SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4cyd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CD2_A_FOLA307_1
(DIHYDROFOLATE
REDUCTASE)		 4cyd PROBABLE
TRANSCRIPTION
REGULATOR
(Corynebacterium
glutamicum) 		3 / 3 GLU A   6
ILE A   7
ARG A 163
 None
 0.67A 1cd2A-4cydA:
undetectable		 1cd2A-4cydA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_L_CLML221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4cyd PROBABLE
TRANSCRIPTION
REGULATOR
PROBABLE EXPRESSION
TAG
(Corynebacterium
glutamicum;
synthetic
construct) 		5 / 12 CYH A  98
TYR F  -4
PHE F  -3
VAL A  58
PHE A  81
 None
 1.24A 3u9fJ-4cydA:
undetectable
3u9fL-4cydA:
undetectable		 3u9fJ-4cydA:
20.90
3u9fL-4cydA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_A_ADNA901_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 4cyd PROBABLE
TRANSCRIPTION
REGULATOR
(Corynebacterium
glutamicum) 		5 / 9 ARG A 204
GLY A 205
LEU A 222
ASP A 218
ILE A 216
 None
 1.40A 3wdmA-4cydA:
undetectable		 3wdmA-4cydA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WW7_A_ACTA303_0
(EKC/KEOPS COMPLEX
SUBUNIT BUD32)		 4cyd PROBABLE
TRANSCRIPTION
REGULATOR
(Corynebacterium
glutamicum) 		4 / 4 LEU A 126
VAL A 129
GLU A  83
ARG A 133
 None
None
CMP  A1228 (-2.6A)
CMP  A1228 (-4.4A)
 1.18A 4ww7A-4cydA:
undetectable		 4ww7A-4cydA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_D_ILED602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4cyd PROBABLE
TRANSCRIPTION
REGULATOR
(Corynebacterium
glutamicum) 		5 / 6 ILE A 183
ALA A 154
THR A 156
VAL A 153
VAL A 214
 None
None
GOL  A1230 ( 4.8A)
None
None
 1.46A 5eclD-4cydA:
undetectable		 5eclD-4cydA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CK2_C_IPHC101_0
(INSULIN A CHAIN
INSULIN B CHAIN)		 4cyd PROBABLE
TRANSCRIPTION
REGULATOR
(Corynebacterium
glutamicum) 		4 / 4 ILE A 207
LEU A 158
HIS A 221
ALA A 223
 None
 1.01A 6ck2C-4cydA:
undetectable
6ck2D-4cydA:
undetectable		 6ck2C-4cydA:
8.09
6ck2D-4cydA:
6.67