SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4d3r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2KOT_B_ANWB99_0 (PROTEIN S100-A13)	4d3r	DUAL SPECIFICITY PROTEIN PHOSPHATASE 19 (Homo sapiens)	4 / 8	VAL A 92 THR A 93 PHE A 110 THR A 111	None	1.12A	2kotB-4d3rA: undetectable	2kotB-4d3rA: 16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y7K_A_SALA1302_1 (LYSR-TYPE REGULATORY PROTEIN)	4d3r	DUAL SPECIFICITY PROTEIN PHOSPHATASE 19 (Homo sapiens)	5 / 11	ILE A 162 GLY A 163 PHE A 129 PRO A 189 ILE A 125	None	1.29A	2y7kA-4d3rA: undetectable	2y7kA-4d3rA: 19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y7K_B_SALB1304_1 (LYSR-TYPE REGULATORY PROTEIN)	4d3r	DUAL SPECIFICITY PROTEIN PHOSPHATASE 19 (Homo sapiens)	5 / 10	ILE A 162 GLY A 163 PHE A 129 PRO A 189 ILE A 125	None	1.30A	2y7kB-4d3rA: undetectable	2y7kB-4d3rA: 19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AYC_A_1YNA502_2 (PROTEIN CYP51)	4d3r	DUAL SPECIFICITY PROTEIN PHOSPHATASE 19 (Homo sapiens)	4 / 7	VAL A 148 PHE A 177 PHE A 129 LEU A 197	None	1.01A	6aycA-4d3rA: undetectable	6aycA-4d3rA: 18.31

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2KOT_B_ANWB99_0","PROTEIN S100-A13","4d3r","DUAL SPECIFICITY PROTEIN PHOSPHATASE 19","Homo sapiens",4,"VAL A  92;THR A  93;PHE A 110;THR A 111","None","1.12A","2kotB-4d3rA:undetectable","2kotB-4d3rA:16.78"],["2Y7K_A_SALA1302_1","LYSR-TYPE REGULATORY PROTEIN","4d3r","DUAL SPECIFICITY PROTEIN PHOSPHATASE 19","Homo sapiens",5,"ILE A 162;GLY A 163;PHE A 129;PRO A 189;ILE A 125","None","1.29A","2y7kA-4d3rA:undetectable","2y7kA-4d3rA:19.72"],["2Y7K_B_SALB1304_1","LYSR-TYPE REGULATORY PROTEIN","4d3r","DUAL SPECIFICITY PROTEIN PHOSPHATASE 19","Homo sapiens",5,"ILE A 162;GLY A 163;PHE A 129;PRO A 189;ILE A 125","None","1.30A","2y7kB-4d3rA:undetectable","2y7kB-4d3rA:19.72"],["6AYC_A_1YNA502_2","PROTEIN CYP51","4d3r","DUAL SPECIFICITY PROTEIN PHOSPHATASE 19","Homo sapiens",4,"VAL A 148;PHE A 177;PHE A 129;LEU A 197","None","1.01A","6aycA-4d3rA:undetectable","6aycA-4d3rA:18.31"]]