SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4d7x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4001_1
(SERUM ALBUMIN)		 4d7x MEDIATOR OF RNA
POLYMERASE II
TRANSCRIPTION
SUBUNIT 15
([Candida]
glabrata) 		4 / 5 LYS A  39
ALA A  37
ASP A  33
GLY A  32
 None
 1.10A 1e7cA-4d7xA:
3.1		 1e7cA-4d7xA:
9.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4d7x MEDIATOR OF RNA
POLYMERASE II
TRANSCRIPTION
SUBUNIT 15
([Candida]
glabrata) 		4 / 5 ARG A  76
MET A  24
THR A  21
LEU A  20
 None
 1.42A 2eimJ-4d7xA:
undetectable		 2eimJ-4d7xA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4d7x MEDIATOR OF RNA
POLYMERASE II
TRANSCRIPTION
SUBUNIT 15
([Candida]
glabrata) 		4 / 5 ARG A  76
MET A  24
THR A  21
LEU A  20
 None
 1.38A 2eimW-4d7xA:
undetectable		 2eimW-4d7xA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 4d7x MEDIATOR OF RNA
POLYMERASE II
TRANSCRIPTION
SUBUNIT 15
([Candida]
glabrata) 		4 / 5 ARG A  76
MET A  24
THR A  21
LEU A  20
 None
 1.38A 3ag2J-4d7xA:
undetectable		 3ag2J-4d7xA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 4d7x MEDIATOR OF RNA
POLYMERASE II
TRANSCRIPTION
SUBUNIT 15
([Candida]
glabrata) 		4 / 5 ARG A  76
MET A  24
THR A  21
LEU A  20
 None
 1.40A 3ag4J-4d7xA:
undetectable		 3ag4J-4d7xA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYE_B_YTZB902_1
(DIHYDROPTEROATE
SYNTHASE)		 4d7x MEDIATOR OF RNA
POLYMERASE II
TRANSCRIPTION
SUBUNIT 15
([Candida]
glabrata) 		3 / 3 PHE A  47
LYS A  54
SER A  55
 None
 1.35A 3tyeB-4d7xA:
undetectable		 3tyeB-4d7xA:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4d7x MEDIATOR OF RNA
POLYMERASE II
TRANSCRIPTION
SUBUNIT 15
([Candida]
glabrata) 		4 / 5 ARG A  76
MET A  24
THR A  21
LEU A  20
 None
 1.36A 5x1bW-4d7xA:
undetectable		 5x1bW-4d7xA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4d7x MEDIATOR OF RNA
POLYMERASE II
TRANSCRIPTION
SUBUNIT 15
([Candida]
glabrata) 		4 / 5 ARG A  76
MET A  24
THR A  21
LEU A  20
 None
 1.35A 5x1fW-4d7xA:
undetectable		 5x1fW-4d7xA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4d7x MEDIATOR OF RNA
POLYMERASE II
TRANSCRIPTION
SUBUNIT 15
([Candida]
glabrata) 		4 / 5 ARG A  76
MET A  24
THR A  21
LEU A  20
 None
 1.44A 6nknJ-4d7xA:
undetectable		 6nknJ-4d7xA:
18.60