SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4d7p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 4d7p SUPEROXIDE REDUCTASE
(Giardia
intestinalis) 		3 / 3 GLU A  17
HIS A  40
HIS A  19
 FE  A 201 (-3.7A)
FE  A 201 (-3.4A)
FE  A 201 (-3.2A)
 0.66A 1oe2A-4d7pA:
undetectable		 1oe2A-4d7pA:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQE_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 4d7p SUPEROXIDE REDUCTASE
(Giardia
intestinalis) 		4 / 4 HIS A  19
HIS A 102
HIS A  46
HIS A  40
 FE  A 201 (-3.2A)
FE  A 201 (-3.4A)
FE  A 201 (-3.3A)
FE  A 201 (-3.4A)
 1.37A 2fqeA-4d7pA:
undetectable		 2fqeA-4d7pA:
11.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQE_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 4d7p SUPEROXIDE REDUCTASE
(Giardia
intestinalis) 		4 / 4 HIS A  46
HIS A 102
HIS A  19
HIS A  40
 FE  A 201 (-3.3A)
FE  A 201 (-3.4A)
FE  A 201 (-3.2A)
FE  A 201 (-3.4A)
 1.30A 2fqeA-4d7pA:
undetectable		 2fqeA-4d7pA:
11.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQF_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 4d7p SUPEROXIDE REDUCTASE
(Giardia
intestinalis) 		4 / 4 HIS A  19
HIS A 102
HIS A  46
HIS A  40
 FE  A 201 (-3.2A)
FE  A 201 (-3.4A)
FE  A 201 (-3.3A)
FE  A 201 (-3.4A)
 1.38A 2fqfA-4d7pA:
undetectable		 2fqfA-4d7pA:
11.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQG_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 4d7p SUPEROXIDE REDUCTASE
(Giardia
intestinalis) 		4 / 4 HIS A  19
HIS A 102
HIS A  46
HIS A  40
 FE  A 201 (-3.2A)
FE  A 201 (-3.4A)
FE  A 201 (-3.3A)
FE  A 201 (-3.4A)
 1.35A 2fqgA-4d7pA:
undetectable		 2fqgA-4d7pA:
11.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_A_DVAA8_0
(GRAMICIDIN D)		 4d7p SUPEROXIDE REDUCTASE
(Giardia
intestinalis) 		3 / 3 VAL A  96
TRP A 105
VAL A  20
 None
 0.92A 2izqA-4d7pA:
undetectable
2izqB-4d7pA:
undetectable		 2izqA-4d7pA:
8.05
2izqB-4d7pA:
8.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB8_0
(GRAMICIDIN D)		 4d7p SUPEROXIDE REDUCTASE
(Giardia
intestinalis) 		3 / 3 VAL A  20
VAL A  96
TRP A 105
 None
 0.81A 3l8lA-4d7pA:
undetectable
3l8lB-4d7pA:
undetectable		 3l8lA-4d7pA:
8.05
3l8lB-4d7pA:
8.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1004_0
(BLUE COPPER OXIDASE
CUEO)		 4d7p SUPEROXIDE REDUCTASE
(Giardia
intestinalis) 		4 / 4 HIS A  19
HIS A 102
HIS A  46
HIS A  40
 FE  A 201 (-3.2A)
FE  A 201 (-3.4A)
FE  A 201 (-3.3A)
FE  A 201 (-3.4A)
 1.38A 4ef3A-4d7pA:
undetectable		 4ef3A-4d7pA:
11.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_2
(TUBULIN BETA CHAIN)		 4d7p SUPEROXIDE REDUCTASE
(Giardia
intestinalis) 		5 / 12 CYH A  34
ASN A 100
ILE A  51
ALA A  97
ILE A  71
 None
 1.00A 5eypB-4d7pA:
undetectable		 5eypB-4d7pA:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA503_0
(LACCASE 2)		 4d7p SUPEROXIDE REDUCTASE
(Giardia
intestinalis) 		4 / 4 HIS A  46
HIS A 102
HIS A  19
HIS A  40
 FE  A 201 (-3.3A)
FE  A 201 (-3.4A)
FE  A 201 (-3.2A)
FE  A 201 (-3.4A)
 1.25A 5mejA-4d7pA:
undetectable		 5mejA-4d7pA:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA503_0
(LACCASE 2)		 4d7p SUPEROXIDE REDUCTASE
(Giardia
intestinalis) 		4 / 4 HIS A  46
HIS A 102
HIS A  19
HIS A  40
 FE  A 201 (-3.3A)
FE  A 201 (-3.4A)
FE  A 201 (-3.2A)
FE  A 201 (-3.4A)
 1.25A 5mewA-4d7pA:
undetectable		 5mewA-4d7pA:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA503_0
(LACCASE 2)		 4d7p SUPEROXIDE REDUCTASE
(Giardia
intestinalis) 		4 / 4 HIS A  46
HIS A 102
HIS A  19
HIS A  40
 FE  A 201 (-3.3A)
FE  A 201 (-3.4A)
FE  A 201 (-3.2A)
FE  A 201 (-3.4A)
 1.25A 5mhuA-4d7pA:
undetectable		 5mhuA-4d7pA:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA503_0
(LACCASE 2)		 4d7p SUPEROXIDE REDUCTASE
(Giardia
intestinalis) 		4 / 4 HIS A  46
HIS A 102
HIS A  19
HIS A  40
 FE  A 201 (-3.3A)
FE  A 201 (-3.4A)
FE  A 201 (-3.2A)
FE  A 201 (-3.4A)
 1.25A 5mhvA-4d7pA:
undetectable		 5mhvA-4d7pA:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA603_0
(LACCASE 2)		 4d7p SUPEROXIDE REDUCTASE
(Giardia
intestinalis) 		4 / 4 HIS A  46
HIS A 102
HIS A  19
HIS A  40
 FE  A 201 (-3.3A)
FE  A 201 (-3.4A)
FE  A 201 (-3.2A)
FE  A 201 (-3.4A)
 1.25A 5mhwA-4d7pA:
undetectable		 5mhwA-4d7pA:
10.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA603_0
(LACCASE 2)		 4d7p SUPEROXIDE REDUCTASE
(Giardia
intestinalis) 		4 / 4 HIS A  46
HIS A 102
HIS A  19
HIS A  40
 FE  A 201 (-3.3A)
FE  A 201 (-3.4A)
FE  A 201 (-3.2A)
FE  A 201 (-3.4A)
 1.24A 5mhxA-4d7pA:
undetectable		 5mhxA-4d7pA:
10.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA603_0
(LACCASE 2)		 4d7p SUPEROXIDE REDUCTASE
(Giardia
intestinalis) 		4 / 4 HIS A  46
HIS A 102
HIS A  19
HIS A  40
 FE  A 201 (-3.3A)
FE  A 201 (-3.4A)
FE  A 201 (-3.2A)
FE  A 201 (-3.4A)
 1.24A 5mhyA-4d7pA:
undetectable		 5mhyA-4d7pA:
10.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA603_0
(LACCASE 2)		 4d7p SUPEROXIDE REDUCTASE
(Giardia
intestinalis) 		4 / 4 HIS A  46
HIS A 102
HIS A  19
HIS A  40
 FE  A 201 (-3.3A)
FE  A 201 (-3.4A)
FE  A 201 (-3.2A)
FE  A 201 (-3.4A)
 1.24A 5mhzA-4d7pA:
undetectable		 5mhzA-4d7pA:
10.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA603_0
(LACCASE 2)		 4d7p SUPEROXIDE REDUCTASE
(Giardia
intestinalis) 		4 / 4 HIS A  46
HIS A 102
HIS A  19
HIS A  40
 FE  A 201 (-3.3A)
FE  A 201 (-3.4A)
FE  A 201 (-3.2A)
FE  A 201 (-3.4A)
 1.24A 5mi1A-4d7pA:
undetectable		 5mi1A-4d7pA:
10.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA603_0
(LACCASE 2)		 4d7p SUPEROXIDE REDUCTASE
(Giardia
intestinalis) 		4 / 4 HIS A  46
HIS A 102
HIS A  19
HIS A  40
 FE  A 201 (-3.3A)
FE  A 201 (-3.4A)
FE  A 201 (-3.2A)
FE  A 201 (-3.4A)
 1.24A 5mi2A-4d7pA:
undetectable		 5mi2A-4d7pA:
10.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA603_0
(LACCASE 2)		 4d7p SUPEROXIDE REDUCTASE
(Giardia
intestinalis) 		4 / 4 HIS A  46
HIS A 102
HIS A  19
HIS A  40
 FE  A 201 (-3.3A)
FE  A 201 (-3.4A)
FE  A 201 (-3.2A)
FE  A 201 (-3.4A)
 1.24A 5miaA-4d7pA:
undetectable		 5miaA-4d7pA:
10.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA603_0
(LACCASE 2)		 4d7p SUPEROXIDE REDUCTASE
(Giardia
intestinalis) 		4 / 4 HIS A  46
HIS A 102
HIS A  19
HIS A  40
 FE  A 201 (-3.3A)
FE  A 201 (-3.4A)
FE  A 201 (-3.2A)
FE  A 201 (-3.4A)
 1.25A 5mibA-4d7pA:
undetectable		 5mibA-4d7pA:
10.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA603_0
(LACCASE 2)		 4d7p SUPEROXIDE REDUCTASE
(Giardia
intestinalis) 		4 / 4 HIS A  46
HIS A 102
HIS A  19
HIS A  40
 FE  A 201 (-3.3A)
FE  A 201 (-3.4A)
FE  A 201 (-3.2A)
FE  A 201 (-3.4A)
 1.24A 5micA-4d7pA:
undetectable		 5micA-4d7pA:
10.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA603_0
(LACCASE 2)		 4d7p SUPEROXIDE REDUCTASE
(Giardia
intestinalis) 		4 / 4 HIS A  46
HIS A 102
HIS A  19
HIS A  40
 FE  A 201 (-3.3A)
FE  A 201 (-3.4A)
FE  A 201 (-3.2A)
FE  A 201 (-3.4A)
 1.24A 5midA-4d7pA:
undetectable		 5midA-4d7pA:
10.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA603_0
(LACCASE 2)		 4d7p SUPEROXIDE REDUCTASE
(Giardia
intestinalis) 		4 / 4 HIS A  46
HIS A 102
HIS A  19
HIS A  40
 FE  A 201 (-3.3A)
FE  A 201 (-3.4A)
FE  A 201 (-3.2A)
FE  A 201 (-3.4A)
 1.24A 5mieA-4d7pA:
undetectable		 5mieA-4d7pA:
10.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA603_0
(LACCASE 2)		 4d7p SUPEROXIDE REDUCTASE
(Giardia
intestinalis) 		4 / 4 HIS A  46
HIS A 102
HIS A  19
HIS A  40
 FE  A 201 (-3.3A)
FE  A 201 (-3.4A)
FE  A 201 (-3.2A)
FE  A 201 (-3.4A)
 1.23A 5migA-4d7pA:
undetectable		 5migA-4d7pA:
10.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NM5_B_LOCB502_2
(TUBULIN BETA-2B
CHAIN)		 4d7p SUPEROXIDE REDUCTASE
(Giardia
intestinalis) 		5 / 12 CYH A  34
ASN A 100
ILE A  51
ALA A  97
ILE A  71
 None
 1.10A 5nm5B-4d7pA:
undetectable		 5nm5B-4d7pA:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_2
(TUBULIN BETA CHAIN)		 4d7p SUPEROXIDE REDUCTASE
(Giardia
intestinalis) 		5 / 12 CYH A  34
ASN A 100
ILE A  51
ALA A  97
ILE A  71
 None
 1.05A 5xiwD-4d7pA:
undetectable		 5xiwD-4d7pA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA606_0
(TYROSINASE)		 4d7p SUPEROXIDE REDUCTASE
(Giardia
intestinalis) 		4 / 4 HIS A  46
CYH A  99
HIS A  19
HIS A 102
 FE  A 201 (-3.3A)
FE  A 201 (-2.3A)
FE  A 201 (-3.2A)
FE  A 201 (-3.4A)
 1.42A 5zrdA-4d7pA:
2.3		 5zrdA-4d7pA:
10.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA606_0
(TYROSINASE)		 4d7p SUPEROXIDE REDUCTASE
(Giardia
intestinalis) 		4 / 4 HIS A 102
CYH A  99
HIS A  46
HIS A  19
 FE  A 201 (-3.4A)
FE  A 201 (-2.3A)
FE  A 201 (-3.3A)
FE  A 201 (-3.2A)
 1.42A 5zrdA-4d7pA:
2.3		 5zrdA-4d7pA:
10.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA606_0
(TYROSINASE)		 4d7p SUPEROXIDE REDUCTASE
(Giardia
intestinalis) 		4 / 4 HIS A 102
CYH A  99
HIS A  46
HIS A  40
 FE  A 201 (-3.4A)
FE  A 201 (-2.3A)
FE  A 201 (-3.3A)
FE  A 201 (-3.4A)
 1.27A 5zrdA-4d7pA:
2.3		 5zrdA-4d7pA:
10.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB607_0
(TYROSINASE)		 4d7p SUPEROXIDE REDUCTASE
(Giardia
intestinalis) 		4 / 5 HIS A 102
CYH A  99
HIS A  46
HIS A  40
 FE  A 201 (-3.4A)
FE  A 201 (-2.3A)
FE  A 201 (-3.3A)
FE  A 201 (-3.4A)
 1.20A 5zrdB-4d7pA:
3.4		 5zrdB-4d7pA:
10.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD606_0
(TYROSINASE)		 4d7p SUPEROXIDE REDUCTASE
(Giardia
intestinalis) 		4 / 5 HIS A 102
CYH A  99
HIS A  46
HIS A  40
 FE  A 201 (-3.4A)
FE  A 201 (-2.3A)
FE  A 201 (-3.3A)
FE  A 201 (-3.4A)
 1.20A 5zrdD-4d7pA:
3.6		 5zrdD-4d7pA:
10.93