SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4d73'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA131_0
(FATTY ACID-BINDING
PROTEIN)		 4d73 1-CYS PEROXIREDOXIN
(Plasmodium
falciparum) 		5 / 11 LEU B 106
VAL B  68
THR B  95
PHE B  99
HIS B  96
 None
 1.41A 1tw4A-4d73B:
undetectable		 1tw4A-4d73B:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_2
(TUBULIN ALPHA CHAIN)		 4d73 1-CYS PEROXIREDOXIN
(Plasmodium
falciparum) 		4 / 5 VAL B 231
ASN B 230
VAL B 197
ILE B 199
 None
 0.99A 1z2bC-4d73B:
undetectable		 1z2bC-4d73B:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IE8_A_CHDA201_0
(REGULATORY PROTEIN)		 4d73 1-CYS PEROXIREDOXIN
(Plasmodium
falciparum) 		5 / 12 LEU B  98
THR B 145
ILE B 144
TYR B 142
LEU B 152
 None
 1.16A 6ie8A-4d73B:
undetectable		 6ie8A-4d73B:
16.02