SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4d48'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9G_A_SAMA301_0
(HYPOTHETICAL PROTEIN
RV2118C)		 4d48 GLUCOSE-1-PHOSPHATE
URIDYLYLTRANSFERASE
(Erwinia
amylovora) 		5 / 12 GLY A 280
GLY A 287
SER A 288
ALA A 292
LEU A 294
 None
 1.28A 1i9gA-4d48A:
undetectable		 1i9gA-4d48A:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JTV_A_TESA500_1
(17
BETA-HYDROXYSTEROID
DEHYDROGENASE TYPE 1)		 4d48 GLUCOSE-1-PHOSPHATE
URIDYLYLTRANSFERASE
(Erwinia
amylovora) 		4 / 8 HIS A 264
SER A 263
VAL A 262
GLU A 278
 None
 0.90A 1jtvA-4d48A:
undetectable		 1jtvA-4d48A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OLT_A_SAMA501_0
(OXYGEN-INDEPENDENT
COPROPORPHYRINOGEN
III OXIDASE)		 4d48 GLUCOSE-1-PHOSPHATE
URIDYLYLTRANSFERASE
(Erwinia
amylovora) 		5 / 12 THR A  26
GLY A 267
ASP A 137
ILE A 139
TYR A  44
 None
 1.18A 1oltA-4d48A:
undetectable		 1oltA-4d48A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_2
(TUBULIN ALPHA CHAIN)		 4d48 GLUCOSE-1-PHOSPHATE
URIDYLYLTRANSFERASE
(Erwinia
amylovora) 		4 / 5 VAL A  46
ASN A  47
VAL A 102
ILE A 104
 None
 1.05A 1z2bC-4d48A:
undetectable		 1z2bC-4d48A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_2
(CYTOCHROME P450 2R1)		 4d48 GLUCOSE-1-PHOSPHATE
URIDYLYLTRANSFERASE
(Erwinia
amylovora) 		3 / 3 MET A 155
VAL A 169
GLU A 255
 None
 0.87A 3c6gA-4d48A:
undetectable		 3c6gA-4d48A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC6_C_REAC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4d48 GLUCOSE-1-PHOSPHATE
URIDYLYLTRANSFERASE
(Erwinia
amylovora) 		5 / 12 VAL A  45
CYH A  49
ALA A  51
ALA A  52
LEU A 147
 None
 0.97A 3fc6C-4d48A:
undetectable		 3fc6C-4d48A:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N3I_A_ROCA201_1
(PROTEASE)		 4d48 GLUCOSE-1-PHOSPHATE
URIDYLYLTRANSFERASE
(Erwinia
amylovora) 		5 / 12 GLY A  53
ALA A  52
ILE A  57
VAL A 219
ILE A 134
 None
 1.16A 3n3iA-4d48A:
undetectable		 3n3iA-4d48A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVC_A_HFGA1602_0
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)		 4d48 GLUCOSE-1-PHOSPHATE
URIDYLYLTRANSFERASE
(Erwinia
amylovora) 		5 / 12 VAL A 119
PRO A  14
GLU A  32
THR A  20
GLY A  19
 None
 1.28A 4hvcA-4d48A:
undetectable		 4hvcA-4d48A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLF_A_HFGA802_0
(PROLINE--TRNA LIGASE)		 4d48 GLUCOSE-1-PHOSPHATE
URIDYLYLTRANSFERASE
(Erwinia
amylovora) 		5 / 12 VAL A 119
PRO A  14
GLU A  32
THR A  20
GLY A  19
 None
 1.29A 4olfA-4d48A:
undetectable		 4olfA-4d48A:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_A_ILEA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4d48 GLUCOSE-1-PHOSPHATE
URIDYLYLTRANSFERASE
(Erwinia
amylovora) 		4 / 6 ALA A  16
THR A  61
VAL A  60
HIS A  62
 None
 1.02A 5eclA-4d48A:
undetectable		 5eclA-4d48A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IMS_B_ACTB713_0
(ACETOLACTATE
SYNTHASE CATALYTIC
SUBUNIT,
MITOCHONDRIAL)		 4d48 GLUCOSE-1-PHOSPHATE
URIDYLYLTRANSFERASE
(Erwinia
amylovora) 		3 / 3 GLY A  17
GLN A 109
LYS A  65
 None
 0.93A 5imsB-4d48A:
undetectable		 5imsB-4d48A:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_C_HFGC1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 4d48 GLUCOSE-1-PHOSPHATE
URIDYLYLTRANSFERASE
(Erwinia
amylovora) 		5 / 12 VAL A 119
PRO A  14
GLU A  32
THR A  20
GLY A  19
 None
 1.20A 5xipC-4d48A:
undetectable		 5xipC-4d48A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_A_HFGA1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 4d48 GLUCOSE-1-PHOSPHATE
URIDYLYLTRANSFERASE
(Erwinia
amylovora) 		5 / 12 VAL A 119
PRO A  14
GLU A  32
THR A  20
GLY A  19
 None
 1.27A 5xiqA-4d48A:
undetectable		 5xiqA-4d48A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_D_HFGD1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 4d48 GLUCOSE-1-PHOSPHATE
URIDYLYLTRANSFERASE
(Erwinia
amylovora) 		5 / 12 VAL A 119
PRO A  14
GLU A  32
THR A  20
GLY A  19
 None
 1.26A 5xiqD-4d48A:
2.2		 5xiqD-4d48A:
21.71