SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4d82'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_B_BEZB1162_0
(PEROXIREDOXIN 5)		 4d82 AAA ATPASE, CENTRAL
DOMAIN PROTEIN
(Metallosphaera
sedula) 		4 / 8 PRO A 270
PRO A 140
GLY A 141
CYH A 142
 None
None
ADP  A1367 (-3.2A)
None
 0.84A 1h4oB-4d82A:
undetectable		 1h4oB-4d82A:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_G_BEZG1162_0
(PEROXIREDOXIN 5)		 4d82 AAA ATPASE, CENTRAL
DOMAIN PROTEIN
(Metallosphaera
sedula) 		4 / 8 PRO A 270
PRO A 140
GLY A 141
CYH A 142
 None
None
ADP  A1367 (-3.2A)
None
 0.80A 1h4oG-4d82A:
undetectable		 1h4oG-4d82A:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OC3_A_BEZA201_0
(PEROXIREDOXIN 5)		 4d82 AAA ATPASE, CENTRAL
DOMAIN PROTEIN
(Metallosphaera
sedula) 		4 / 8 PRO A 270
PRO A 140
GLY A 141
CYH A 142
 None
None
ADP  A1367 (-3.2A)
None
 0.85A 1oc3A-4d82A:
undetectable		 1oc3A-4d82A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD507_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 4d82 AAA ATPASE, CENTRAL
DOMAIN PROTEIN
(Metallosphaera
sedula) 		4 / 7 PHE A 200
ALA A 246
ILE A 147
ILE A 265
 None
 0.66A 1oniD-4d82A:
undetectable
1oniF-4d82A:
undetectable		 1oniD-4d82A:
18.18
1oniF-4d82A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PLW_A_SAMA203_1
(RIBOSOMAL RNA
METHYLTRANSFERASE,
PUTATIVE)		 4d82 AAA ATPASE, CENTRAL
DOMAIN PROTEIN
(Metallosphaera
sedula) 		3 / 3 SER A 166
ASP A 205
ASP A 202
 None
 0.78A 2plwA-4d82A:
undetectable		 2plwA-4d82A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWW_A_SFXA801_1
(TRANSPORTER)		 4d82 AAA ATPASE, CENTRAL
DOMAIN PROTEIN
(Metallosphaera
sedula) 		5 / 12 GLY A 133
ILE A 199
PHE A 261
ALA A 148
ASP A 202
 None
 1.10A 3gwwA-4d82A:
undetectable		 3gwwA-4d82A:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUK_A_RBFA201_2
(BLUE-LIGHT
PHOTORECEPTOR)		 4d82 AAA ATPASE, CENTRAL
DOMAIN PROTEIN
(Metallosphaera
sedula) 		5 / 9 LEU A 278
VAL A 313
ILE A 312
LEU A 344
GLY A 303
 None
 1.09A 4kukA-4d82A:
undetectable		 4kukA-4d82A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_C_ACTC401_0
(PROTON-GATED ION
CHANNEL)		 4d82 AAA ATPASE, CENTRAL
DOMAIN PROTEIN
(Metallosphaera
sedula) 		4 / 7 ILE A 182
PHE A 183
VAL A 162
ILE A 201
 None
 0.96A 4zzbC-4d82A:
undetectable
4zzbD-4d82A:
undetectable		 4zzbC-4d82A:
21.80
4zzbD-4d82A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCN_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4d82 AAA ATPASE, CENTRAL
DOMAIN PROTEIN
(Metallosphaera
sedula) 		6 / 12 LEU A 112
ILE A 134
GLY A 245
ILE A 198
LEU A 226
LEU A 207
 None
 1.27A 5ycnA-4d82A:
undetectable		 5ycnA-4d82A:
25.15