SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4d1i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB8_0
(GRAMICIDIN A)		 4d1i BETA-GALACTOSIDASE,
PUTATIVE, BGL35A
(Cellvibrio
japonicus) 		3 / 3 VAL A 202
VAL A 206
TRP A 129
 None
 0.75A 1bdwA-4d1iA:
undetectable
1bdwB-4d1iA:
undetectable		 1bdwA-4d1iA:
4.55
1bdwB-4d1iA:
4.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EII_A_RTLA135_0
(CELLULAR
RETINOL-BINDING
PROTEIN II)		 4d1i BETA-GALACTOSIDASE,
PUTATIVE, BGL35A
(Cellvibrio
japonicus) 		5 / 12 ALA A  37
ILE A  60
THR A  89
LEU A 125
LEU A 276
 None
 1.29A 1eiiA-4d1iA:
undetectable		 1eiiA-4d1iA:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_A_CFXA1300_2
(BETA-LACTAMASE)		 4d1i BETA-GALACTOSIDASE,
PUTATIVE, BGL35A
(Cellvibrio
japonicus) 		4 / 5 PRO A  72
LEU A  75
THR A 196
ARG A 119
 None
 1.34A 1i2wA-4d1iA:
undetectable		 1i2wA-4d1iA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_D_DEXD4999_2
(GLUCOCORTICOID
RECEPTOR)		 4d1i BETA-GALACTOSIDASE,
PUTATIVE, BGL35A
(Cellvibrio
japonicus) 		4 / 5 LEU A 127
TRP A  79
LEU A 115
GLN A  98
 None
 1.49A 1p93D-4d1iA:
undetectable		 1p93D-4d1iA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_A_ZMRA1477_2
(NEURAMINIDASE)		 4d1i BETA-GALACTOSIDASE,
PUTATIVE, BGL35A
(Cellvibrio
japonicus) 		4 / 5 LEU A 115
ARG A 124
ARG A 119
ILE A 198
 None
 1.21A 2cmlA-4d1iA:
undetectable		 2cmlA-4d1iA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_B_ZMRB2477_2
(NEURAMINIDASE)		 4d1i BETA-GALACTOSIDASE,
PUTATIVE, BGL35A
(Cellvibrio
japonicus) 		4 / 5 LEU A 115
ARG A 124
ARG A 119
ILE A 198
 None
 1.19A 2cmlB-4d1iA:
undetectable		 2cmlB-4d1iA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_C_ZMRC3477_2
(NEURAMINIDASE)		 4d1i BETA-GALACTOSIDASE,
PUTATIVE, BGL35A
(Cellvibrio
japonicus) 		4 / 5 LEU A 115
ARG A 124
ARG A 119
ILE A 198
 None
 1.21A 2cmlC-4d1iA:
undetectable		 2cmlC-4d1iA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_D_ZMRD4477_2
(NEURAMINIDASE)		 4d1i BETA-GALACTOSIDASE,
PUTATIVE, BGL35A
(Cellvibrio
japonicus) 		4 / 5 LEU A 115
ARG A 124
ARG A 119
ILE A 198
 None
 1.18A 2cmlD-4d1iA:
undetectable		 2cmlD-4d1iA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_A_BEZA352_0
(D-AMINO-ACID OXIDASE)		 4d1i BETA-GALACTOSIDASE,
PUTATIVE, BGL35A
(Cellvibrio
japonicus) 		4 / 6 LEU A  51
TYR A  58
ILE A 198
GLY A  62
 None
 0.87A 2du8A-4d1iA:
undetectable		 2du8A-4d1iA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_B_BEZB1352_0
(D-AMINO-ACID OXIDASE)		 4d1i BETA-GALACTOSIDASE,
PUTATIVE, BGL35A
(Cellvibrio
japonicus) 		4 / 6 LEU A  51
TYR A  58
ILE A 198
GLY A  62
 None
 0.91A 2du8B-4d1iA:
undetectable		 2du8B-4d1iA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_D_SAMD300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 4d1i BETA-GALACTOSIDASE,
PUTATIVE, BGL35A
(Cellvibrio
japonicus) 		4 / 4 SER A 297
TRP A 133
ASP A 317
ILE A 316
 None
 1.47A 2oxtD-4d1iA:
undetectable		 2oxtD-4d1iA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4d1i BETA-GALACTOSIDASE,
PUTATIVE, BGL35A
(Cellvibrio
japonicus) 		5 / 12 PHE A 374
ASN A 135
VAL A 282
ASN A 281
TYR A 279
 None
 1.30A 2y01A-4d1iA:
undetectable		 2y01A-4d1iA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGO_A_PCFA1213_1
(WNT INHIBITORY
FACTOR 1)		 4d1i BETA-GALACTOSIDASE,
PUTATIVE, BGL35A
(Cellvibrio
japonicus) 		4 / 6 LEU A 318
ILE A 319
PRO A 321
VAL A 111
 None
 1.02A 2ygoA-4d1iA:
undetectable		 2ygoA-4d1iA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DAU_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 4d1i BETA-GALACTOSIDASE,
PUTATIVE, BGL35A
(Cellvibrio
japonicus) 		5 / 12 ALA A 348
ASP A 322
LEU A 284
ALA A 283
LEU A 306
 None
 1.13A 3dauA-4d1iA:
undetectable		 3dauA-4d1iA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4d1i BETA-GALACTOSIDASE,
PUTATIVE, BGL35A
(Cellvibrio
japonicus) 		5 / 10 GLY A 493
ILE A 496
VAL A 513
VAL A 472
GLN A 461
 None
 1.38A 3fhjC-4d1iA:
undetectable		 3fhjC-4d1iA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4d1i BETA-GALACTOSIDASE,
PUTATIVE, BGL35A
(Cellvibrio
japonicus) 		5 / 9 GLY A 493
ILE A 496
VAL A 513
VAL A 472
GLN A 461
 None
 1.39A 3fhjD-4d1iA:
undetectable		 3fhjD-4d1iA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4d1i BETA-GALACTOSIDASE,
PUTATIVE, BGL35A
(Cellvibrio
japonicus) 		5 / 10 GLY A 493
ILE A 496
VAL A 513
VAL A 472
GLN A 461
 None
 1.38A 3fhjE-4d1iA:
undetectable		 3fhjE-4d1iA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4d1i BETA-GALACTOSIDASE,
PUTATIVE, BGL35A
(Cellvibrio
japonicus) 		5 / 9 GLY A 493
ILE A 496
VAL A 513
VAL A 472
GLN A 461
 None
 1.39A 3fhjF-4d1iA:
undetectable		 3fhjF-4d1iA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_K_TRPK1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4d1i BETA-GALACTOSIDASE,
PUTATIVE, BGL35A
(Cellvibrio
japonicus) 		5 / 9 GLY A 493
ILE A 496
VAL A 513
VAL A 472
GLN A 461
 None
 1.41A 3fi0K-4d1iA:
undetectable		 3fi0K-4d1iA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_A_486A3_1
(GLUCOCORTICOID
RECEPTOR)		 4d1i BETA-GALACTOSIDASE,
PUTATIVE, BGL35A
(Cellvibrio
japonicus) 		5 / 12 LEU A 306
GLY A 301
VAL A 206
LEU A 318
ILE A 316
 None
 1.24A 3h52A-4d1iA:
undetectable		 3h52A-4d1iA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB1_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 4d1i BETA-GALACTOSIDASE,
PUTATIVE, BGL35A
(Cellvibrio
japonicus) 		5 / 12 GLY A 207
ALA A 137
ALA A 211
ALA A 283
PRO A 293
 None
 1.08A 3jb1A-4d1iA:
undetectable		 3jb1A-4d1iA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RZE_A_D7VA1201_1
(HISTAMINE H1
RECEPTOR, LYSOZYME
CHIMERA)		 4d1i BETA-GALACTOSIDASE,
PUTATIVE, BGL35A
(Cellvibrio
japonicus) 		5 / 12 THR A 395
ILE A 396
ASN A 352
PHE A 371
TYR A 509
 None
 1.35A 3rzeA-4d1iA:
undetectable		 3rzeA-4d1iA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_A_ZMRA1002_2
(NEURAMINIDASE)		 4d1i BETA-GALACTOSIDASE,
PUTATIVE, BGL35A
(Cellvibrio
japonicus) 		4 / 5 LEU A 115
ARG A 124
ARG A 119
ILE A 198
 None
 1.22A 3ticA-4d1iA:
undetectable		 3ticA-4d1iA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_D_ZMRD1002_2
(NEURAMINIDASE)		 4d1i BETA-GALACTOSIDASE,
PUTATIVE, BGL35A
(Cellvibrio
japonicus) 		4 / 5 LEU A 115
ARG A 124
ARG A 119
ILE A 198
 None
 1.23A 3ticD-4d1iA:
undetectable		 3ticD-4d1iA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX5_B_MIYB1103_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 4d1i BETA-GALACTOSIDASE,
PUTATIVE, BGL35A
(Cellvibrio
japonicus) 		5 / 12 SER A  91
GLY A 351
ASP A 322
ILE A 323
VAL A 331
 None
 1.18A 4dx5B-4d1iA:
undetectable		 4dx5B-4d1iA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_B_ECNB403_1
(FLAVOHEMOGLOBIN)		 4d1i BETA-GALACTOSIDASE,
PUTATIVE, BGL35A
(Cellvibrio
japonicus) 		5 / 11 ILE A  59
PHE A 371
ALA A  87
LEU A  61
LEU A 360
 None
 1.11A 4g1bB-4d1iA:
undetectable		 4g1bB-4d1iA:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_D_LOCD502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 4d1i BETA-GALACTOSIDASE,
PUTATIVE, BGL35A
(Cellvibrio
japonicus) 		4 / 4 ASN A 281
SER A  91
ALA A 348
VAL A 347
 None
 1.28A 4x1kC-4d1iA:
undetectable		 4x1kC-4d1iA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_F_MFXF2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 4d1i BETA-GALACTOSIDASE,
PUTATIVE, BGL35A
(Cellvibrio
japonicus) 		4 / 6 ARG A 340
ASP A 303
ARG A 285
GLY A 301
 None
 0.87A 5cdqA-4d1iA:
undetectable
5cdqC-4d1iA:
undetectable
5cdqD-4d1iA:
2.1		 5cdqA-4d1iA:
21.47
5cdqC-4d1iA:
21.47
5cdqD-4d1iA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_B_C2FB402_1
(THYMIDYLATE SYNTHASE)		 4d1i BETA-GALACTOSIDASE,
PUTATIVE, BGL35A
(Cellvibrio
japonicus) 		3 / 3 ASN A 392
ASP A 353
GLY A 387
 None
 0.61A 5fctB-4d1iA:
undetectable		 5fctB-4d1iA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_B_SAMB301_0
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 4d1i BETA-GALACTOSIDASE,
PUTATIVE, BGL35A
(Cellvibrio
japonicus) 		5 / 12 ALA A 511
GLY A 475
ALA A 508
LEU A 405
GLY A 492
 None
 1.25A 5jglB-4d1iA:
2.4		 5jglB-4d1iA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5P9I_A_1E8A701_2
(TYROSINE-PROTEIN
KINASE BTK)		 4d1i BETA-GALACTOSIDASE,
PUTATIVE, BGL35A
(Cellvibrio
japonicus) 		4 / 5 LEU A 128
TYR A 279
MET A 278
ASP A 177
 None
 1.44A 5p9iA-4d1iA:
undetectable		 5p9iA-4d1iA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYE_B_TA1B502_1
(TUBULIN BETA CHAIN)		 4d1i BETA-GALACTOSIDASE,
PUTATIVE, BGL35A
(Cellvibrio
japonicus) 		5 / 12 GLU A 397
LEU A 495
ALA A 357
PRO A 373
GLY A  62
 None
 1.00A 5syeB-4d1iA:
undetectable		 5syeB-4d1iA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA902_1
(MRNA CAPPING ENZYME
P5)		 4d1i BETA-GALACTOSIDASE,
PUTATIVE, BGL35A
(Cellvibrio
japonicus) 		3 / 3 TYR A 187
ASP A 107
ASP A 112
 None
 0.70A 5x6yA-4d1iA:
undetectable		 5x6yA-4d1iA:
20.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IFT_A_SAMA301_1
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A)		 4d1i BETA-GALACTOSIDASE,
PUTATIVE, BGL35A
(Cellvibrio
japonicus) 		4 / 5 GLN A 354
ASP A 327
ASN A 352
TYR A 359
 None
 1.45A 6iftA-4d1iA:
2.4		 6iftA-4d1iA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_B_LLLB301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 4d1i BETA-GALACTOSIDASE,
PUTATIVE, BGL35A
(Cellvibrio
japonicus) 		4 / 7 ASP A 230
ARG A 261
TYR A 257
ASP A 264
 None
 1.26A 6mn5B-4d1iA:
undetectable		 6mn5B-4d1iA:
9.94