SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4czd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WU8_C_ADNC502_1
(HYPOTHETICAL PROTEIN
PH0463)		 4czd PUTATIVE
TRANSCRIPTIONAL
REGULATOR, ASNC
FAMILY
(Desulfovibrio
desulfuricans) 		4 / 7 PHE A 127
ASN A 116
ASN A 124
VAL A 150
 None
 1.37A 1wu8A-4czdA:
undetectable
1wu8C-4czdA:
undetectable		 1wu8A-4czdA:
18.59
1wu8C-4czdA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZUC_B_T98B202_1
(PROGESTERONE
RECEPTOR)		 4czd PUTATIVE
TRANSCRIPTIONAL
REGULATOR, ASNC
FAMILY
(Desulfovibrio
desulfuricans) 		5 / 12 LEU B  48
LEU B  45
LEU B  42
MET B  36
LEU B  30
 None
 1.27A 1zucB-4czdB:
undetectable		 1zucB-4czdB:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_D_SUED1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 4czd PUTATIVE
TRANSCRIPTIONAL
REGULATOR, ASNC
FAMILY
(Desulfovibrio
desulfuricans) 		3 / 3 TYR B 111
LEU A 160
LYS A 159
 None
 0.69A 3sueD-4czdB:
undetectable		 3sueD-4czdB:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_A_9PLA501_1
(CYTOCHROME P450 2A6)		 4czd PUTATIVE
TRANSCRIPTIONAL
REGULATOR, ASNC
FAMILY
(Desulfovibrio
desulfuricans) 		5 / 10 PHE B 158
VAL B  12
PHE B   5
ILE B  54
PHE A  79
 None
 1.27A 3t3qA-4czdB:
undetectable		 3t3qA-4czdB:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_B_9PLB501_1
(CYTOCHROME P450 2A6)		 4czd PUTATIVE
TRANSCRIPTIONAL
REGULATOR, ASNC
FAMILY
(Desulfovibrio
desulfuricans) 		5 / 10 PHE B 158
VAL B  12
PHE B   5
ILE B  54
PHE A  79
 None
 1.27A 3t3qB-4czdB:
undetectable		 3t3qB-4czdB:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_C_9PLC501_1
(CYTOCHROME P450 2A6)		 4czd PUTATIVE
TRANSCRIPTIONAL
REGULATOR, ASNC
FAMILY
(Desulfovibrio
desulfuricans) 		5 / 10 PHE B 158
VAL B  12
PHE B   5
ILE B  54
PHE A  79
 None
 1.26A 3t3qC-4czdB:
undetectable		 3t3qC-4czdB:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_D_9PLD501_1
(CYTOCHROME P450 2A6)		 4czd PUTATIVE
TRANSCRIPTIONAL
REGULATOR, ASNC
FAMILY
(Desulfovibrio
desulfuricans) 		5 / 10 PHE B 158
VAL B  12
PHE B   5
ILE B  54
PHE A  79
 None
 1.26A 3t3qD-4czdB:
undetectable		 3t3qD-4czdB:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4czd PUTATIVE
TRANSCRIPTIONAL
REGULATOR, ASNC
FAMILY
PUTATIVE
TRANSCRIPTIONAL
REGULATOR, ASNC
FAMILY
(Desulfovibrio
desulfuricans;
Desulfovibrio
desulfuricans) 		4 / 6 LEU A  40
PHE A  38
PHE B  57
LEU B  45
 None
 1.04A 3wg7C-4czdA:
undetectable
3wg7J-4czdA:
undetectable		 3wg7C-4czdA:
22.56
3wg7J-4czdA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F3T_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 4czd PUTATIVE
TRANSCRIPTIONAL
REGULATOR, ASNC
FAMILY
PUTATIVE
TRANSCRIPTIONAL
REGULATOR, ASNC
FAMILY
(Desulfovibrio
desulfuricans;
Desulfovibrio
desulfuricans) 		4 / 6 LEU A  40
LEU B  42
GLU B  38
TYR B  27
 None
 1.06A 4f3tA-4czdA:
undetectable		 4f3tA-4czdA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_A_CLQA303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4czd PUTATIVE
TRANSCRIPTIONAL
REGULATOR, ASNC
FAMILY
PUTATIVE
TRANSCRIPTIONAL
REGULATOR, ASNC
FAMILY
(Desulfovibrio
desulfuricans;
Desulfovibrio
desulfuricans) 		5 / 12 GLY A  76
GLY B  58
VAL B  12
PHE A  79
ILE B  54
 None
 1.09A 4fglA-4czdA:
undetectable
4fglB-4czdA:
undetectable		 4fglA-4czdA:
20.43
4fglB-4czdA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XR4_B_AG2B511_1
(HOMOSPERMIDINE
SYNTHASE)		 4czd PUTATIVE
TRANSCRIPTIONAL
REGULATOR, ASNC
FAMILY
(Desulfovibrio
desulfuricans) 		3 / 3 VAL B  12
PHE B   5
ARG B  47
 None
 0.84A 4xr4B-4czdB:
undetectable		 4xr4B-4czdB:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWV_A_ACAA18_2
(SCRFP-TAG,GP41)		 4czd PUTATIVE
TRANSCRIPTIONAL
REGULATOR, ASNC
FAMILY
(Desulfovibrio
desulfuricans) 		4 / 7 GLN A  97
ASP A 122
TRP A 126
LEU B 144
 None
 1.11A 5nwvA-4czdA:
undetectable		 5nwvA-4czdA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXC_A_ZITA306_1
(PREDICTED
AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 4czd PUTATIVE
TRANSCRIPTIONAL
REGULATOR, ASNC
FAMILY
(Desulfovibrio
desulfuricans) 		4 / 7 THR A  36
ARG B  56
PHE B  57
LEU A  40
 None
 1.19A 5uxcA-4czdA:
undetectable		 5uxcA-4czdA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 4czd PUTATIVE
TRANSCRIPTIONAL
REGULATOR, ASNC
FAMILY
PUTATIVE
TRANSCRIPTIONAL
REGULATOR, ASNC
FAMILY
(Desulfovibrio
desulfuricans;
Desulfovibrio
desulfuricans) 		4 / 5 LEU A  40
PHE A  38
PHE B  57
LEU B  45
 None
 1.12A 5x1bP-4czdA:
undetectable		 5x1bP-4czdA:
22.56