SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4czp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4002_1
(SERUM ALBUMIN)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		3 / 3 PHE A 190
LEU A 170
SER A 245
 None
HEM  A1374 (-4.6A)
HEM  A1374 (-3.3A)
 0.93A 1e7aA-4czpA:
undetectable		 1e7aA-4czpA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KB9_A_PCFA514_0
(CYTOCHROME B
CYTOCHROME C1, HEME
PROTEIN
UBIQUINOL-CYTOCHROME
C REDUCTASE COMPLEX
CORE PROTEIN I
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		4 / 8 SER A 150
ILE A 141
VAL A 166
SER A 172
 None
None
None
HEM  A1374 (-3.1A)
 1.07A 1kb9A-4czpA:
undetectable
1kb9C-4czpA:
undetectable
1kb9D-4czpA:
undetectable
1kb9E-4czpA:
undetectable		 1kb9A-4czpA:
20.94
1kb9C-4czpA:
21.88
1kb9D-4czpA:
21.77
1kb9E-4czpA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L2I_A_CCSA417_0
(ESTROGEN RECEPTOR)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		3 / 3 GLU A 295
LYS A  -1
VAL A   9
 None
 0.91A 1l2iA-4czpA:
undetectable		 1l2iA-4czpA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC685_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		4 / 8 ALA A 135
GLU A  74
ASP A  84
ILE A  91
 None
CA  A1371 ( 4.5A)
None
None
 0.89A 1p7lD-4czpA:
undetectable		 1p7lD-4czpA:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC885_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		4 / 8 ALA A 135
GLU A  74
ASP A  84
ILE A  91
 None
CA  A1371 ( 4.5A)
None
None
 0.89A 1p7lC-4czpA:
undetectable		 1p7lC-4czpA:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_A_DIFA701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		5 / 10 VAL A  28
VAL A 112
GLY A 110
ALA A 109
LEU A  90
 None
 1.12A 1pxxA-4czpA:
undetectable		 1pxxA-4czpA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_A_SAMA385_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		4 / 8 ALA A 135
GLU A  74
ASP A  84
ILE A  91
 None
CA  A1371 ( 4.5A)
None
None
 0.89A 1rg9B-4czpA:
undetectable		 1rg9B-4czpA:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_B_SAMB485_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		4 / 8 ALA A 135
GLU A  74
ASP A  84
ILE A  91
 None
CA  A1371 ( 4.5A)
None
None
 0.88A 1rg9A-4czpA:
undetectable		 1rg9A-4czpA:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC585_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		4 / 8 ALA A 135
GLU A  74
ASP A  84
ILE A  91
 None
CA  A1371 ( 4.5A)
None
None
 0.89A 1rg9D-4czpA:
undetectable		 1rg9D-4czpA:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC685_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		4 / 8 ALA A 135
GLU A  74
ASP A  84
ILE A  91
 None
CA  A1371 ( 4.5A)
None
None
 0.89A 1rg9C-4czpA:
undetectable		 1rg9C-4czpA:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		4 / 6 VAL A 222
SER A 223
ARG A 242
HIS A 251
 GOL  A1375 ( 4.5A)
GOL  A1375 (-3.3A)
GOL  A1375 (-3.8A)
None
 1.30A 2f8dA-4czpA:
undetectable		 2f8dA-4czpA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJP_A_KLNA413_1
(CYTOCHROME P450
113A1)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		5 / 12 PRO A 144
ALA A 281
LEU A 283
ALA A  63
ILE A 141
 HEM  A1374 (-4.1A)
None
None
None
None
 1.18A 2jjpA-4czpA:
undetectable		 2jjpA-4czpA:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_4
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		4 / 5 ALA A  37
ALA A 120
GLN A  25
VAL A 297
 None
 0.81A 2nyrB-4czpA:
undetectable		 2nyrB-4czpA:
24.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0Z_O_C41O1327_2
(RENIN)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		4 / 8 SER A 245
PRO A 225
LEU A 226
THR A 255
 HEM  A1374 (-3.3A)
None
None
None
 1.07A 2v0zO-4czpA:
undetectable		 2v0zO-4czpA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_B_QPSB1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		5 / 10 VAL A 106
SER A  80
GLY A  62
ALA A  48
GLN A 107
 None
None
CA  A1371 (-4.2A)
None
None
 1.38A 2x2iB-4czpA:
undetectable		 2x2iB-4czpA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_B_VD3B700_1
(CYTOCHROME P450 2R1)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		6 / 12 LEU A  29
ASN A 116
PHE A 108
VAL A 296
GLY A  21
THR A  44
 None
 1.46A 3c6gB-4czpA:
undetectable		 3c6gB-4czpA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_A_SAMA201_0
(YAEB-LIKE PROTEIN
RPA0152)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		5 / 12 LEU A 228
PRO A 227
GLY A 229
THR A 231
SER A 232
 None
 1.31A 3okxA-4czpA:
undetectable		 3okxA-4czpA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_1
(YAEB-LIKE PROTEIN
RPA0152)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		5 / 12 LEU A 228
PRO A 227
GLY A 229
THR A 231
SER A 232
 None
 1.33A 3okxB-4czpA:
undetectable		 3okxB-4czpA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXV_E_MTXE2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		5 / 12 ALA A 111
ARG A 122
SER A 294
ARG A 129
ALA A 278
 None
 1.17A 3qxvE-4czpA:
undetectable		 3qxvE-4czpA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_C_9PLC501_1
(CYTOCHROME P450 2E1)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		4 / 5 PHE A 161
ALA A 281
THR A  44
LEU A 169
 None
None
None
HEM  A1374 ( 3.9A)
 1.21A 3t3zC-4czpA:
undetectable		 3t3zC-4czpA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_A_IMNA701_1
(CYCLOOXYGENASE-2)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		5 / 12 VAL A  28
VAL A 112
GLY A 110
ALA A 109
LEU A  90
 None
 1.08A 4coxA-4czpA:
undetectable		 4coxA-4czpA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_B_IMNB701_1
(CYCLOOXYGENASE-2)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		5 / 12 VAL A  28
VAL A 112
GLY A 110
ALA A 109
LEU A  90
 None
 1.07A 4coxB-4czpA:
undetectable		 4coxB-4czpA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_C_IMNC701_1
(CYCLOOXYGENASE-2)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		5 / 12 VAL A  28
VAL A 112
GLY A 110
ALA A 109
LEU A  90
 None
 1.07A 4coxC-4czpA:
undetectable		 4coxC-4czpA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_D_IMND701_1
(CYCLOOXYGENASE-2)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		5 / 12 VAL A  28
VAL A 112
GLY A 110
ALA A 109
LEU A  90
 None
 1.09A 4coxD-4czpA:
undetectable		 4coxD-4czpA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_A_ACTA304_0
(GLUTATHIONE
TRANSFERASE GTE1)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		4 / 5 ALA A 361
ILE A  91
LEU A  68
ASN A  88
 None
 1.13A 4g19A-4czpA:
undetectable		 4g19A-4czpA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_J_KANJ301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		4 / 6 ASP A 186
ASP A 363
ASP A  85
GLU A  35
 None
None
MN  A1373 (-2.7A)
MN  A1372 ( 2.6A)
 1.25A 4gkhJ-4czpA:
undetectable		 4gkhJ-4czpA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		4 / 8 ALA A 135
GLU A  74
ASP A  84
ILE A  91
 None
CA  A1371 ( 4.5A)
None
None
 0.92A 4ndnB-4czpA:
undetectable		 4ndnB-4czpA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_C_SAMC405_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		4 / 8 ALA A 135
GLU A  74
ASP A  84
ILE A  91
 None
CA  A1371 ( 4.5A)
None
None
 0.92A 4ndnD-4czpA:
undetectable		 4ndnD-4czpA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8Z_A_BBIA402_1
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-3,
MITOCHONDRIAL)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		4 / 5 PHE A 202
HIS A 173
LEU A 243
PRO A 144
 None
HEM  A1374 (-3.5A)
HEM  A1374 ( 4.7A)
HEM  A1374 (-4.1A)
 1.38A 4o8zA-4czpA:
undetectable		 4o8zA-4czpA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTY_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		5 / 12 VAL A  28
VAL A 112
GLY A 110
ALA A 109
LEU A  90
 None
 1.10A 4otyA-4czpA:
undetectable		 4otyA-4czpA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTY_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		5 / 12 VAL A  28
VAL A 112
GLY A 110
ALA A 109
LEU A  90
 None
 1.08A 4otyB-4czpA:
0.0		 4otyB-4czpA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		5 / 12 VAL A  28
VAL A 112
GLY A 110
ALA A 109
LEU A  90
 None
 1.03A 4rrwA-4czpA:
1.3		 4rrwA-4czpA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		5 / 12 VAL A  28
VAL A 112
GLY A 110
ALA A 109
LEU A  90
 None
 1.03A 4rrwB-4czpA:
undetectable		 4rrwB-4czpA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_C_LURC705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		5 / 12 VAL A  28
VAL A 112
GLY A 110
ALA A 109
LEU A  90
 None
 1.04A 4rrwC-4czpA:
undetectable		 4rrwC-4czpA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_D_LURD705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		5 / 12 VAL A  28
VAL A 112
GLY A 110
ALA A 109
LEU A  90
 None
 1.03A 4rrwD-4czpA:
4.2		 4rrwD-4czpA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_A_LURA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		5 / 12 VAL A  28
VAL A 112
GLY A 110
ALA A 109
LEU A  90
 None
 1.06A 4rrxA-4czpA:
undetectable		 4rrxA-4czpA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_B_LURB706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		5 / 12 VAL A  28
VAL A 112
GLY A 110
ALA A 109
LEU A  90
 None
 1.06A 4rrxB-4czpA:
undetectable		 4rrxB-4czpA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		5 / 12 VAL A  28
VAL A 112
GLY A 110
ALA A 109
LEU A  90
 None
 1.03A 4rrzA-4czpA:
1.3		 4rrzA-4czpA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		5 / 12 VAL A  28
VAL A 112
GLY A 110
ALA A 109
LEU A  90
 None
 1.03A 4rrzB-4czpA:
undetectable		 4rrzB-4czpA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_C_LURC705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		5 / 12 VAL A  28
VAL A 112
GLY A 110
ALA A 109
LEU A  90
 None
 1.04A 4rrzC-4czpA:
undetectable		 4rrzC-4czpA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_D_LURD705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		5 / 12 VAL A  28
VAL A 112
GLY A 110
ALA A 109
LEU A  90
 None
 1.03A 4rrzD-4czpA:
4.2		 4rrzD-4czpA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		4 / 7 PHE A  45
SER A 172
ALA A 276
LEU A 280
 HEM  A1374 (-3.7A)
HEM  A1374 (-3.1A)
None
None
 1.10A 4xk8A-4czpA:
undetectable		 4xk8A-4czpA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YPM_A_BO2A801_1
(LON PROTEASE)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		5 / 12 LYS A  54
GLY A  56
PRO A  57
SER A  58
ALA A  59
 None
 0.99A 4ypmA-4czpA:
undetectable		 4ypmA-4czpA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_A_JMSA602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		5 / 12 VAL A  28
VAL A 112
GLY A 110
ALA A 109
LEU A  90
 None
 1.10A 5ikqA-4czpA:
undetectable		 5ikqA-4czpA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_B_JMSB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		5 / 12 VAL A  28
VAL A 112
GLY A 110
ALA A 109
LEU A  90
 None
 1.08A 5ikqB-4czpA:
undetectable		 5ikqB-4czpA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_A_ID8A601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		5 / 12 VAL A  28
LEU A  29
VAL A 112
GLY A 110
ALA A 109
 None
 1.10A 5ikrA-4czpA:
undetectable		 5ikrA-4czpA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_A_ID8A601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		5 / 12 VAL A  28
VAL A 112
GLY A 110
ALA A 109
LEU A  90
 None
 1.07A 5ikrA-4czpA:
undetectable		 5ikrA-4czpA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		5 / 12 VAL A  28
VAL A 112
GLY A 110
ALA A 109
LEU A  90
 None
 1.06A 5ikrB-4czpA:
undetectable		 5ikrB-4czpA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_A_TLFA601_0
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		5 / 12 VAL A  28
VAL A 112
GLY A 110
ALA A 109
LEU A  90
 None
 1.09A 5iktA-4czpA:
undetectable		 5iktA-4czpA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		5 / 12 VAL A  28
VAL A 112
GLY A 110
ALA A 109
LEU A  90
 None
 1.12A 5kirB-4czpA:
undetectable		 5kirB-4czpA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_B_SAMB304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		5 / 10 LEU A  29
GLY A  21
ILE A  41
SER A 115
LEU A 114
 None
None
HEM  A1374 ( 4.0A)
None
None
 0.98A 5l0zB-4czpA:
undetectable		 5l0zB-4czpA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		4 / 8 ASP A  36
SER A 115
ASN A 116
SER A  86
 None
 1.12A 5l1fA-4czpA:
undetectable
5l1fB-4czpA:
undetectable		 5l1fA-4czpA:
19.70
5l1fB-4czpA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_A_EPAA502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		5 / 10 PRO A 142
LEU A 152
ARG A 254
PRO A 253
VAL A 167
 HEM  A1374 ( 4.8A)
None
None
None
None
 1.41A 5m0oA-4czpA:
undetectable		 5m0oA-4czpA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		4 / 8 ALA A 135
GLU A  74
ASP A  84
ILE A  91
 None
CA  A1371 ( 4.5A)
None
None
 0.94A 5t8sA-4czpA:
undetectable		 5t8sA-4czpA:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 4czp EXTRALONG MANGANESE
PEROXIDASE
(Gelatoporia
subvermispora) 		4 / 7 ALA A 135
GLU A  74
ASP A  84
ILE A  91
 None
CA  A1371 ( 4.5A)
None
None
 0.90A 6fbnA-4czpA:
undetectable		 6fbnA-4czpA:
23.25