SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4d7w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_A_TESA325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 4d7w SORTASE FAMILY
PROTEIN
(Streptococcus
agalactiae) 		4 / 7 LEU A  92
HIS A 116
THR A 142
TYR A  67
 None
 1.27A 1afsA-4d7wA:
undetectable		 1afsA-4d7wA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_B_TESB325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 4d7w SORTASE FAMILY
PROTEIN
(Streptococcus
agalactiae) 		4 / 7 LEU A  92
HIS A 116
THR A 142
TYR A  67
 None
 1.27A 1afsB-4d7wA:
undetectable		 1afsB-4d7wA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AQ7_B_AG2B4_1
(TRYPSIN
AERUGINOSIN 98-B)		 4d7w SORTASE FAMILY
PROTEIN
(Streptococcus
agalactiae) 		5 / 8 HIS A 129
ASP A 204
GLN A 206
SER A 133
GLY A 139
 None
 1.37A 1aq7A-4d7wA:
undetectable		 1aq7A-4d7wA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYO_A_LNLA1216_1
(LIPOPROTEIN LPPX)		 4d7w SORTASE FAMILY
PROTEIN
(Streptococcus
agalactiae) 		4 / 5 LEU A 197
ILE A 145
LEU A 146
SER A 147
 None
 0.94A 2byoA-4d7wA:
undetectable		 2byoA-4d7wA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_D_SNLD4001_2
(MINERALOCORTICOID
RECEPTOR)		 4d7w SORTASE FAMILY
PROTEIN
(Streptococcus
agalactiae) 		4 / 5 LEU A 222
LEU A 130
CYH A 211
THR A 212
 None
 1.42A 2oaxD-4d7wA:
undetectable		 2oaxD-4d7wA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0A_C_GLYC73_0
(NONSTRUCTURAL
PROTEIN 1)		 4d7w SORTASE FAMILY
PROTEIN
(Streptococcus
agalactiae) 		4 / 4 ASP A 162
ASP A 160
SER A 159
ARG A 150
 None
 1.26A 2z0aC-4d7wA:
undetectable		 2z0aC-4d7wA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_A_BRLA501_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4d7w SORTASE FAMILY
PROTEIN
(Streptococcus
agalactiae) 		4 / 5 GLY A 148
LEU A 164
ILE A 110
LEU A 197
 None
 0.83A 4o8fA-4d7wA:
undetectable		 4o8fA-4d7wA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZXI_A_GLYA1402_0
(TYROCIDINE
SYNTHETASE 3)		 4d7w SORTASE FAMILY
PROTEIN
(Streptococcus
agalactiae) 		4 / 7 ASP A  95
ILE A  94
GLY A 101
THR A  97
 None
 0.92A 4zxiA-4d7wA:
undetectable		 4zxiA-4d7wA:
10.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_B_TLFB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4d7w SORTASE FAMILY
PROTEIN
(Streptococcus
agalactiae) 		3 / 3 TYR A 181
TYR A  88
SER A 133
 None
 0.80A 5iktB-4d7wA:
undetectable		 5iktB-4d7wA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U4S_A_BEZA301_0
(PUTATIVE SHORT CHAIN
DEHYDROGENASE)		 4d7w SORTASE FAMILY
PROTEIN
(Streptococcus
agalactiae) 		4 / 7 ASN A  68
ILE A  60
LEU A  92
LEU A 135
 None
 1.03A 5u4sA-4d7wA:
undetectable		 5u4sA-4d7wA:
18.30