SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4czw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_A_ESTA351_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		5 / 12 VAL A 845
LEU A 663
PRO A 842
TYR A 665
LEU A 736
 None
 1.04A 1fduA-4czwA:
undetectable		 1fduA-4czwA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_B_ESTB354_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		4 / 8 VAL A 845
LEU A 663
PRO A 842
TYR A 665
 None
 0.93A 1fduB-4czwA:
undetectable		 1fduB-4czwA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9G_A_SAMA301_1
(HYPOTHETICAL PROTEIN
RV2118C)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		3 / 3 GLU A 497
HIS A 556
ASP A 481
 None
 0.63A 1i9gA-4czwA:
undetectable		 1i9gA-4czwA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWI_A_CAMA418_0
(CYTOCHROME P450-CAM)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		4 / 8 THR A 593
LEU A 508
VAL A 511
VAL A 721
 None
 0.74A 1iwiA-4czwA:
undetectable		 1iwiA-4czwA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		4 / 6 HIS A 513
ALA A 806
GLY A 804
TYR A 514
 None
 0.98A 1l5qA-4czwA:
undetectable		 1l5qA-4czwA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		4 / 6 HIS A 513
ALA A 806
GLY A 804
TYR A 514
 None
 0.98A 1l5qB-4czwA:
undetectable		 1l5qB-4czwA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		4 / 6 HIS A 513
ALA A 806
GLY A 804
TYR A 514
 None
 1.00A 1l7xA-4czwA:
undetectable		 1l7xA-4czwA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		4 / 6 HIS A 513
ALA A 806
GLY A 804
TYR A 514
 None
 1.01A 1l7xB-4czwA:
undetectable		 1l7xB-4czwA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		5 / 10 THR A 593
LEU A 508
VAL A 511
THR A 515
VAL A 721
 None
 1.02A 1o76A-4czwA:
undetectable		 1o76A-4czwA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T85_A_CAMA422_0
(CYTOCHROME P450-CAM)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		4 / 7 THR A 593
LEU A 508
VAL A 511
VAL A 721
 None
 0.73A 1t85A-4czwA:
undetectable		 1t85A-4czwA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		4 / 7 THR A 593
LEU A 508
VAL A 511
VAL A 721
 None
 0.75A 1t87A-4czwA:
undetectable		 1t87A-4czwA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_A_CAMA1416_0
(CYTOCHROME P450-CAM)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		4 / 8 THR A 593
LEU A 508
VAL A 511
THR A 515
 None
 0.98A 1uyuA-4czwA:
undetectable		 1uyuA-4czwA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRC_A_CAMA420_0
(CYTOCHROME P450-CAM)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		4 / 7 THR A 593
LEU A 508
VAL A 511
VAL A 721
 None
 0.77A 1yrcA-4czwA:
undetectable		 1yrcA-4czwA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRD_A_CAMA420_0
(CYTOCHROME P450-CAM)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		4 / 7 THR A 593
LEU A 508
VAL A 511
VAL A 721
 None
 0.76A 1yrdA-4czwA:
undetectable		 1yrdA-4czwA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1N_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		5 / 11 THR A 593
LEU A 508
VAL A 511
THR A 515
VAL A 721
 None
 1.12A 2a1nA-4czwA:
undetectable		 2a1nA-4czwA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1N_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		5 / 9 THR A 593
LEU A 508
VAL A 511
THR A 515
VAL A 721
 None
 1.07A 2a1nB-4czwA:
0.0		 2a1nB-4czwA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		4 / 6 THR A 593
LEU A 508
VAL A 511
VAL A 721
 None
 0.79A 2feuA-4czwA:
undetectable		 2feuA-4czwA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_B_CAMB1421_0
(CYTOCHROME P450-CAM)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		4 / 7 THR A 593
LEU A 508
VAL A 511
VAL A 721
 None
 0.77A 2feuB-4czwA:
undetectable		 2feuB-4czwA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_D_CHDD702_0
(FERROCHELATASE)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		3 / 3 ARG A1019
GLY A 552
PRO A 553
 None
 0.69A 2hreD-4czwA:
undetectable		 2hreD-4czwA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KUH_A_HLTA150_1
(CALMODULIN)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		4 / 6 LEU A 518
LEU A 596
MET A 512
MET A 846
 None
 1.29A 2kuhA-4czwA:
undetectable		 2kuhA-4czwA:
7.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X91_A_LPRA1615_2
(ANGIOTENSIN
CONVERTING ENZYME)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		3 / 3 SER A1039
THR A1025
PHE A1076
 None
 0.71A 2x91A-4czwA:
undetectable		 2x91A-4czwA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z97_A_CAMA422_0
(CYTOCHROME P450-CAM)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		4 / 6 THR A 593
LEU A 508
VAL A 511
VAL A 721
 None
 0.69A 2z97A-4czwA:
undetectable		 2z97A-4czwA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_B_2FAB500_2
(ADENOSYLHOMOCYSTEINA
SE)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		4 / 5 LEU A 531
THR A 986
THR A 528
HIS A 525
 None
None
None
ZN  A3094 (-3.1A)
 1.17A 2zj0B-4czwA:
undetectable		 2zj0B-4czwA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_C_2FAC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		4 / 5 LEU A 531
THR A 986
THR A 528
HIS A 525
 None
None
None
ZN  A3094 (-3.1A)
 1.26A 2zj0C-4czwA:
undetectable		 2zj0C-4czwA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUH_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		4 / 6 THR A 593
LEU A 508
VAL A 511
VAL A 721
 None
 0.73A 2zuhA-4czwA:
undetectable		 2zuhA-4czwA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUI_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		4 / 6 THR A 593
LEU A 508
VAL A 511
VAL A 721
 None
 0.77A 2zuiA-4czwA:
undetectable		 2zuiA-4czwA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWT_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		4 / 7 THR A 593
LEU A 508
VAL A 511
VAL A 721
 None
 0.78A 2zwtA-4czwA:
undetectable		 2zwtA-4czwA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWU_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		4 / 7 THR A 593
LEU A 508
VAL A 511
VAL A 721
 None
 0.77A 2zwuA-4czwA:
undetectable		 2zwuA-4czwA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_B_ADNB500_2
(ADENOSYLHOMOCYSTEINA
SE)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		4 / 5 LEU A 531
THR A 986
THR A 528
HIS A 525
 None
None
None
ZN  A3094 (-3.1A)
 1.22A 3ce6B-4czwA:
undetectable		 3ce6B-4czwA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		4 / 6 HIS A 513
ALA A 806
GLY A 804
TYR A 514
 None
 0.94A 3dd1A-4czwA:
undetectable		 3dd1A-4czwA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		4 / 7 THR A 593
LEU A 508
VAL A 511
VAL A 721
 None
 0.80A 3fwfA-4czwA:
undetectable		 3fwfA-4czwA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		4 / 7 THR A 593
LEU A 508
VAL A 511
VAL A 721
 None
 0.82A 3fwfB-4czwA:
undetectable		 3fwfB-4czwA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWI_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		4 / 7 THR A 593
LEU A 508
VAL A 511
THR A 515
 None
 0.99A 3fwiA-4czwA:
undetectable		 3fwiA-4czwA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWI_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		4 / 7 THR A 593
LEU A 508
VAL A 511
VAL A 721
 None
 0.78A 3fwiA-4czwA:
undetectable		 3fwiA-4czwA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWJ_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		4 / 7 THR A 593
LEU A 508
VAL A 511
VAL A 721
 None
 0.79A 3fwjA-4czwA:
undetectable		 3fwjA-4czwA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_D_MTXD164_2
(DIHYDROFOLATE
REDUCTASE)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		3 / 3 ARG A 871
ILE A 947
THR A 895
 None
 0.72A 3ia4D-4czwA:
undetectable		 3ia4D-4czwA:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L63_A_CAMA440_0
(CAMPHOR
5-MONOOXYGENASE)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		4 / 7 THR A 593
LEU A 508
VAL A 511
VAL A 721
 None
 0.81A 3l63A-4czwA:
undetectable		 3l63A-4czwA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB323_0
(INVASIN IPAD)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		4 / 7 LEU A1089
ILE A1052
LEU A1040
SER A1039
 None
 0.67A 3r9vA-4czwA:
undetectable
3r9vB-4czwA:
undetectable		 3r9vA-4czwA:
19.50
3r9vB-4czwA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB501_1
(HEMOLYTIC LECTIN
CEL-III)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		4 / 5 ASP A1009
SER A1007
GLY A1005
ASP A 900
 None
 1.41A 3w9tB-4czwA:
undetectable		 3w9tB-4czwA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1003_1
(HEMOLYTIC LECTIN
CEL-III)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		4 / 5 ASP A1009
SER A1007
GLY A1005
ASP A 900
 None
 1.41A 3w9tC-4czwA:
undetectable		 3w9tC-4czwA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD501_1
(HEMOLYTIC LECTIN
CEL-III)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		4 / 5 ASP A1009
SER A1007
GLY A1005
ASP A 900
 None
 1.40A 3w9tD-4czwA:
undetectable		 3w9tD-4czwA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		4 / 7 THR A 593
LEU A 508
VAL A 511
VAL A 721
 None
 0.77A 3wrhA-4czwA:
undetectable		 3wrhA-4czwA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		4 / 7 THR A 593
LEU A 508
VAL A 511
VAL A 721
 None
 0.78A 3wrjA-4czwA:
undetectable		 3wrjA-4czwA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		4 / 7 THR A 593
LEU A 508
VAL A 511
VAL A 721
 None
 0.78A 3wrlA-4czwA:
undetectable		 3wrlA-4czwA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		4 / 7 THR A 593
LEU A 508
VAL A 511
VAL A 721
 None
 0.83A 3wrlE-4czwA:
undetectable		 3wrlE-4czwA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		4 / 7 THR A 593
LEU A 508
VAL A 511
VAL A 721
 None
 0.78A 3wrmA-4czwA:
undetectable		 3wrmA-4czwA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_F_CAMF503_0
(CAMPHOR
5-MONOOXYGENASE)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		4 / 7 THR A 593
LEU A 508
VAL A 511
VAL A 721
 None
 0.80A 3wrmF-4czwA:
undetectable		 3wrmF-4czwA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD393_1
(TETX2 PROTEIN)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		4 / 5 ILE A 718
ILE A 747
TYR A 778
GLU A 746
 None
 1.08A 4a99D-4czwA:
undetectable		 4a99D-4czwA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4A_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		4 / 8 THR A 593
LEU A 508
VAL A 511
VAL A 721
 None
 0.71A 4l4aA-4czwA:
undetectable		 4l4aA-4czwA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4G_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		4 / 7 THR A 593
LEU A 508
VAL A 511
VAL A 721
 None
 0.74A 4l4gA-4czwA:
undetectable		 4l4gA-4czwA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUH_A_ACTA610_0
(SERUM ALBUMIN)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		3 / 3 VAL A 982
SER A 983
THR A 986
 None
 0.42A 4luhA-4czwA:
undetectable		 4luhA-4czwA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_2
(ANDROGEN RECEPTOR)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		4 / 6 MET A 560
LEU A 509
MET A 846
VAL A 801
 None
 1.09A 4okbA-4czwA:
undetectable		 4okbA-4czwA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA301_0
(THAUMATIN-1)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		3 / 3 THR A 501
ASN A 502
SER A 503
 None
 0.77A 4tvtA-4czwA:
undetectable		 4tvtA-4czwA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDA_A_DEXA1985_2
(MINERALOCORTICOID
RECEPTOR)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		4 / 6 LEU A 722
LEU A 635
THR A 515
VAL A 781
 None
 0.99A 4udaA-4czwA:
undetectable		 4udaA-4czwA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2O_C_CLQC1079_0
(SAPOSIN-B)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		4 / 5 ARG A 855
MET A 858
GLU A 613
LEU A 614
 None
 1.37A 4v2oA-4czwA:
undetectable
4v2oC-4czwA:
undetectable		 4v2oA-4czwA:
8.59
4v2oC-4czwA:
8.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_J_4LEJ401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		6 / 9 LEU A 634
ALA A 720
LEU A 517
ALA A 852
LEU A 614
LEU A 630
 None
 1.18A 4z91F-4czwA:
undetectable
4z91G-4czwA:
undetectable
4z91H-4czwA:
undetectable
4z91I-4czwA:
undetectable
4z91J-4czwA:
undetectable		 4z91F-4czwA:
20.62
4z91G-4czwA:
20.62
4z91H-4czwA:
20.62
4z91I-4czwA:
20.62
4z91J-4czwA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_G_SAMG301_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		3 / 3 GLU A 497
HIS A 556
ASP A 481
 None
 0.68A 5c0oG-4czwA:
undetectable		 5c0oG-4czwA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMD_C_6UBC1304_1
(ION TRANSPORT
PROTEIN)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		4 / 5 TYR A 665
ILE A 680
LEU A 690
GLY A 689
 None
 0.95A 5kmdC-4czwA:
undetectable
5kmdD-4czwA:
undetectable		 5kmdC-4czwA:
18.43
5kmdD-4czwA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZJ_A_TEPA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		4 / 8 LEU A 518
PHE A 597
MET A 846
LEU A 508
 None
 0.84A 5mzjA-4czwA:
undetectable		 5mzjA-4czwA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_H_ADNH503_2
(ADENOSYLHOMOCYSTEINA
SE)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		4 / 5 THR A 567
GLU A 539
HIS A 513
LEU A 509
 None
 1.18A 5utuH-4czwA:
undetectable		 5utuH-4czwA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WK9_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		4 / 7 THR A 593
LEU A 508
VAL A 511
VAL A 721
 None
 0.74A 5wk9A-4czwA:
undetectable		 5wk9A-4czwA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XU8_A_DX4A701_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 2)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		6 / 8 GLY A 495
LEU A 496
ASN A 506
GLN A 510
ALA A 799
PHE A 819
 None
 0.32A 5xu8A-4czwA:
20.9		 5xu8A-4czwA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XU8_A_DX4A701_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 2)		 4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
(Neurospora
crassa) 		5 / 8 LEU A 496
SER A 507
GLN A 510
ALA A 799
PHE A 819
 None
 0.69A 5xu8A-4czwA:
20.9		 5xu8A-4czwA:
21.07