SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4d63'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7R_A_NCTA440_1
(CYTOCHROME P450-CAM)		 4d63 FIBER KNOB DOMAIN
(Turkey
siadenovirus
A) 		4 / 7 PHE A 449
THR A 395
VAL A 398
ILE A 396
 None
 0.72A 1p7rA-4d63A:
undetectable		 1p7rA-4d63A:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_E_TFPE201_1
(PROTEIN S100-A4)		 4d63 FIBER KNOB DOMAIN
(Turkey
siadenovirus
A) 		4 / 7 GLY A 387
PHE A 324
PHE A 449
PHE A 347
 None
 1.11A 3ko0D-4d63A:
undetectable
3ko0E-4d63A:
undetectable		 3ko0D-4d63A:
16.95
3ko0E-4d63A:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S43_A_478A401_2
(PROTEASE)		 4d63 FIBER KNOB DOMAIN
(Turkey
siadenovirus
A) 		5 / 10 GLY A 414
ILE A 438
VAL A 434
ILE A 411
ILE A 441
 None
 0.96A 3s43B-4d63A:
undetectable		 3s43B-4d63A:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_2
(PROTEASE)		 4d63 FIBER KNOB DOMAIN
(Turkey
siadenovirus
A) 		5 / 11 LEU A 400
ILE A 365
ILE A 428
ILE A 441
ILE A 443
 None
 1.06A 3s53B-4d63A:
undetectable		 3s53B-4d63A:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_C_DAHC60_1
(PUTATIVE CYTOCHROME
C)		 4d63 FIBER KNOB DOMAIN
(Turkey
siadenovirus
A) 		4 / 6 MET A 427
ASN A 422
VAL A 420
LEU A 418
 None
SIA  A1455 (-4.5A)
SIA  A1455 (-4.4A)
None
 1.14A 5xdhA-4d63A:
undetectable
5xdhC-4d63A:
undetectable		 5xdhA-4d63A:
22.39
5xdhC-4d63A:
22.39