SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4d1d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVT_A_FLPA125_1
(TRANSTHYRETIN)		 4d1d HYDANTOIN TRANSPORT
PROTEIN
(Microbacterium
liquefaciens) 		4 / 8 ALA A 316
LEU A 366
LEU A 113
SER A 114
 None
 0.97A 1dvtA-4d1dA:
undetectable
1dvtB-4d1dA:
undetectable		 1dvtA-4d1dA:
14.08
1dvtB-4d1dA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_A_DVAA8_0
(GRAMICIDIN A)		 4d1d HYDANTOIN TRANSPORT
PROTEIN
(Microbacterium
liquefaciens) 		4 / 4 GLY A 279
VAL A 276
TRP A 281
GLY A  50
 None
 0.96A 1ng8A-4d1dA:
undetectable		 1ng8A-4d1dA:
5.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_B_DVAB8_0
(GRAMICIDIN A)		 4d1d HYDANTOIN TRANSPORT
PROTEIN
(Microbacterium
liquefaciens) 		4 / 4 GLY A 279
VAL A 276
TRP A 281
GLY A  50
 None
 0.96A 1ng8B-4d1dA:
undetectable		 1ng8B-4d1dA:
5.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJ6_A_AZMA400_1
(CARBONIC ANHYDRASE
XIV)		 4d1d HYDANTOIN TRANSPORT
PROTEIN
(Microbacterium
liquefaciens) 		5 / 10 HIS A 228
VAL A 231
LEU A  32
LEU A  76
THR A  79
 None
 1.39A 1rj6A-4d1dA:
undetectable		 1rj6A-4d1dA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJ6_B_AZMB401_1
(CARBONIC ANHYDRASE
XIV)		 4d1d HYDANTOIN TRANSPORT
PROTEIN
(Microbacterium
liquefaciens) 		5 / 10 HIS A 228
VAL A 231
LEU A  32
LEU A  76
THR A  79
 None
 1.40A 1rj6B-4d1dA:
undetectable		 1rj6B-4d1dA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DCF_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 4d1d HYDANTOIN TRANSPORT
PROTEIN
(Microbacterium
liquefaciens) 		4 / 6 ALA A  49
TRP A 281
ILE A  47
ILE A  45
 None
 1.10A 2dcfA-4d1dA:
undetectable		 2dcfA-4d1dA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_RALB600_1
(ESTROGEN RECEPTOR)		 4d1d HYDANTOIN TRANSPORT
PROTEIN
(Microbacterium
liquefaciens) 		5 / 12 MET A 214
ALA A 367
LEU A 366
LEU A 370
GLY A 433
 None
 1.09A 2jfaB-4d1dA:
undetectable		 2jfaB-4d1dA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA507_0
(CHORISMATE SYNTHASE)		 4d1d HYDANTOIN TRANSPORT
PROTEIN
(Microbacterium
liquefaciens) 		3 / 3 LEU A 466
ASN A 462
ARG A  85
 None
 0.89A 2qhfA-4d1dA:
undetectable		 2qhfA-4d1dA:
24.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B7P_A_SPMA501_1
(SPERMIDINE SYNTHASE)		 4d1d HYDANTOIN TRANSPORT
PROTEIN
(Microbacterium
liquefaciens) 		5 / 12 GLN A 245
TYR A 381
ASP A 249
GLU A 459
ILE A 389
 None
 1.47A 3b7pA-4d1dA:
undetectable		 3b7pA-4d1dA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B7P_B_SPMB502_1
(SPERMIDINE SYNTHASE)		 4d1d HYDANTOIN TRANSPORT
PROTEIN
(Microbacterium
liquefaciens) 		5 / 12 GLN A 245
TYR A 381
ASP A 249
GLU A 459
ILE A 389
 None
 1.42A 3b7pB-4d1dA:
undetectable		 3b7pB-4d1dA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL4_A_ROCA100_2
(PROTEASE)		 4d1d HYDANTOIN TRANSPORT
PROTEIN
(Microbacterium
liquefaciens) 		5 / 9 ALA A  94
ILE A 100
GLY A 102
ILE A 105
THR A 325
 None
 1.02A 3el4B-4d1dA:
undetectable		 3el4B-4d1dA:
10.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL5_B_1UNB201_1
(PROTEASE)		 4d1d HYDANTOIN TRANSPORT
PROTEIN
(Microbacterium
liquefaciens) 		5 / 10 ALA A  94
ILE A 100
GLY A 102
ILE A 105
THR A 325
 None
 1.02A 3el5A-4d1dA:
undetectable		 3el5A-4d1dA:
10.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GYQ_A_SAMA270_0
(RRNA
(ADENOSINE-2'-O-)-ME
THYLTRANSFERASE)		 4d1d HYDANTOIN TRANSPORT
PROTEIN
(Microbacterium
liquefaciens) 		5 / 12 LEU A 394
ILE A 100
SER A  11
LEU A  12
ARG A 332
 None
 1.14A 3gyqA-4d1dA:
undetectable
3gyqB-4d1dA:
undetectable		 3gyqA-4d1dA:
20.70
3gyqB-4d1dA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJO_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE P)		 4d1d HYDANTOIN TRANSPORT
PROTEIN
(Microbacterium
liquefaciens) 		4 / 8 PHE A 269
VAL A  58
ILE A 287
GLY A 271
 None
 0.95A 3hjoA-4d1dA:
undetectable		 3hjoA-4d1dA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MB5_A_SAMA301_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 4d1d HYDANTOIN TRANSPORT
PROTEIN
(Microbacterium
liquefaciens) 		5 / 12 ILE A 376
GLY A 371
ALA A 437
LEU A 438
ILE A  71
 None
 0.88A 3mb5A-4d1dA:
undetectable		 3mb5A-4d1dA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_A_ACHA301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 4d1d HYDANTOIN TRANSPORT
PROTEIN
(Microbacterium
liquefaciens) 		4 / 7 TYR A 395
THR A  20
TYR A 465
ARG A  25
 None
 1.40A 3wipA-4d1dA:
undetectable
3wipB-4d1dA:
undetectable		 3wipA-4d1dA:
18.09
3wipB-4d1dA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_C_ACHC301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 4d1d HYDANTOIN TRANSPORT
PROTEIN
(Microbacterium
liquefaciens) 		4 / 8 TYR A 395
THR A  20
TYR A 465
ARG A  25
 None
 1.42A 3wipC-4d1dA:
undetectable
3wipD-4d1dA:
undetectable		 3wipC-4d1dA:
18.09
3wipD-4d1dA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_F_ACHF301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 4d1d HYDANTOIN TRANSPORT
PROTEIN
(Microbacterium
liquefaciens) 		4 / 7 TYR A 395
THR A  20
TYR A 465
ARG A  25
 None
 1.40A 3wipF-4d1dA:
undetectable
3wipG-4d1dA:
undetectable		 3wipF-4d1dA:
18.09
3wipG-4d1dA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 4d1d HYDANTOIN TRANSPORT
PROTEIN
(Microbacterium
liquefaciens) 		5 / 12 ILE A 107
ASN A 408
TYR A 403
MET A 377
LEU A 373
 None
 1.30A 4a84A-4d1dA:
undetectable		 4a84A-4d1dA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4d1d HYDANTOIN TRANSPORT
PROTEIN
(Microbacterium
liquefaciens) 		5 / 11 THR A 108
ALA A 111
LEU A 115
PHE A 330
VAL A 333
 None
 1.40A 4claA-4d1dA:
undetectable		 4claA-4d1dA:
15.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IB4_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 4d1d HYDANTOIN TRANSPORT
PROTEIN
(Microbacterium
liquefaciens) 		5 / 12 MET A 182
ALA A 286
TRP A 281
PHE A  46
VAL A  43
 None
 1.11A 4ib4A-4d1dA:
1.6		 4ib4A-4d1dA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NC3_A_ERMA1202_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 4d1d HYDANTOIN TRANSPORT
PROTEIN
(Microbacterium
liquefaciens) 		5 / 12 MET A 182
ALA A 286
TRP A 281
PHE A  46
VAL A  43
 None
 1.10A 4nc3A-4d1dA:
undetectable		 4nc3A-4d1dA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_A_TPVA500_1
(PROTEASE)		 4d1d HYDANTOIN TRANSPORT
PROTEIN
(Microbacterium
liquefaciens) 		5 / 12 ALA A  94
ILE A 100
GLY A 102
ILE A 105
THR A 325
 None
 1.00A 4njuA-4d1dA:
undetectable		 4njuA-4d1dA:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_C_TPVC500_1
(PROTEASE)		 4d1d HYDANTOIN TRANSPORT
PROTEIN
(Microbacterium
liquefaciens) 		5 / 12 ALA A  94
ILE A 100
GLY A 102
ILE A 105
THR A 325
 None
 1.01A 4njuC-4d1dA:
undetectable		 4njuC-4d1dA:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8Y_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 4d1d HYDANTOIN TRANSPORT
PROTEIN
(Microbacterium
liquefaciens) 		6 / 12 GLY A 271
SER A 274
ASN A 282
ILE A  47
ALA A  48
PHE A 216
 None
None
None
None
5ND  A1468 ( 3.4A)
5ND  A1468 ( 4.4A)
 1.47A 4u8yB-4d1dA:
1.8		 4u8yB-4d1dA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V32_A_EF2A151_1
(CEREBLON ISOFORM 4)		 4d1d HYDANTOIN TRANSPORT
PROTEIN
(Microbacterium
liquefaciens) 		4 / 7 ASN A 282
PRO A 283
PHE A  46
PHE A 120
 None
 1.04A 4v32A-4d1dA:
undetectable		 4v32A-4d1dA:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V32_B_EF2B151_1
(CEREBLON ISOFORM 4)		 4d1d HYDANTOIN TRANSPORT
PROTEIN
(Microbacterium
liquefaciens) 		4 / 7 ASN A 282
PRO A 283
PHE A  46
PHE A 120
 None
 1.06A 4v32B-4d1dA:
undetectable		 4v32B-4d1dA:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V32_C_EF2C151_1
(CEREBLON ISOFORM 4)		 4d1d HYDANTOIN TRANSPORT
PROTEIN
(Microbacterium
liquefaciens) 		4 / 7 ASN A 282
PRO A 283
PHE A  46
PHE A 120
 None
 1.38A 4v32C-4d1dA:
undetectable		 4v32C-4d1dA:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC0_A_RITA602_1
(CYTOCHROME P450 3A4)		 4d1d HYDANTOIN TRANSPORT
PROTEIN
(Microbacterium
liquefaciens) 		5 / 12 LEU A 301
PHE A 149
ALA A 177
ILE A  41
ALA A  38
 None
None
None
None
NA  A1471 (-4.9A)
 1.09A 5vc0A-4d1dA:
undetectable		 5vc0A-4d1dA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_1
(ADENOSINE DEAMINASE)		 4d1d HYDANTOIN TRANSPORT
PROTEIN
(Microbacterium
liquefaciens) 		4 / 4 HIS A 228
LEU A 370
TYR A 415
GLY A 375
 None
 1.22A 6n91A-4d1dA:
undetectable		 6n91A-4d1dA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_1
(ADENOSINE DEAMINASE)		 4d1d HYDANTOIN TRANSPORT
PROTEIN
(Microbacterium
liquefaciens) 		4 / 4 HIS A 228
LEU A 370
TYR A 415
GLY A 375
 None
 1.21A 6n91B-4d1dA:
undetectable		 6n91B-4d1dA:
11.78