY A  17
PHE A  10
 None
 1.23A 5hm8F-4cw4A:
undetectable		 5hm8F-4cw4A:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_G_ADNG501_1
(ADENOSYLHOMOCYSTEINA
SE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  23
ASP A 581
ASP A 196
GLY A  17
PHE A  10
 None
 1.22A 5hm8G-4cw4A:
undetectable		 5hm8G-4cw4A:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_H_ADNH501_1
(ADENOSYLHOMOCYSTEINA
SE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  23
ASP A 581
ASP A 196
GLY A  17
PHE A  10
 None
 1.23A 5hm8H-4cw4A:
2.5		 5hm8H-4cw4A:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGI_A_ZITA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 ILE A 292
VAL A   6
ALA A 550
MET A 553
THR A 424
 None
 1.12A 5igiA-4cw4A:
undetectable		 5igiA-4cw4A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_B_FUAB1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		4 / 5 ILE A 304
LEU A 482
HIS A 381
VAL A   8
 None
 1.19A 5jmnB-4cw4A:
2.6		 5jmnB-4cw4A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_B_ACTB401_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT
N6-ADENOSINE-METHYLT
RANSFERASE SUBUNIT
METTL14)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		4 / 6 LEU A  42
ARG A  27
ARG A  26
ARG A  38
 None
 1.23A 5l6eA-4cw4A:
undetectable
5l6eB-4cw4A:
undetectable		 5l6eA-4cw4A:
18.68
5l6eB-4cw4A:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  23
ASP A 581
ASP A 196
GLY A  17
PHE A  10
 None
 1.22A 5m66A-4cw4A:
undetectable		 5m66A-4cw4A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_D_ADND502_1
(ADENOSYLHOMOCYSTEINA
SE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  23
ASP A 581
ASP A 196
GLY A  17
PHE A  10
 None
 1.22A 5m66D-4cw4A:
undetectable		 5m66D-4cw4A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_B_CVIB603_0
(ACETYLCHOLINESTERASE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		4 / 7 GLN A 363
ASP A 480
HIS A 432
TYR A 491
 None
 1.08A 5ov9B-4cw4A:
undetectable		 5ov9B-4cw4A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_A_ADNA502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  23
ASP A 581
ASP A 196
GLY A  17
PHE A  10
 None
 1.22A 5v96A-4cw4A:
undetectable		 5v96A-4cw4A:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_B_ADNB502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  23
ASP A 581
ASP A 196
GLY A  17
PHE A  10
 None
 1.20A 5v96B-4cw4A:
undetectable		 5v96B-4cw4A:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_C_ADNC502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  23
ASP A 581
ASP A 196
GLY A  17
PHE A  10
 None
 1.23A 5v96C-4cw4A:
undetectable		 5v96C-4cw4A:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_D_ADND502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  23
ASP A 581
ASP A 196
GLY A  17
PHE A  10
 None
 1.24A 5v96D-4cw4A:
2.0		 5v96D-4cw4A:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCG_A_08YA602_2
(CYTOCHROME P450 3A4)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		3 / 3 ARG A 583
ARG A  18
ARG A 578
 None
 0.86A 5vcgA-4cw4A:
undetectable		 5vcgA-4cw4A:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X66_D_MTXD402_1
(THYMIDYLATE SYNTHASE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 10 PHE A 220
ILE A 277
GLY A 222
ASN A 256
ALA A 477
 None
 1.34A 5x66D-4cw4A:
undetectable		 5x66D-4cw4A:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AK3_B_P2EB1201_1
(PROSTAGLANDIN E2
RECEPTOR EP3
SUBTYPE,SOLUBLE
CYTOCHROME B562)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		4 / 5 PRO A   5
VAL A 384
GLY A  11
VAL A 305
 None
 1.06A 6ak3B-4cw4A:
undetectable		 6ak3B-4cw4A:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6APH_A_ADNA501_1
(ADENOSYLHOMOCYSTEINA
SE)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  23
ASP A 581
ASP A 196
GLY A  17
PHE A  10
 None
 1.15A 6aphA-4cw4A:
undetectable		 6aphA-4cw4A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_A_ADNA502_1
(-)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  23
ASP A 581
ASP A 196
GLY A  17
PHE A  10
 None
 1.15A 6f3mA-4cw4A:
undetectable		 6f3mA-4cw4A:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_B_ADNB502_1
(-)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  23
ASP A 581
ASP A 196
GLY A  17
PHE A  10
 None
 1.15A 6f3mB-4cw4A:
undetectable		 6f3mB-4cw4A:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_C_ADNC502_1
(-)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  23
ASP A 581
ASP A 196
GLY A  17
PHE A  10
 None
 1.15A 6f3mC-4cw4A:
undetectable		 6f3mC-4cw4A:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_D_ADND502_1
(-)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  23
ASP A 581
ASP A 196
GLY A  17
PHE A  10
 None
 1.17A 6f3mD-4cw4A:
undetectable		 6f3mD-4cw4A:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_A_ADNA501_1
(-)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  23
ASP A 581
ASP A 196
GLY A  17
PHE A  10
 None
 1.19A 6gbnA-4cw4A:
undetectable		 6gbnA-4cw4A:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_B_ADNB501_1
(-)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  23
ASP A 581
ASP A 196
GLY A  17
PHE A  10
 None
 1.19A 6gbnB-4cw4A:
undetectable		 6gbnB-4cw4A:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_D_ADND501_1
(-)		 4cw4 BETA-KETOACYL
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  23
ASP A 581
ASP A 196
GLY A  17
PHE A  10
 None
 1.20A 6gbnD-4cw4A:
undetectable		 6gbnD-4cw4A:
23.67