SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4d51'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KNY_A_KANA558_1
(KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE)		 4d51 CYMA
(Klebsiella
oxytoca) 		4 / 7 SER A 119
GLU A 164
GLU A 135
GLU A 174
 None
 1.18A 1knyA-4d51A:
undetectable
1knyB-4d51A:
undetectable		 1knyA-4d51A:
19.88
1knyB-4d51A:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_C_H4BC1002_1
(HYPOTHETICAL PROTEIN
PH0634)		 4d51 CYMA
(Klebsiella
oxytoca) 		4 / 6 ASP A   3
THR A  48
GLU A  32
GLU A  74
 None
 1.31A 2dttB-4d51A:
0.9
2dttC-4d51A:
1.0		 2dttB-4d51A:
16.24
2dttC-4d51A:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_C_H4BC1002_1
(HYPOTHETICAL PROTEIN
PH0634)		 4d51 CYMA
(Klebsiella
oxytoca) 		4 / 6 ASP A   3
THR A  50
GLU A  30
GLU A  74
 None
 1.15A 2dttB-4d51A:
0.9
2dttC-4d51A:
1.0		 2dttB-4d51A:
16.24
2dttC-4d51A:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_C_H4BC1002_1
(HYPOTHETICAL PROTEIN
PH0634)		 4d51 CYMA
(Klebsiella
oxytoca) 		4 / 6 ASP A   3
THR A 315
GLU A  30
GLU A 289
 None
 1.39A 2dttB-4d51A:
0.9
2dttC-4d51A:
1.0		 2dttB-4d51A:
16.24
2dttC-4d51A:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6U_A_BEZA501_0
(NIKD PROTEIN)		 4d51 CYMA
(Klebsiella
oxytoca) 		4 / 7 ARG A 240
GLU A 224
TYR A 197
LYS A   8
 None
 1.37A 2q6uA-4d51A:
0.0		 2q6uA-4d51A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 4d51 CYMA
(Klebsiella
oxytoca) 		3 / 3 ASN A 156
ARG A 139
ASP A   3
 None
 0.89A 2qe6A-4d51A:
undetectable		 2qe6A-4d51A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 4d51 CYMA
(Klebsiella
oxytoca) 		3 / 3 ASN A 156
ARG A 139
ASP A   3
 None
 0.95A 2qe6B-4d51A:
undetectable		 2qe6B-4d51A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_D_KLND1499_1
(CYTOCHROME P450 3A4)		 4d51 CYMA
(Klebsiella
oxytoca) 		4 / 5 PHE A 324
PHE A  65
PHE A  56
ILE A 111
 None
 1.36A 2v0mD-4d51A:
undetectable		 2v0mD-4d51A:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_0
(YAEB-LIKE PROTEIN
RPA0152)		 4d51 CYMA
(Klebsiella
oxytoca) 		3 / 3 LYS A 201
ARG A 172
LYS A  91
 None
 1.48A 3okxA-4d51A:
undetectable		 3okxA-4d51A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQF_B_QPSB951_1
(ALPHA-GLUCAN
PHOSPHORYLASE 2,
CYTOSOLIC)		 4d51 CYMA
(Klebsiella
oxytoca) 		4 / 8 GLU A 135
GLU A 164
LYS A 131
ARG A 166
 None
 1.01A 4bqfB-4d51A:
undetectable		 4bqfB-4d51A:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_D_PARD500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 4d51 CYMA
(Klebsiella
oxytoca) 		4 / 8 SER A  95
SER A   2
GLU A 195
TYR A 141
 None
 1.18A 4qb9D-4d51A:
undetectable		 4qb9D-4d51A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_B_SAMB301_1
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 4d51 CYMA
(Klebsiella
oxytoca) 		3 / 3 ASP A   3
GLU A 224
SER A 162
 None
 0.85A 5bw4B-4d51A:
undetectable		 5bw4B-4d51A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DEB_B_MTXB303_1
(BIFUNCTIONAL PROTEIN
FOLD)		 4d51 CYMA
(Klebsiella
oxytoca) 		4 / 5 TYR A 154
LYS A 182
GLY A  67
ILE A 111
 None
 1.39A 6debB-4d51A:
undetectable		 6debB-4d51A:
13.75