SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4d0y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_2_BO221405_1
(PROTEASOME COMPONENT
PRE3)		 4d0y DACB
(Streptococcus
pneumoniae) 		5 / 11 THR A 155
ALA A  76
GLY A 118
ALA A 158
SER A 121
 None
 1.18A 2f162-4d0yA:
undetectable		 2f162-4d0yA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 4d0y DACB
(Streptococcus
pneumoniae) 		5 / 11 THR A 155
ALA A  76
GLY A 118
ALA A 158
SER A 121
 None
 1.19A 2f16N-4d0yA:
undetectable		 2f16N-4d0yA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 4d0y DACB
(Streptococcus
pneumoniae) 		5 / 12 TYR A 229
GLY A 186
GLY A 212
ALA A  94
ILE A 218
 None
 1.11A 3jayA-4d0yA:
undetectable		 3jayA-4d0yA:
11.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_A_HAEA272_1
(COLLAGENASE 3)		 4d0y DACB
(Streptococcus
pneumoniae) 		4 / 5 LEU A 168
HIS A 207
GLU A 204
HIS A 153
 None
ZN  A1239 ( 3.2A)
PO4  A1244 (-1.5A)
ZN  A1239 ( 3.2A)
 0.95A 3kecA-4d0yA:
undetectable		 3kecA-4d0yA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_D_SAMD300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 4d0y DACB
(Streptococcus
pneumoniae) 		5 / 12 GLU A 152
ALA A  76
SER A  65
ASP A  62
LEU A  82
 None
None
None
ZN  A1241 ( 2.4A)
None
 1.45A 3ou6D-4d0yA:
undetectable		 3ou6D-4d0yA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_C_C2FC1410_0
(GLYCINE
N-METHYLTRANSFERASE)		 4d0y DACB
(Streptococcus
pneumoniae) 		3 / 3 ARG A 209
PRO A  92
PHE A 159
 None
 1.04A 3thrC-4d0yA:
undetectable		 3thrC-4d0yA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UGR_A_IMNA2001_2
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 4d0y DACB
(Streptococcus
pneumoniae) 		4 / 7 TYR A 191
TYR A  64
PRO A  88
TYR A  86
 None
 1.23A 3ugrA-4d0yA:
undetectable		 3ugrA-4d0yA:
20.43