SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4cyv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_B_URFB999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 4cyv HEMAGGLUTININ
(Influenza
A
virus) 		4 / 7 MET B 115
ALA B 111
ILE B   6
ILE B  10
 None
 0.93A 1upfB-4cyvB:
undetectable		 1upfB-4cyvB:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1162_1
(ALLERGEN ARG R 1)		 4cyv HEMAGGLUTININ
(Influenza
A
virus) 		3 / 3 GLU B 164
HIS B 142
GLU B 165
 None
 0.64A 2x45B-4cyvB:
undetectable		 2x45B-4cyvB:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1162_1
(ALLERGEN ARG R 1)		 4cyv HEMAGGLUTININ
(Influenza
A
virus) 		3 / 3 GLU B 164
HIS B 142
GLU B 165
 None
 0.62A 2x45C-4cyvB:
undetectable		 2x45C-4cyvB:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_B_SAMB801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 4cyv HEMAGGLUTININ
(Influenza
A
virus) 		4 / 8 ILE B 152
ASN B 154
TYR B 157
SER B 147
 None
NAG  B 211 (-1.9A)
None
None
 1.11A 2zw9B-4cyvB:
undetectable		 2zw9B-4cyvB:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PS9_A_SAMA670_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 4cyv HEMAGGLUTININ
(Influenza
A
virus) 		5 / 12 PHE B 138
ILE B  10
GLY B  23
PHE B  24
MET B 115
 None
 1.41A 3ps9A-4cyvB:
undetectable		 3ps9A-4cyvB:
12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_1
(ANDROGEN RECEPTOR)		 4cyv HEMAGGLUTININ
(Influenza
A
virus) 		5 / 12 GLY B  23
GLN B  34
MET B  17
VAL B  18
MET B 115
 None
 1.36A 4olmA-4cyvB:
undetectable		 4olmA-4cyvB:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDC_A_DEXA1778_2
(GLUCOCORTICOID
RECEPTOR)		 4cyv HEMAGGLUTININ
(Influenza
A
virus) 		3 / 3 MET B 115
GLN B  42
TYR B  38
 None
 0.82A 4udcA-4cyvB:
undetectable		 4udcA-4cyvB:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_ACTA608_0
(SERUM ALBUMIN)		 4cyv HEMAGGLUTININ
(Influenza
A
virus) 		3 / 3 LYS B 124
ARG B 127
HIS B 159
 None
 1.00A 4zbrA-4cyvB:
undetectable		 4zbrA-4cyvB:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_A_EY4A502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 4cyv HEMAGGLUTININ
(Influenza
A
virus) 		4 / 7 ALA B  96
THR B  93
TYR B  94
VAL B 100
 None
 0.92A 6cduA-4cyvB:
undetectable
6cduE-4cyvB:
2.0		 6cduA-4cyvB:
19.94
6cduE-4cyvB:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_H_EY4H500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 4cyv HEMAGGLUTININ
(Influenza
A
virus) 		4 / 7 VAL B 100
ALA B  96
THR B  93
TYR B  94
 None
 0.92A 6cduH-4cyvB:
undetectable
6cduI-4cyvB:
undetectable		 6cduH-4cyvB:
19.94
6cduI-4cyvB:
19.94