SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4d70'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1003_0
(ALDEHYDE
DEHYDROGENASE A)		 4d70 SORTASE FAMILY
PROTEIN
(Clostridium
perfringens) 		4 / 5 ILE A 143
LEU A 124
ALA A 183
PHE A 118
 None
 1.04A 2opxA-4d70A:
undetectable		 2opxA-4d70A:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_A_ADNA353_1
(ADENOSINE KINASE)		 4d70 SORTASE FAMILY
PROTEIN
(Clostridium
perfringens) 		5 / 12 ASN A 115
ILE A  89
GLY A  90
THR A  74
GLY A  59
 None
 0.96A 3uboA-4d70A:
undetectable		 3uboA-4d70A:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_A_T1CA404_1
(TETX2 PROTEIN)		 4d70 SORTASE FAMILY
PROTEIN
(Clostridium
perfringens) 		5 / 12 THR A 167
ASN A 103
GLY A  99
ALA A  77
GLY A  90
 None
 0.95A 3v3oA-4d70A:
undetectable		 3v3oA-4d70A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_D_ACTD502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4d70 SORTASE FAMILY
PROTEIN
(Clostridium
perfringens) 		3 / 3 GLY A 102
THR A 165
ASN A 160
 None
 0.70A 3v4tD-4d70A:
undetectable		 3v4tD-4d70A:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRI_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4d70 SORTASE FAMILY
PROTEIN
(Clostridium
perfringens) 		4 / 5 GLY A  59
THR A  34
ILE A  76
VAL A  75
 None
 0.86A 3wriA-4d70A:
undetectable		 3wriA-4d70A:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRI_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 4d70 SORTASE FAMILY
PROTEIN
(Clostridium
perfringens) 		4 / 5 GLY A  59
THR A  34
ILE A  76
VAL A  75
 None
 0.86A 3wriB-4d70A:
undetectable		 3wriB-4d70A:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_J_Z80J401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4d70 SORTASE FAMILY
PROTEIN
(Clostridium
perfringens) 		5 / 12 ILE A 121
ILE A 168
GLU A  31
ASN A  88
ILE A  65
 None
 1.19A 5lg3J-4d70A:
undetectable		 5lg3J-4d70A:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_B_PFLB407_1
(PROTON-GATED ION
CHANNEL)		 4d70 SORTASE FAMILY
PROTEIN
(Clostridium
perfringens) 		4 / 7 ILE A 168
ILE A 106
MET A 166
ILE A 132
 None
 0.88A 5murB-4d70A:
undetectable		 5murB-4d70A:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_C_CHDC401_0
(BILE SALT HYDROLASE)		 4d70 SORTASE FAMILY
PROTEIN
(Clostridium
perfringens) 		4 / 8 LEU A 124
ILE A  65
PHE A 139
LEU A 185
 None
 0.86A 5y7pC-4d70A:
undetectable		 5y7pC-4d70A:
22.94