SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4d6v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ9_A_CAMA503_0
(CYTOCHROME P450-CAM)		 4d6v G PROTEIN BETA
SUBUNIT GIB2
(Cryptococcus
neoformans) 		4 / 8 THR A 187
LEU A 184
VAL A 151
ASP A 171
 None
 1.05A 1dz9A-4d6vA:
undetectable		 1dz9A-4d6vA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GEB_A_CAMA418_0
(CYTOCHROME P450-CAM)		 4d6v G PROTEIN BETA
SUBUNIT GIB2
(Cryptococcus
neoformans) 		5 / 9 THR A 187
LEU A 184
ILE A 129
VAL A 151
ASP A 171
 None
 0.92A 1gebA-4d6vA:
undetectable		 1gebA-4d6vA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T85_A_CAMA422_0
(CYTOCHROME P450-CAM)		 4d6v G PROTEIN BETA
SUBUNIT GIB2
(Cryptococcus
neoformans) 		4 / 7 THR A 187
LEU A 184
VAL A 151
ASP A 171
 None
 1.03A 1t85A-4d6vA:
undetectable		 1t85A-4d6vA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UOF_A_PNNA1312_0
(DEACETOXYCEPHALOSPOR
IN C SYNTHETASE)		 4d6v G PROTEIN BETA
SUBUNIT GIB2
(Cryptococcus
neoformans) 		5 / 11 ASP A 126
HIS A 104
VAL A 121
SER A 167
VAL A 151
 None
 1.45A 1uofA-4d6vA:
undetectable		 1uofA-4d6vA:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_B_CAMB1416_0
(CYTOCHROME P450-CAM)		 4d6v G PROTEIN BETA
SUBUNIT GIB2
(Cryptococcus
neoformans) 		4 / 8 THR A 187
LEU A 184
VAL A 151
ASP A 171
 None
 1.08A 1uyuB-4d6vA:
undetectable		 1uyuB-4d6vA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRC_A_CAMA420_0
(CYTOCHROME P450-CAM)		 4d6v G PROTEIN BETA
SUBUNIT GIB2
(Cryptococcus
neoformans) 		4 / 7 THR A 187
LEU A 184
VAL A 151
ASP A 171
 None
 1.03A 1yrcA-4d6vA:
undetectable		 1yrcA-4d6vA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRD_A_CAMA420_0
(CYTOCHROME P450-CAM)		 4d6v G PROTEIN BETA
SUBUNIT GIB2
(Cryptococcus
neoformans) 		4 / 7 THR A 187
LEU A 184
VAL A 151
ASP A 171
 None
 1.03A 1yrdA-4d6vA:
undetectable		 1yrdA-4d6vA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_C_SPMC1434_1
(NITROALKANE OXIDASE)		 4d6v G PROTEIN BETA
SUBUNIT GIB2
(Cryptococcus
neoformans) 		5 / 12 VAL A 200
ALA A 207
LEU A 206
SER A 205
ASP A 203
 None
 0.95A 2c12C-4d6vA:
undetectable		 2c12C-4d6vA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_F_SPMF1433_1
(NITROALKANE OXIDASE)		 4d6v G PROTEIN BETA
SUBUNIT GIB2
(Cryptococcus
neoformans) 		5 / 11 VAL A 200
ALA A 207
LEU A 206
SER A 205
ASP A 203
 None
 0.94A 2c12F-4d6vA:
undetectable		 2c12F-4d6vA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_B_CAMB1421_0
(CYTOCHROME P450-CAM)		 4d6v G PROTEIN BETA
SUBUNIT GIB2
(Cryptococcus
neoformans) 		4 / 7 THR A 187
LEU A 184
VAL A 151
ASP A 171
 None
 1.01A 2feuB-4d6vA:
undetectable		 2feuB-4d6vA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWT_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 4d6v G PROTEIN BETA
SUBUNIT GIB2
(Cryptococcus
neoformans) 		4 / 7 THR A 187
LEU A 184
VAL A 151
ASP A 171
 None
 1.02A 2zwtA-4d6vA:
undetectable		 2zwtA-4d6vA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWU_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 4d6v G PROTEIN BETA
SUBUNIT GIB2
(Cryptococcus
neoformans) 		4 / 7 THR A 187
LEU A 184
VAL A 151
ASP A 171
 None
 1.03A 2zwuA-4d6vA:
undetectable		 2zwuA-4d6vA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 4d6v G PROTEIN BETA
SUBUNIT GIB2
(Cryptococcus
neoformans) 		4 / 7 THR A 187
LEU A 184
VAL A 151
ASP A 171
 None
 1.00A 3fwfA-4d6vA:
undetectable		 3fwfA-4d6vA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 4d6v G PROTEIN BETA
SUBUNIT GIB2
(Cryptococcus
neoformans) 		4 / 7 THR A 187
LEU A 184
VAL A 151
ASP A 171
 None
 1.00A 3fwfB-4d6vA:
undetectable		 3fwfB-4d6vA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWJ_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 4d6v G PROTEIN BETA
SUBUNIT GIB2
(Cryptococcus
neoformans) 		4 / 7 THR A 187
LEU A 184
VAL A 151
ASP A 171
 None
 1.05A 3fwjA-4d6vA:
undetectable		 3fwjA-4d6vA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_A_PNTA901_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 4d6v G PROTEIN BETA
SUBUNIT GIB2
(Cryptococcus
neoformans) 		5 / 12 ASP A 304
GLY A  16
SER A  35
VAL A  18
ASN A  10
 None
 1.21A 3hiiA-4d6vA:
2.2		 3hiiA-4d6vA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_B_PNTB901_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 4d6v G PROTEIN BETA
SUBUNIT GIB2
(Cryptococcus
neoformans) 		5 / 12 ASP A 304
GLY A  16
SER A  35
VAL A  18
ASN A  10
 None
 1.23A 3hiiB-4d6vA:
undetectable		 3hiiB-4d6vA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L63_A_CAMA440_0
(CAMPHOR
5-MONOOXYGENASE)		 4d6v G PROTEIN BETA
SUBUNIT GIB2
(Cryptococcus
neoformans) 		4 / 7 THR A 187
LEU A 184
VAL A 151
ASP A 171
 None
 0.98A 3l63A-4d6vA:
undetectable		 3l63A-4d6vA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_C_CELC682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4d6v G PROTEIN BETA
SUBUNIT GIB2
(Cryptococcus
neoformans) 		4 / 7 SER A 122
ARG A 155
ILE A 165
PHE A 156
 None
 0.87A 3ln1C-4d6vA:
undetectable		 3ln1C-4d6vA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4d6v G PROTEIN BETA
SUBUNIT GIB2
(Cryptococcus
neoformans) 		3 / 3 VAL A 164
SER A 157
LEU A 162
 None
 0.76A 3n8xA-4d6vA:
undetectable		 3n8xA-4d6vA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4d6v G PROTEIN BETA
SUBUNIT GIB2
(Cryptococcus
neoformans) 		4 / 7 THR A 187
LEU A 184
VAL A 151
ASP A 171
 None
 1.03A 3wrhA-4d6vA:
undetectable		 3wrhA-4d6vA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4d6v G PROTEIN BETA
SUBUNIT GIB2
(Cryptococcus
neoformans) 		4 / 7 THR A 187
LEU A 184
VAL A 151
ASP A 171
 None
 1.02A 3wrjA-4d6vA:
undetectable		 3wrjA-4d6vA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4d6v G PROTEIN BETA
SUBUNIT GIB2
(Cryptococcus
neoformans) 		4 / 7 THR A 187
LEU A 184
VAL A 151
ASP A 171
 None
 1.00A 3wrlA-4d6vA:
undetectable		 3wrlA-4d6vA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 4d6v G PROTEIN BETA
SUBUNIT GIB2
(Cryptococcus
neoformans) 		4 / 7 THR A 187
LEU A 184
VAL A 151
ASP A 171
 None
 1.01A 3wrlE-4d6vA:
undetectable		 3wrlE-4d6vA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4d6v G PROTEIN BETA
SUBUNIT GIB2
(Cryptococcus
neoformans) 		4 / 7 THR A 187
LEU A 184
VAL A 151
ASP A 171
 None
 1.02A 3wrmA-4d6vA:
undetectable		 3wrmA-4d6vA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_F_CAMF503_0
(CAMPHOR
5-MONOOXYGENASE)		 4d6v G PROTEIN BETA
SUBUNIT GIB2
(Cryptococcus
neoformans) 		4 / 7 THR A 187
LEU A 184
VAL A 151
ASP A 171
 None
 0.99A 3wrmF-4d6vA:
undetectable		 3wrmF-4d6vA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4A_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4d6v G PROTEIN BETA
SUBUNIT GIB2
(Cryptococcus
neoformans) 		4 / 8 THR A 187
LEU A 184
VAL A 151
ASP A 171
 None
 1.01A 4l4aA-4d6vA:
undetectable		 4l4aA-4d6vA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4B_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4d6v G PROTEIN BETA
SUBUNIT GIB2
(Cryptococcus
neoformans) 		4 / 8 THR A 187
LEU A 184
VAL A 151
ASP A 171
 None
 1.04A 4l4bA-4d6vA:
undetectable		 4l4bA-4d6vA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 4d6v G PROTEIN BETA
SUBUNIT GIB2
(Cryptococcus
neoformans) 		4 / 8 THR A 187
LEU A 184
VAL A 151
ASP A 171
 None
 0.95A 4l4cB-4d6vA:
undetectable		 4l4cB-4d6vA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4D_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4d6v G PROTEIN BETA
SUBUNIT GIB2
(Cryptococcus
neoformans) 		4 / 8 THR A 187
LEU A 184
VAL A 151
ASP A 171
 None
 1.06A 4l4dA-4d6vA:
undetectable		 4l4dA-4d6vA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4G_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4d6v G PROTEIN BETA
SUBUNIT GIB2
(Cryptococcus
neoformans) 		4 / 7 THR A 187
LEU A 184
VAL A 151
ASP A 171
 None
 1.06A 4l4gA-4d6vA:
undetectable		 4l4gA-4d6vA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPU_A_IPHA101_0
(INSULIN, CHAIN A
INSULIN, CHAIN B)		 4d6v G PROTEIN BETA
SUBUNIT GIB2
(Cryptococcus
neoformans) 		4 / 4 CYH A 249
LEU A 298
LEU A 289
ALA A 300
 None
 0.88A 5hpuA-4d6vA:
undetectable
5hpuB-4d6vA:
undetectable		 5hpuA-4d6vA:
6.08
5hpuB-4d6vA:
8.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4d6v G PROTEIN BETA
SUBUNIT GIB2
(Cryptococcus
neoformans) 		4 / 6 SER A 122
ARG A 155
ILE A 165
PHE A 156
 None
 1.00A 5jw1A-4d6vA:
undetectable		 5jw1A-4d6vA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_B_CELB602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4d6v G PROTEIN BETA
SUBUNIT GIB2
(Cryptococcus
neoformans) 		4 / 6 SER A 122
ARG A 155
ILE A 165
PHE A 156
 None
 0.90A 5jw1B-4d6vA:
undetectable		 5jw1B-4d6vA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4E_D_EDPD402_1
(PROTON-GATED ION
CHANNEL)		 4d6v G PROTEIN BETA
SUBUNIT GIB2
(Cryptococcus
neoformans) 		4 / 8 SER A  80
THR A  86
SER A  82
THR A  97
 None
 0.92A 5l4eA-4d6vA:
undetectable
5l4eB-4d6vA:
undetectable
5l4eC-4d6vA:
undetectable
5l4eD-4d6vA:
undetectable
5l4eE-4d6vA:
undetectable		 5l4eA-4d6vA:
21.89
5l4eB-4d6vA:
21.89
5l4eC-4d6vA:
21.89
5l4eD-4d6vA:
21.89
5l4eE-4d6vA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4E_D_EDPD402_1
(PROTON-GATED ION
CHANNEL)		 4d6v G PROTEIN BETA
SUBUNIT GIB2
(Cryptococcus
neoformans) 		4 / 8 THR A  97
SER A  80
THR A  86
SER A  82
 None
 0.89A 5l4eA-4d6vA:
undetectable
5l4eB-4d6vA:
undetectable
5l4eC-4d6vA:
undetectable
5l4eD-4d6vA:
undetectable
5l4eE-4d6vA:
undetectable		 5l4eA-4d6vA:
21.89
5l4eB-4d6vA:
21.89
5l4eC-4d6vA:
21.89
5l4eD-4d6vA:
21.89
5l4eE-4d6vA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VYH_A_FOLA409_0
(S PROTEIN)		 4d6v G PROTEIN BETA
SUBUNIT GIB2
(Cryptococcus
neoformans) 		5 / 10 HIS A  60
GLY A 301
THR A 287
ILE A  21
ALA A  34
 None
 1.30A 5vyhA-4d6vA:
undetectable		 5vyhA-4d6vA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WK9_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4d6v G PROTEIN BETA
SUBUNIT GIB2
(Cryptococcus
neoformans) 		4 / 7 THR A 187
LEU A 184
VAL A 151
ASP A 171
 None
 1.01A 5wk9A-4d6vA:
undetectable		 5wk9A-4d6vA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YSI_A_NCAA1001_0
(UBIQUITINATING/DEUBI
QUITINATING ENZYME
SDEA)		 4d6v G PROTEIN BETA
SUBUNIT GIB2
(Cryptococcus
neoformans) 		4 / 6 GLY A 301
SER A  35
THR A  33
VAL A 307
 None
 1.13A 5ysiA-4d6vA:
undetectable		 5ysiA-4d6vA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BZO_C_FI8C1201_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 4d6v G PROTEIN BETA
SUBUNIT GIB2
(Cryptococcus
neoformans) 		5 / 12 ILE A 236
THR A 252
VAL A 307
VAL A 309
SER A 303
 None
 1.14A 6bzoC-4d6vA:
undetectable		 6bzoC-4d6vA:
14.03