SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4d0n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_C_DESC500_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 4d0n A-KINASE ANCHOR
PROTEIN 13
(Homo
sapiens) 		5 / 12 LEU B2141
LEU B2149
CYH B2146
LEU B2148
ILE B2019
 None
 1.04A 1s9pC-4d0nB:
undetectable		 1s9pC-4d0nB:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 4d0n A-KINASE ANCHOR
PROTEIN 13
(Homo
sapiens) 		3 / 3 THR B2210
ASP B2239
SER B2241
 None
 0.84A 2nxeA-4d0nB:
undetectable		 2nxeA-4d0nB:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR4_X_PNTX101_0
(PROTEIN S100-B)		 4d0n A-KINASE ANCHOR
PROTEIN 13
(Homo
sapiens) 		3 / 3 CYH B2105
HIS B2108
PHE B2104
 None
 1.05A 3cr4X-4d0nB:
1.1		 3cr4X-4d0nB:
13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_C_ROFC903_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 4d0n A-KINASE ANCHOR
PROTEIN 13
(Homo
sapiens) 		3 / 3 SER B2054
GLN B2058
PHE B2057
 None
 0.82A 3g4lC-4d0nB:
undetectable		 3g4lC-4d0nB:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_A_RITA600_2
(CYTOCHROME P450 3A4)		 4d0n A-KINASE ANCHOR
PROTEIN 13
(Homo
sapiens) 		4 / 7 PHE B2226
LEU B2236
THR B2212
THR B2335
 None
 1.24A 3nxuA-4d0nB:
undetectable		 3nxuA-4d0nB:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_C_ACHC323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 4d0n A-KINASE ANCHOR
PROTEIN 13
(Homo
sapiens) 		4 / 8 TYR B2157
GLU B2010
TYR B2101
LEU B2097
 None
 1.12A 3rqwC-4d0nB:
2.4
3rqwD-4d0nB:
2.4		 3rqwC-4d0nB:
21.46
3rqwD-4d0nB:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_J_ACHJ323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 4d0n A-KINASE ANCHOR
PROTEIN 13
(Homo
sapiens) 		4 / 8 GLU B2010
TYR B2101
LEU B2097
TYR B2157
 None
 1.13A 3rqwF-4d0nB:
2.8
3rqwJ-4d0nB:
undetectable		 3rqwF-4d0nB:
21.46
3rqwJ-4d0nB:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4d0n A-KINASE ANCHOR
PROTEIN 13
(Homo
sapiens) 		4 / 6 GLN B2008
PHE B2011
PHE B2057
LEU B2061
 None
 0.84A 5z84P-4d0nB:
2.4
5z84W-4d0nB:
undetectable		 5z84P-4d0nB:
18.96
5z84W-4d0nB:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4d0n A-KINASE ANCHOR
PROTEIN 13
(Homo
sapiens) 		4 / 6 GLN B2008
PHE B2011
PHE B2057
LEU B2061
 None
 0.84A 5z85P-4d0nB:
2.4
5z85W-4d0nB:
undetectable		 5z85P-4d0nB:
18.96
5z85W-4d0nB:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4d0n A-KINASE ANCHOR
PROTEIN 13
(Homo
sapiens) 		4 / 6 GLN B2008
PHE B2011
PHE B2057
LEU B2061
 None
 0.86A 5z86P-4d0nB:
2.4
5z86W-4d0nB:
undetectable		 5z86P-4d0nB:
18.96
5z86W-4d0nB:
11.00