SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4d3c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H8S_A_AICA1000_1
(MUTANT AL2 6E7P9G)		 4d3c SFN68 FAB
(Oryctolagus
cuniculus) 		6 / 12 TYR L  36
GLN L  89
PHE L  99
VAL H  37
ALA H  97
TRP H 106
 None
 0.84A 1h8sA-4d3cL:
20.7		 1h8sA-4d3cL:
39.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 4d3c SFN68 FAB
SFN68 FAB
(Oryctolagus
cuniculus;
Oryctolagus
cuniculus) 		4 / 7 GLN L  89
GLY H  99
GLY H 101
ALA H  97
 None
 0.84A 3fpjB-4d3cL:
undetectable		 3fpjB-4d3cL:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA302_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 4d3c SFN68 FAB
(Oryctolagus
cuniculus) 		4 / 6 LEU H 192
GLY H 193
ALA H 128
PRO H 129
 None
 0.49A 3huoA-4d3cH:
undetectable		 3huoA-4d3cH:
26.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_C_ADNC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 4d3c SFN68 FAB
(Oryctolagus
cuniculus) 		4 / 5 LEU H 111
GLN H  39
THR H  93
GLU H 151
 None
 1.48A 3n58C-4d3cH:
undetectable		 3n58C-4d3cH:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_2
(ADENOSINE KINASE)		 4d3c SFN68 FAB
(Oryctolagus
cuniculus) 		4 / 5 LEU L   2
SER L  28
LEU L  32
LEU L   4
 None
 1.14A 4n09B-4d3cL:
undetectable		 4n09B-4d3cL:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_2
(ADENOSINE KINASE)		 4d3c SFN68 FAB
(Oryctolagus
cuniculus) 		4 / 5 LEU L   2
SER L  28
LEU L  32
LEU L   4
 None
 1.12A 4n09D-4d3cL:
undetectable		 4n09D-4d3cL:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA409_0
(FAD:PROTEIN FMN
TRANSFERASE)		 4d3c SFN68 FAB
(Oryctolagus
cuniculus) 		4 / 5 VAL L  19
ILE L  21
VAL L 105
THR L 103
 None
 0.72A 4xdtA-4d3cL:
undetectable		 4xdtA-4d3cL:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGP_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 4d3c SFN68 FAB
(Oryctolagus
cuniculus) 		5 / 12 PRO L   8
VAL L 105
ALA L  14
ALA L  13
VAL L  19
 None
 1.12A 5igpA-4d3cL:
undetectable		 5igpA-4d3cL:
19.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MTH_A_ACTA302_0
(ANTIBODY FAB HEAVY
CHAIN)		 4d3c SFN68 FAB
(Oryctolagus
cuniculus) 		4 / 5 SER H 115
ALA H 117
PHE H 149
LEU H 173
 None
 0.30A 5mthA-4d3cH:
27.1		 5mthA-4d3cH:
55.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA CHAIN)		 4d3c SFN68 FAB
(Oryctolagus
cuniculus) 		3 / 3 SER L  12
ALA L  14
VAL L  15
 None
 0.51A 5xiwC-4d3cL:
undetectable		 5xiwC-4d3cL:
16.90