SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4d28'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_B_9CRB165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 4d28 CBL-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 24
(Arabidopsis
thaliana) 		5 / 12 LYS A  83
VAL A  87
ILE A  39
ILE A  41
LYS A  26
 None
 0.76A 1epbB-4d28A:
undetectable		 1epbB-4d28A:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IEP_B_STIB202_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)		 4d28 CBL-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 24
(Arabidopsis
thaliana) 		4 / 7 LYS A  40
ILE A  86
ARG A 133
LEU A 141
 None
 0.97A 1iepB-4d28A:
12.8		 1iepB-4d28A:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IEP_B_STIB202_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)		 4d28 CBL-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 24
(Arabidopsis
thaliana) 		4 / 7 LYS A  40
VAL A  72
ARG A 133
LEU A 141
 None
 0.91A 1iepB-4d28A:
12.8		 1iepB-4d28A:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_D_SAMD301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4d28 CBL-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 24
(Arabidopsis
thaliana) 		3 / 3 LYS A 259
ASP A 143
ASP A 120
 None
 0.99A 2br4D-4d28A:
undetectable		 2br4D-4d28A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_B_BEZB1352_0
(D-AMINO-ACID OXIDASE)		 4d28 CBL-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 24
(Arabidopsis
thaliana) 		4 / 6 LEU A 218
TYR A 219
ILE A 222
GLY A 171
 None
 0.95A 2du8B-4d28A:
undetectable		 2du8B-4d28A:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CS9_A_NILA600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4d28 CBL-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 24
(Arabidopsis
thaliana) 		6 / 10 VAL A  25
LYS A  40
VAL A  72
ILE A  86
PHE A  90
VAL A 150
 None
 0.78A 3cs9A-4d28A:
20.7		 3cs9A-4d28A:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CS9_B_NILB600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4d28 CBL-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 24
(Arabidopsis
thaliana) 		6 / 9 VAL A  25
LYS A  40
VAL A  72
ILE A  86
LEU A 141
VAL A 150
 None
 0.88A 3cs9B-4d28A:
20.6		 3cs9B-4d28A:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CS9_C_NILC600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4d28 CBL-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 24
(Arabidopsis
thaliana) 		5 / 9 VAL A  25
LYS A  40
VAL A  72
ILE A  86
VAL A 150
 None
 0.59A 3cs9C-4d28A:
20.6		 3cs9C-4d28A:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_D_STID1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 4d28 CBL-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 24
(Arabidopsis
thaliana) 		4 / 6 VAL A  25
LYS A  40
VAL A  72
ILE A  86
 None
 0.57A 3mssD-4d28A:
20.9		 3mssD-4d28A:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_2
(PROTEASE)		 4d28 CBL-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 24
(Arabidopsis
thaliana) 		5 / 11 ASP A 246
ILE A 253
GLY A 197
ILE A 199
ILE A 255
 None
 1.00A 3s53B-4d28A:
undetectable		 3s53B-4d28A:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTR_A_LQZA90_1
(LACTOTRANSFERRIN)		 4d28 CBL-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 24
(Arabidopsis
thaliana) 		3 / 3 PRO A 173
THR A 172
LEU A 208
 None
 0.80A 3ttrA-4d28A:
undetectable		 3ttrA-4d28A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UGR_A_IMNA2001_2
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 4d28 CBL-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 24
(Arabidopsis
thaliana) 		4 / 7 ASN A 248
GLU A 179
GLN A 184
TYR A 186
 None
 1.28A 3ugrA-4d28A:
undetectable		 3ugrA-4d28A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WZD_A_LEVA1201_2
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 4d28 CBL-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 24
(Arabidopsis
thaliana) 		4 / 5 LYS A  40
VAL A  72
LEU A 141
ASP A 152
 None
 0.94A 3wzdA-4d28A:
20.8		 3wzdA-4d28A:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAA_A_RTZA401_1
(SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 4d28 CBL-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 24
(Arabidopsis
thaliana) 		6 / 11 VAL A  25
ALA A  38
LYS A  40
LEU A  88
GLU A 138
LEU A 141
 None
 0.98A 4iaaA-4d28A:
24.2		 4iaaA-4d28A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KS8_A_B49A701_1
(SERINE/THREONINE-PRO
TEIN KINASE PAK 6)		 4d28 CBL-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 24
(Arabidopsis
thaliana) 		7 / 10 ILE A  17
ALA A  38
VAL A  72
PHE A  90
LEU A 141
SER A 151
ASP A 152
 None
 1.36A 4ks8A-4d28A:
22.5		 4ks8A-4d28A:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZ7_A_1E8A901_1
(CGMP-DEPENDENT
PROTEIN KINASE,
PUTATIVE)		 4d28 CBL-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 24
(Arabidopsis
thaliana) 		5 / 10 ILE A  17
ALA A  38
LYS A  40
VAL A  91
LEU A 141
 None
 1.03A 4rz7A-4d28A:
11.7		 4rz7A-4d28A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YNM_A_SAMA2304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
ASH1L)		 4d28 CBL-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 24
(Arabidopsis
thaliana) 		5 / 12 LYS A 128
GLY A 129
HIS A 132
HIS A  68
ILE A  71
 None
 1.28A 4ynmA-4d28A:
undetectable		 4ynmA-4d28A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YPA_C_SAMC2304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
ASH1L)		 4d28 CBL-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 24
(Arabidopsis
thaliana) 		5 / 12 LYS A 128
GLY A 129
HIS A 132
HIS A  68
ILE A  71
 None
 1.30A 4ypaC-4d28A:
undetectable		 4ypaC-4d28A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC3_A_DB8A601_2
(WEE1-LIKE PROTEIN
KINASE)		 4d28 CBL-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 24
(Arabidopsis
thaliana) 		4 / 4 VAL A  25
LYS A  40
VAL A  72
ASN A 139
 None
 0.86A 5vc3A-4d28A:
22.0		 5vc3A-4d28A:
21.96